Results 101 to 110 of about 5,243,950 (288)

Animal stroke models and outcome evaluation: A review

Animal Models and Experimental Medicine, EarlyView.
Rodents are the preeminent stroke model species. Large animal models exist too, but are poorly standardized. Ischemic and hemorrhagic experimental models are available, with the intraluminal filament model being predominant. Outcomes are evaluated via quantifying subjects' sensorimotor impairment, cognitive memory faculties, degree of cellular ...
Solsa Cariba, Helen M. Atkinson, Anthony K. C. Chan   +2 more
wiley   +1 more source

The influence of hyperthermia on intracranial pressure, cerebral oximetry and cerebral metabolism in traumatic brain injury

Upsala Journal of Medical Sciences, 2017
Background: Hyperthermia is a common secondary insult in traumatic brain injury (TBI). The aim was to evaluate the relationship between hyperthermia and intracranial pressure (ICP), and if intracranial compliance and cerebral blood flow (CBF) pressure ...
Lena Nyholm, Tim Howells, Anders Lewén, Lars Hillered, Per Enblad   +4 more
doaj   +1 more source

Intracranial pressure monitoring in traumatic brain injury: a scoping review

This preregistration describes a scoping review protocol to map invasive and non-invasive intracranial pressure (ICP) monitoring modalities in traumatic brain injury (TBI), their uptake, outcome measures, and ...
Mahdi Sharif-Alhoseini, Negin Safari Dehnavi   +1 more
core   +1 more source

Monitoring of autoregulation using intracerebral microdialysis in patients with severe head injury

, 2005
We evaluated the performance of continuous intracerebral microdialysis to indicate the autoregulatory reserve in 36 severely headinjured patients. All patients received standard treatment with intracranial pressure (ICP) monitoring. A microdialysis probe
Lam, J. M.K., Gin, T., Chan, M. T.V., Ng, S. C.P., Poon, W. S.   +4 more
core   +1 more source

Hippocampal Seizure‐Related Burden is Associated with Accelerated Long‐Term Forgetting in Focal Epilepsy

Annals of Neurology, EarlyView.
Objective Memory impairment is a frequent comorbidity of focal epilepsy, incompletely explained by seizure frequency or structural pathology. Ictal and postictal hippocampal dysfunction disrupt memory processes, but their cumulative impact remains poorly quantified.
Ionuț‐Flavius Bratu, Isabelle Lambert, Olivier Felician, Samuel Medina Villalon, Agnès Trébuchon, Fabrice Bartolomei   +5 more
wiley   +1 more source

Simultaneous Monitoring of Intracranial Pressure and Cerebral Blood Flow in Patients with Severe Brain Injury [PDF]

, 2018
37 patients with severe brain injury (admission Glasgow Coma Score 8 or below) were simultaneously monitored for intracranialand cerebral perfusion pressure and cerebral blood flow using transcranial Doppler ultrasonography.
Grishin, Vyacheslav, Romanukha, Dmytro, Skripnik, Alexander, Sirko, Andriy, Yovenko, Igor   +4 more
core   +1 more source

Centrum Semiovale Perivascular Spaces Predict First Hemorrhagic Lesion in Asymptomatic Amyloid‐Positive Individuals

Annals of Neurology, EarlyView.
Objective Identification of cerebral amyloid angiopathy (CAA) before its hemorrhagic manifestations remains limited. We aimed to determine whether severe enlarged perivascular spaces in the centrum semiovale (EPVS‐CSO) identify a prehemorrhagic stage of sporadic CAA by predicting the first appearance of CAA‐related hemorrhagic lesions or incident ...
Baris Alten, Elif Gokcal, Reisa A. Sperling, Zahra Shirzadi, Jasmeer P. Chhatwal, M. Edip Gurol, Scott E. Kasner, Steven M. Greenberg, Brett L. Cucchiara   +8 more
wiley   +1 more source

Brain Stethoscope: A Non-invasive Method for Monitoring Intracranial Pressure [PDF]

, 2018
Monitoring intracranial pressure (ICP) is important for patients with increased intracranial pressure. Invasive methods of ICP monitoring include lumbar puncture manometry, which requires high precision, is costly, and can lead to complications.
Azad, Md Khurshidul
core  

Tackling cancer stemness with nanotechnology in the era of precision medicine

BMEMat, EarlyView.
Precise customization of nanoparticles (NPs) enables active targeting of cancer stem cells (CSCs), thereby improving drug delivery and therapeutic efficacy. NP‐based probing enhances CSC detection through imaging and liquid biopsy, whereas diverse therapeutic payloads improve therapeutic outcomes.
Shaolei Guo, Shun Yao, Lihui Meng, Chunyuan Chen, Yuechu Lucinda Lu, Rong Lu, Kashif Rafiq Zahid, Umar Raza, Qingzhi Wu, Wenli Chen   +9 more
wiley   +1 more source

Chiari I Malformation: Review and Update of Current Treatment Options

Clinical Anatomy, EarlyView.
ABSTRACT The pathophysiology of Chiari malformation type I (CM‐I) is complex, involving structural abnormalities at the craniovertebral junction that result in herniation of the cerebellar tonsils through the foramen magnum. In this study, we aim to present and evaluate current treatment options for CM‐I, with a focus on evidence‐based clinical ...
Jordan J. Lo, Shuhei Shiino, Stephen Z. Shapiro, Brianna L. Hines, Noritaka Komune, Carmine Antonio Donofrio, Filippo Badaloni, Antonio Fioravanti, Joseph Lockwood, C. J. Bui, Aaron S. Dumont, R. Shane Tubbs   +11 more
wiley   +1 more source