Results 71 to 80 of about 5,243,950 (288)

Intracranial pressure monitoring in severe traumatic brain injury [PDF]

, 2014
Intracranial pressure monitoring seems to be an indispensable stage in management of severe traumatic brain injured patient. Since 2009, this technique completes our trauma protocol. The study has been carried out from 2011 to 2013 in Prof. Dr. N.
Iencean, A. Şt., Iordache, A, Apetrei, Al. Cosmin, Iliescu, B., Poeata, Ion   +4 more
core   +1 more source

Intracranial Pressure Monitoring in Head Injury

, 2020
Intracranial pressure (ICP) is well recognised as a critical parameter to both measure and influence in the management of the head injured patient. Since Lundberg’s seminal studies, ICP has arguably become the major focus of monitoring in head injury, as
Wells, A.J., Hutchinson, P.J.A., Smielewski, P., Trivedi, R.A.   +3 more
core   +1 more source

Targeting LDHA Palmitoylation Sensitizes GBM to Chemoradiotherapy via Suppressing Palmitic Acid Induced Glycolytic Reprogramming

Advanced Science, EarlyView.
Mesenchymal GSCs preferentially uptake palmitic acid, thereby promoting ZDHHC12‐mediated LDHA palmitoylation. This modification enhances LDHA enzymatic activity, drives glycolytic reprogramming, and facilitates exosomal LDHA‐mediated TAM regulation.
Zijie Gao, Rongrong Zhao, Zheyuan Chen, Qingtong Wang, Huanyu Yang, Boyan Li, Yanhua Qi, Shulin Zhao, Jixing Zhao, Jiawei Qiu, Ziwen Pan, Zhe Han, Ruochuan Li, Huize Xia, Weijie Tang, Xing Guo, Ping Zhang, Hongyu Zhao, Xu Qian, Gang Li, Hao Xue   +20 more
wiley   +1 more source

The Costs of a Quiet Disorder: Direct and Indirect Costs of Idiopathic Intracranial Hypertension [PDF]

Idiopathic Intracranial Hypertension (IIH; pseudotumor cerebri) is a disorder with a reported incidence rate of one to three per 100,000 people in the general population.
Brenna Lobb, Daniel Friesner, Robert Rosenman, Emanuel Tanne   +3 more
core  

Targeting the KAT7/H3K14ac/RAC2 Axis Mediates OXPHOS to Promote Stemness Maintenance and Malignancy in Glioblastoma

Advanced Science, EarlyView.
SOX2 upregulates KAT7 in glioma stem cells, where KAT7 deposits H3K14 acetylation at the RAC2 promoter to activate RAC2 transcription. RAC2‐GTP subsequently promotes PAK1/2/3 phosphorylation, increasing tricarboxylic acid cycle flux and mitochondrial respiration to support glioblastoma malignancy.
Jilong Liu, Yanfei Sun, Yuehua Zhu, Guangjing Mu, Jiazheng Wang, Liangliang Wang, Feihu Zhao, Zhimin Zhao, Jian Wang, Ying He, Zheng Jiang, Xingang Li, Mingzhi Han, Bin Huang   +13 more
wiley   +1 more source

Global traumatic brain injury intracranial pressure: from monitoring to surgical decision

Frontiers in Neurology
Traumatic brain injury (TBI) is a significant global public health issue, heavily impacting human health, especially in low-and middle-income areas. Despite numerous guidelines and consensus statements, TBI fatality rates remain high. The pathogenesis of
Dan Zhang, Yanzhi Sheng, Chengbin Wang, Wei Chen, Xiaofeng Shi   +4 more
doaj   +1 more source

Ocular Ultrasonography: A Useful Instrument in Patients with Trauma Brain Injury in Emergency Service

Emergency Medicine International, 2019
The measurement of the optic nerve sheath by ocular ultrasonography might be an indirect method to assess the quickly increase of the intracranial pressure in patients with moderate trauma brain injury, taking into account that an important proportion of
Julie Natalie Jimenez Restrepo, Oscar Javier León, Leonardo Alexander Quevedo Florez   +2 more
doaj   +1 more source

Remote Ischemic Post‐Conditioning Preserves the Neurovascular Unit by Brain‐Derived Gas6 That Drives Monocyte‐Derived Macrophage Reprogramming via Axl and Vimentin after SAH

Advanced Science, EarlyView.
Subarachnoid hemorrhage (SAH) triggers monocyte‐derived macrophage (MDM) infiltration and M1‐like polarization via Vimentin upregulation, leading to neurovascular unit disruption and cognitive dysfunction. Remote ischemic postconditioning (RIPostC) upregulates neuronal Gas6, which activates Axl on MDMs to downregulate Vimentin and drive reparative M2 ...
Yajun Zhu, Zichao Huang, Xi Rong, Xingwei Lei, Fuming Liang, Xiaoguo Li, Jiru Zhou, Yu Wang, Yifan Huang, Shuang Tang, Jianjun Zhong, Jin Yan, Hongji Deng, Chun Zeng, Zongduo Guo   +14 more
wiley   +1 more source

Severe head injuries and intracranial pressure monitoring outcome in Southern Iran

Journal of Research in Medical Sciences, 2006
BACKGROUND: Head injury is still a major cause of death and disability. Despite advances in intensive monitoring and clinical practice, little data is available to show the predictive value of intracranial pressure monitoring in assessment of the outcome
Majid Reza Farrokhi, Mousa Taghipour
doaj  

The effectiveness of simultaneous monitoring of intracranial pressure and cerebral perfusion pressure in patients with severe cranio-cerebral trauma

Ukrainian Neurosurgical Journal, 2011
The role of hypotension, hypoxia, intracranial hypertension and cerebral perfusion pressure (CPP) in patients with severe cranio-cerevral trauma (CCT) was observed.
Ihor Zagriychuk
doaj   +1 more source