Results 21 to 30 of about 38,659 (182)
Journal of International Medical Research, 2021 Spinal cord stimulation (SCS) has been used to treat sustained pain that is intractable despite various types of treatment. However, conventional tonic waveform SCS has not shown promising outcomes for spinal cord injury (SCI) or postamputation pain. The
Kuen Su Lee +4 more
doaj +1 more source
Ketamine Use for Successful Resolution of Post-ERCP Acute Pancreatitis Abdominal Pain
Case Reports in Anesthesiology, 2017 We report a case in which a patient with intractable pain secondary to post-endoscopic retrograde cholangiopancreatography (ERCP) acute pancreatitis is successfully treated with a subanesthetic ketamine infusion.
Suneel M. Agerwala +2 more
doaj +1 more source
Roux-en-Y longitudinal Pancreatico Jejunostomy for Pancreatic Calculi in Children
Bangabandhu Sheikh Mujib Medical University Journal, 2011 Background: Pancreatic calculi is distinctly uncommon in children and usually present wit recurrent abdominal pain. Objective: To assess the effectiveness of longitudinal pancreatico-jejunostomy in relieving intractable abdominal pain in children with ...
AKM Zahid Hossain +2 more
doaj +1 more source
Angewandte Chemie, EarlyView.Strategic incorporation of unnatural amino acids transforms macrocyclic peptides into drug‐like molecules capable of engaging challenging targets. These building blocks enhance stability, permeability, and bioavailability, accelerating the development of next‐generation peptide therapeutics.
Krishna K. Sharma +5 more
wiley +2 more sources
Multiple myeloma with intractable lumbar pain and diagnostic challenge with MRI: A case report
Radiology Case Reports, 2021 We present a 63-year-old male patient with intractable bone pain and rapidly progressive osteoporosis, who was diagnosed with multiple myeloma (MM) by CT despite normal magnetic resonance imaging (MRI) findings.
Min Jae Myung, MD +4 more
doaj +1 more source
Palliative Medicine Reports, 2021 Background: There are no universal tools to predict the necessity of high-dose opioid use for cancer-related pain. Early recognition and interventions for intractable cancer pain could minimize the distress of palliative patients. Objective: We sought to
Hidetoshi Sumimoto +9 more
doaj +1 more source
Advanced Science, EarlyView.A biomimetic doppelgänger nanosystem neutralizes extracellular inflammatory cytokines and silences intracellular pyroptosis, reprogramming pathogenic macrophages to attenuate both joint and spine degeneration. ABSTRACT Osteoarthritis (OA) and intervertebral disc degeneration (IVDD) are debilitating musculoskeletal disorders driven by shared ...
Fudong Li +9 more
wiley +1 more source
Case Reports in Neurological Medicine, 2014 Headaches and facial pain can be extremely difficult to manage for the patient and the clinician. In the medical literature, it has been suggested that the autonomic reflex plays an important role in the pathophysiology of facial neuralgia.
Foad Elahi, Kwo Wei David Ho
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Advanced Science, EarlyView.This study reveals that 5'tiRNA‐Gln interacts with hnRNPC to promote IGF1R liquid‐liquid phase separation, which drives ERK1/2 signaling activation, EMT, and breast cancer bone metastasis. These findings highlight a novel mechanism of breast cancer bone metastasis and potential therapeutic target in metastatic breast cancer.
Bingnan Wang +9 more
wiley +1 more source
Ultrasound-Guided Nerve Block with Botulinum Toxin Type A for Intractable Neuropathic Pain
Toxins, 2016 Neuropathic pain includes postherpetic neuralgia (PHN), painful diabetic neuropathy (PDN), and trigeminal neuralgia, and so on. Although various drugs have been tried to treat neuropathic pain, the effectiveness of the drugs sometimes may be limited for ...
Young Eun Moon +4 more
doaj +1 more source