Results 81 to 90 of about 49,583 (285)

Comparative investigation into the immune efficiency of the single intradermal and intramuscular delivery of foot-and-mouth disease inactivated vaccine in swine

Virus Research
Foot-and-mouth disease (FMD) is a highly contagious and economically devastating disease. Traditional intramuscular (IM) injection of inactivated FMD vaccines has been crucial for disease control, but intradermal (ID) immunization offers advantages such ...
Weijun Cao, Jingwen Li, Fan Yang, Zixiang Zhu, Wei Zhang, Haixue Zheng, Yanming Wei   +6 more
doaj   +1 more source

Humoral immunogenicity of a Coronavirus Disease 2019 (COVID-19) DNA vaccine in rhesus macaques (Macaca mulatta) delivered using needle-free jet injection.

PLoS ONE, 2023
A SARS-CoV-2 DNA vaccine targeting the spike protein and delivered by jet injection, nCOV-S(JET), previously shown to protect wild-type and immunosuppressed Syrian hamsters (Mesocricetus auratus), was evaluated via two needle-free delivery methods in ...
Alexandra Jay, Steven A Kwilas, Matthew Josleyn, Keersten Ricks, Jay W Hooper   +4 more
doaj   +1 more source

Metastatic lymph nodes in the neck of patients with T1 and T2 squamous cell carcinoma of the lower lip detected with lymphoscintigraphy [PDF]

, 2013
Aims and backgroundThe aim of our research was to use lymphoscintigraphy as a main method to confirm and detect lymph nodes in the neck, in patients with squamos cell carcinoma of lower lip which were clinically T1, T2 and N0, and to justify the use of ...
Agani, Zana, Gerqari, Idriz, Hamiti, Vjosa, Loxha, Mergime Prekazi, Salihu, Sami   +4 more
core   +1 more source

Crystal Facet‐Polysaccharide Matching in CFS‐P Nanocrystals Drives Fungal Uptake, Vacuole Destruction, and Selective Antifungal Activity

Advanced Science, EarlyView.
Facet‐engineered PVP‐capped CuFeSe2 nanocrystals exhibit potent, selective antifungal activity by strongly binding cell‐wall mannan, enabling vacuolar entry and organelle disruption. High‐index facets show superior mannan affinity, validated by theoretical calculations and experiments. CFS‐P induces vacuolar cavitation, mitochondrial abnormalities, and
Zhaohui Wang, Xiaojin Deng, Xujuan Huang, Yuhang Pan, Yao Qin, Lu Zhang, Le Xu, Tianyi Qin, Deteng Zhang, Yi Ma, Yalong Wang   +10 more
wiley   +1 more source

A Biomimetic Lubricant Captures Hyaluronic Acid In Situ to Regenerate Cartilage: From Bench to Bedside

Advanced Science, EarlyView.
(a) The outstanding lubricative properties of natural articular cartilage arise from a composite coating composed of HA, lubricin, and phospholipids at its surface. Notably, lubricin facilitates the enrichment of synovial HA onto cartilage surfaces, and HA complexes with phospholipids, a key component to maintain extremely low friction under high ...
Yongan Lin, Zijian Yan, Jiayi Chen, Xiaochao Wang, Ruibin Lin, Yunqi Fu, Zhaoying Lv, Bohui Wu, Xuewei Cao, Renjian Xie, Ming Dong, Chenxiao Zheng, Li Ren   +12 more
wiley   +1 more source

Intradermal delivery of vaccines: potential benefits and current challenges

Bulletin of the World Health Organization, 2011
Delivery of vaccine antigens to the dermis and/or epidermis of human skin (i.e. intradermal delivery) might be more efficient than injection into the muscle or subcutaneous tissue, thereby reducing the volumes of antigen.
JK Hickling, KR Jones, M Friede, D Zehrung, D Chen, D Kristensen   +5 more
doaj   +1 more source

Mycobacterium Bovis (Strain BCG) Effects on the Growth and Metastasis of a Transplantable Hamster Lung Adenocarcinoma [PDF]

, 1979
Author Institution: Department of Microbiology, and Comprehensive Cancer Center, The Ohio State UniversityThe effect of Bacillus-Calmette-Guerin (BCG) on the growth of an adenocarcinoma of the lung induced in a Syrian hamster was evaluated.
Bakaletz, Alan P., Zwilling, Bruce S.
core  

Awareness on Intradermal Injection among Dentists

Journal of Pharmaceutical Research International, 2020
An intradermal injection may be given for diagnostic purposes checking for allergy, lymphogranuloma inguinale or tuberculosis and for treating diseases like vitiligo. Due to the limited blood supply of that skin layer, medication injected into the dermis is absorbed slowly.
Dhanraj Ganapathy, Chithambara Shathviha Palaniappan   +1 more
openaire   +2 more sources

Secreted Nonstructural Protein 3 is a Pathogenic Determinant of Orbivirus

Advanced Science, EarlyView.
This study uncovers a conserved PIP2‐dependent secretory pathway of orbivirus NS3 that induces vascular leakage. Pharmacological disruption of PIP2‐NS3 interaction significantly reduces viral pathogenicity and provides protective efficacy in murine models, establishing PIP2‐mediated NS3 secretion as both a key virulence determinant and a promising ...
Junyong Guan, Dong Zhou, Ran Shao, Xing Liu, Jin Peng, Yingran Huang, Shuhui Qi, Cankun Xi, Menghang Wang, Bin Sun, Yinglin Qi, Xin Yin   +11 more
wiley   +1 more source

Intradermal Injection in Balding Region Versus Intramuscular Injection in Surrounding Muscles: A Split-Scalp, Randomized Trial on BoNT for Androgenetic Alopecia

Dermatology and Therapy
Introduction Recent advancements in androgenetic alopecia (AGA) treatment have highlighted the efficacy of botulinum toxin (BoNT). However, inconsistencies in injection sites and depths warrant attention.
Jiaqi Li, Shu Zhang, Wenbin Zhao, Fengjuan Yang, Maolin Liu, Xiaohua Li, Xian Jiang   +6 more
doaj   +1 more source