Results 81 to 90 of about 51,047 (183)

Expression of the stem cell markers NANOG and SOX2 in the cervical squamous carcinogenesis

open access: yesRadiology and Oncology
The aim of the present study was to assess a diagnostic potential of stem cell markers NANOG and SOX2 for classifying cervical squamous intraepithelial lesions (SILs)/cervical intraepithelial neoplasia (CIN).
Koren Miha   +4 more
doaj   +1 more source

Loss to follow‐up in patients diagnosed with or treated for low‐ and high‐grade squamous intraepithelial lesions: A comparison of general practitioner‐ and gynecologist‐led surveillance

open access: yesActa Obstetricia et Gynecologica Scandinavica, EarlyView.
Follow‐up by general practitioners after LSIL or treated HSIL was associated with higher loss to follow‐up rates compared with gynecologist‐led care. Loss to follow‐up was 38.1% versus 16.6% for LSIL at 12 months and 44.3% versus 24.1% for treated HSIL at 24 months.
Lieke van de Kam   +4 more
wiley   +1 more source

Active surveillance of cervical intraepithelial neoplasia and adverse pregnancy outcomes: A register‐based cohort study

open access: yesActa Obstetricia et Gynecologica Scandinavica, EarlyView.
Active surveillance for cervical intraepithelial neoplasia grade 2 is not associated with increased risks of adverse pregnancy outcomes compared to large loop excision of the transformation zone. Abstract Introduction Previous studies have suggested that human papillomavirus (HPV) and HPV‐related disease may be associated with increased risk of adverse
Kirstine Kold Katholm   +6 more
wiley   +1 more source

Targeting KRAS for cancer therapy

open access: yesBritish Journal of Pharmacology, EarlyView.
In recent years, therapeutics targeted against KRAS proto‐oncogene GTPase (KRAS)‐mutant cancers have seen significant progress. Herein we outline the biology and epidemiology of KRAS alterations at the lineage and allele levels, reviewing the clinical evidence for KRASG12C inhibition from the discovery of the recessive switch pocket to sotorasib ...
Jianlong Jia   +4 more
wiley   +1 more source

Bile‐Derived Exosomal miR‐196a/‐196b as Diagnostic Biomarkers Associated With Tumor Progression in Biliary Tract Cancer

open access: yesCancer Science, EarlyView.
Bile‐derived exosomal miR‐196a and miR‐196b are identified as novel biomarkers for biliary tract cancer. Serum miR‐196a levels are significantly elevated in advanced disease with metastasis, while both miRNAs contribute to tumor progression by promoting cancer cell proliferation and invasion.
Naotaka Kugiyama   +20 more
wiley   +1 more source

HPV42 – a human papillomavirus classified as a low‐risk type with oncogenic potential

open access: yesJDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Summary Human papillomavirus (HPV) type 42 is a rare HPV type currently classified as “low‐risk” and belongs to the alpha genus. It has primarily been detected in benign vulvar papillomas and is predominantly associated with benign lesions such as anogenital warts.
Sven Niklas Burmann   +7 more
wiley   +1 more source

The Varying Faces of Vulvar Neoplasia

open access: yesIndian Dermatology Online Journal
Vulvar neoplasia is on the rise and patients often present to dermatologists with lesions of varying morphology associated with pruritus, burning sensation, or pain.
Kavitha Athota   +2 more
doaj   +1 more source

The emerging role of the Hippo signaling pathway in interorgan crosstalk

open access: yesThe FEBS Journal, EarlyView.
Hippo signaling functions as a central hub of interorgan communication. Systemic cues from the gut, adipose tissue, and skeletal muscle—including hormones, metabolites, and microbial signals—regulate YAP/TAZ activity in a tissue‐ and context‐dependent manner.
Gahyeon Song   +2 more
wiley   +1 more source

Correction of cyto-biochemical process disorders of cervical mucosa with cervical intraepithelial neoplasia [PDF]

open access: yesРМЖ. Мать и дитя, 2018
Correction of cyto-biochemical process disorders of cervical mucosa with cervical intraepithelial neoplasia I.O. Borovikov, E.E. Gerasimenko, H.I.
Borovikov I.O.   +2 more
doaj  

Anal Cancer Screening and High‐Resolution Anoscopy: What Surgeons Should Know

open access: yes
ANZ Journal of Surgery, EarlyView.
Matthew Joseph Marino   +4 more
wiley   +1 more source

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