Results 101 to 110 of about 51,047 (183)

Diagnostic accuracy of phosphatase and tensin homolog loss in differentiating between atypical endometrial hyperplasia/endometrioid intraepithelial neoplasia and non‐atypical endometrial hyperplasia: A systematic review and meta‐analysis

International Journal of Gynecology &Obstetrics, Volume 174, Issue 2, Page 630-642, August 2026.
Abstract Background Accurate distinction between atypical endometrial hyperplasia/endometrioid intraepithelial neoplasia (AH/EIN) and non‐atypical endometrial hyperplasia (EH) determines whether patients require hysterectomy or can be managed conservatively.
Kristina Shcherbatiuk, Steffi Bultmann, Thomas Karn, Khayal Gasimli, Peter Wild, Sven Becker, Morva Tahmasbi Rad   +6 more
wiley   +1 more source

Aggressive squamous cell carcinomas arising from mucosal lichen planus: A report of three cases

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Neda Cramer, Dagmar Wilsmann‐Theis, Michael P. Schön, Jörg Wenzel, Julia Gallwas, Rotraut Mössner   +5 more
wiley   +1 more source

The impact of physiological oxidants on triggering amyloid formation of the cell cycle regulator protein p16INK4A

Protein Science, Volume 35, Issue 8, August 2026.
Abstract The tumor suppressor protein p16INK4a plays a key role in cell cycle control and is frequently inactivated in human cancers. We previously discovered that oxidation of its single cysteine residue induces a structural transition from the functional monomeric form into inactive amyloid fibrils.
Briana R. Smith, Nicholas J. Magon, Aakriti Sethi, Shelby G. Gray, Sarah G. Heath, Vanessa K. Morris, Christoph Göbl   +6 more
wiley   +1 more source

Deep Understanding of Vaginal Microbiota in HPV‐Related Diseases From a Multi‐Omics Perspective

VIEW Medicine, Volume 1, Issue 1, August 2026.
Current understanding of the vaginal microbiota and roles of critical vaginal bacteria, including Lactobacillus and anaerobic pathogens, in human papillomavirus (HPV) infection and HPV‐related diseases from a multi‐omics perspective. ABSTRACT There is a large number of microorganisms in the human body, which are inseparable from human health.
Jianxujie Zheng, Qing Cong, Ling Lin, Liang Qiao   +3 more
wiley   +1 more source

Assessing the clinical value of cervical biopsies in individuals with transformation zone type 3 at colposcopy: A cross‐sectional study

Acta Obstetricia et Gynecologica Scandinavica, Volume 105, Issue 8, Page 1597-1606, August 2026.
In transformation zone type 3, a systematic multiple biopsy protocol improved CIN2+ detection, particularly in high‐grade referrals, whereas yield remained limited in low‐grade referral cases. DSI‐assisted colposcopy did not increase biopsy sensitivity’.
Vibe Munk Bertelsen, Berit Bargum Booth, Mette Tranberg, Lone Kjeld Petersen, Pinar Bor   +4 more
wiley   +1 more source

Cost‐effectiveness of risk‐stratified screening for cervical cancer in cohorts vaccinated against human papillomavirus with moderate vaccination coverage

International Journal of Cancer, Volume 159, Issue 2, Page 389-400, 15 July 2026.
What's new? Effective cervical cancer prevention centers around screening and testing for human papillomavirus (HPV) infection. With birth cohorts of HPV‐vaccinated women now reaching screening‐eligible ages, however, the best means to maintaining cost‐effective cervical cancer screening is unclear.
Tiago M. de Carvalho, Johannes Berkhof, Johannes A. Bogaards   +2 more
wiley   +1 more source

Exfoliative cytology as a tool in the preinvasive anal lesions diagnosis

Medisur
The anal cancer increase in high-risk populations stimulates the implementation of protocols to carry out early diagnosis, as well as the monitoring of high-grade anal intraepithelial neoplasia as a precursor lesion.
Javier Martínez Navarro
doaj  

Dynamics of the association between circulating levels of miRNA and pancreatic cancer risk through the years prior to pancreatic cancer diagnosis

International Journal of Cancer, Volume 159, Issue 2, Page 526-537, 15 July 2026.
What's new? Early diagnosis is critical for improving pancreatic ductal adenocarcinoma prognosis, but few biomarkers currently exist. In a case–control study of 1,307 pancreatic cancer cases and matched pairs nested in prospective cohort studies, 13 miRNA–cancer associations were found to change during the blood‐draw‐to‐diagnosis time window.
Hui Cai, Veronica Wendy Setiawan, Xingyi Guo, Jie Wu, Rachael Stolzenberg‐Solomon, Yu‐Tang Gao, Jordan Berlin, Fei Ye, Qiuyin Cai, Wei Zheng, Xiao‐Ou Shu   +10 more
wiley   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, Volume 20, Issue 7, Page 1726-1741, July 2026.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Androgen Receptor‐Induced Lactoferrin Accelerates Prostate Tumorigenesis Through Modulating Ferroptosis

Advanced Science, Volume 13, Issue 37, 3 July 2026.
This study demonstrates that transcription factor androgen receptor (AR) directly binds the LF promoter, driving lactoferrin overexpression to promote ferritin (FTH1/FTL) upregulation and inhibit p53‐ALOX12‐mediated ferroptosis in prostate cancer. Lactoferrin could be a new potential therapeutic target in prostate cancer.
Can Liu, Qiu Peng, Xiaoyue Zhang, Zhengshuo Li, Yangge Wu, Yuqing Wen, Run Zheng, Shuanglong Wu, Chenfei Zhou, Zhengyu Hu, Lanjun Shu, Xinyi Ma, Qiuyang Li, Ya Ma, Chunlin Ou, Ming Zhao, Songqing Fan, Lingyu Wei, Jian Ma   +18 more
wiley   +1 more source