Results 101 to 110 of about 51,227 (230)

Prevention of Myc‐Driven Prostate Cancer in Mice by Oral Administration of Sulforaphane

Molecular Carcinogenesis, Volume 65, Issue 9, Page 1052-1062, September 2026.
ABSTRACT Prevention is desirable to reduce suffering and death from prostate cancer. However, a clinical‐grade intervention for the prevention of this malignancy is still lacking. This study was undertaken to determine the feasibility of prostate cancer prevention by broccoli constituent sulforaphane (SFN) because epidemiological studies have suggested
Krishna B. Singh, Eun‐Ryeong Hahm, Bruce L. Jacobs, Shivendra V. Singh   +3 more
wiley   +1 more source

Results of loop diathermy conization as diagnostic and therapeutic procedure

Acta Médica del Centro, 2014
Introduction: currently broadcasts the use of diathermy handles for the treatment of premalignant lesions of the neck. Objective: to present the results of loop diathermy conization in cervical premalignant lesions.
Yarima Bravo Torres, Yordayka Elda Rivero Ramírez, Yoel Cardet Niebla, Armando Eugenio Iglesias Yera, Fernando Machado Rojas, Sandi Jiménez Puñales   +5 more
doaj  

Infection by the human papillomavirus in teenagers sexually active: clinic and subclinic manifestations

São Paulo Medical Journal
This research studies the association of the cervical condyloma with the intraepithelial neoplasia, during sex activity, pregnancy, diagnose methods, cytology and colposcopy in teenagers.
Sophie Derchain, Jessé de Paula Neves-Jorge, Liliana Andrade, Aarão Mendes Pinto-Neto, João Pinto e Silva   +4 more
doaj   +1 more source

Anal intraepithelial neoplasia [PDF]

Journal of British Surgery, 1999
openaire   +2 more sources

Prostate Cancer Development, Progression, and Therapy

MedComm – Oncology, Volume 5, Issue 3, September 2026.
This review provides an integrated overview of prostate cancer development, progression, and therapy, spanning historical milestones, molecular mechanisms, advanced research models, and emerging therapeutic strategies. It highlights recent advances in precision diagnosis, lineage plasticity, therapy resistance, and next‐generation treatments for ...
Xin Jin, Zicheng Xiao, Zexian Ding, Wei Li, Ruijiang Zeng, Yujun Shuai, Weimin Ci, Dan Xia, Xu Zhang, Haojie Huang   +9 more
wiley   +1 more source

Knowledge gaps in tubular gut tumours: a critical appraisal of the 6th edition of the World Health Organization classification of tumours

The Journal of Pathology, Volume 270, Issue 1, Page 4-22, September 2026.
Abstract Gastrointestinal cancer is a global health problem. In the new 6th edition of the World Health Organization Classification of Tumours (WCT) of the Digestive System, updated evidence and guidance is provided for the aetiology, pathogenesis, diagnosis, classification, grading, staging and prognosis of these tumours.
Iris D Nagtegaal, Elizabeth A Montgomery, Alexandros D Polydorides, Anthony J Gill, Motohiro Kojima, Mark J Arends   +5 more
wiley   +1 more source

Comparison of Cervical Screening at 6‐ and 12‐Weeks Postnatal: A Paired‐Sample Feasibility Study

BJOG: An International Journal of Obstetrics &Gynaecology, Volume 133, Issue 10, Page 1857-1865, September 2026.
ABSTRACT Objective Feasibility of a paired‐sample study comparing cervical screening and urine self‐sampling at 6‐ and 12‐weeks postnatal. Design Paired‐sample feasibility study. Setting Acute hospital. Population or Sample Females within 6 weeks of childbirth. Methods Paired‐sample study comparing cervical screening and high‐risk human papillomavirus (
Victoria A. Cullimore, Tessa Dean, Kim Chu, Adam Brentnall, Karin Denton, Katherine Hunt, Alexandra Sargent, Laura Johns, Katharine Edey, Sarah L. Coleridge, Jane Borley, Rebecca Newhouse, Holly Baker‐Rand, Lorna McWilliams, Emma J. Davidson, Jo Morrison   +15 more
wiley   +1 more source

Balancing diagnostic accuracy and cost in the follow‐up of histological low‐grade squamous intraepithelial lesions

Acta Obstetricia et Gynecologica Scandinavica, Volume 105, Issue 9, Page 1871-1878, September 2026.
Primary follow‐up of histological LSIL can shift from colposcopy to liquid‐based co‐testing without missed cancers, as the incremental cost per additional HSIL+ detected is unjustified. Abstract Introduction Primary cervical screening with testing for human papillomavirus (HPV) brings increased detection of women with low‐grade squamous intraepithelial
Riina Aarnio, Vasudha Ahuja, Linda Ryen, Lovisa Bergengren   +3 more
wiley   +1 more source

Cervical Cytokine Profile in High‐Grade Squamous Intraepithelial Lesions

Cytopathology, Volume 37, Issue 5, Page 523-530, September 2026.
Hypothetical mechanism of immune modulation in HSIL associated with high‐risk HPV infection, based on observed cytokine suppression. The diagram illustrates impaired Th1 responses, reflected by reduced production of IL‐2 and TNF, which may compromise the activation and cytotoxic function of CD8+ T cells and NK cells, facilitating immune evasion.
Talles Henrique de Araújo Pontes, Amaxsell Thiago Barros de Souza, Carolina de O. Mendes‐Aguiar, Maria do Perpétuo Socorro Nobre Medeiros e Silva, Juliana Dantas de Araújo Santos Camargo, George Alexandre Lira, Ricardo Ney Cobucci, Deyse de Souza Dantas, Janaina Cristiana de Oliveira Crispim   +8 more
wiley   +1 more source

Unveiling the molecular profile of adenosquamous gallbladder carcinoma: characterization of a Caucasian cohort

Histopathology, Volume 89, Issue 3, Page 442-455, September 2026.
GBASCs are MMRp tumours, exhibiting minimal HER2 overexpression and elevated PD‐L1 expression compared to adenocarcinomas. Especially in metastatic and TP53‐wild type tumours, GBASCs can express CLDN18, albeit limited to the glandular component. Their genomic profile resembles that of adenocarcinomas with an enrichment in alterations on PIK3CA, PTEN ...
Jessica Gasparello, Valentina Angerilli, Mario Domenico Rizzato, Edoardo Maffii, Carlotta Ceccon, Matilde Callegarin, Marianna Sabbadin, Monia Niero, Luisa Toffolatti, Francesca Bergamo, Paola Parente, Luca Mastracci, Federica Grillo, Alessandro Vanoli, Paola Mattiolo, Claudio Luchini, Angelo Paolo Dei Tos, Umberto Cillo, Giacomo Zanus, Sara Lonardi, Matteo Fassan   +20 more
wiley   +1 more source