Results 111 to 120 of about 51,227 (230)

Spatial transcriptomics reveals clonal relationships between intraductal carcinoma and adjacent invasive prostate cancer

Histopathology, Volume 89, Issue 3, Page 429-441, September 2026.
Spatial transcriptomics of six prostate samples reveals a close clonal relationship between high‐grade Prostatic Intraepithelial Neoplasia (HGPIN), Intraductal carcinoma (IDC) and adjacent invasive glands. In three samples, adjacent invasive glands had more copy number variants than HGPIN and IDC. Adjacent invasive glands were also placed at the end of
Hridya Harikumar, Myrthe de Waard‐van Baardwijk, Marit de Haan, Gregory van Beek, Karishma Lila, Martin E van Royen, Thierry PP van den Bosch, Mathijs A Sanders, Eric Bindels, Andrew Stubbs, Geert JLH van Leenders   +10 more
wiley   +1 more source

Risk stratification and anal cancer screening in immunocompetent women with genital HPV: Value of multicentric HSIL and performance of HPV‐based screening

International Journal of Cancer, Volume 159, Issue 4, Page 1017-1027, 15 August 2026.
What's new? Anal squamous cell carcinoma (ASCC) incidence is increasing, with most cases occurring in immunocompetent women. ASCC risk is linked in particular to genital human papillomavirus (HPV) infection and HPV‐associated high‐grade squamous intraepithelial lesions (HSILs).
Isabel Matas, Aureli Torné, Adela Saco, Cristina Martí, Ada Cardiel, Natalia Rakislova, Lorena Marimon, Ariel Glickman, Ingrid Victoria, Silvia Alós, Jesús Lopez‐Diaz, Pere Fusté, Jaume Ordi, Marta del Pino   +13 more
wiley   +1 more source

Exfoliative cytology as a tool in the preinvasive anal lesions diagnosis

Medisur
The anal cancer increase in high-risk populations stimulates the implementation of protocols to carry out early diagnosis, as well as the monitoring of high-grade anal intraepithelial neoplasia as a precursor lesion.
Javier Martínez Navarro
doaj  

Nationwide Study on the Cervical Cancer Screening Pathway in Estonia

International Journal of Cancer, Volume 159, Issue 4, Page 883-895, 15 August 2026.
Cervical cancer remains a significant burden despite being preventable, largely due to inadequate screening participation and poor follow‐up of high‐risk women. Here, the authors investigated follow‐up rates among women who tested positive for high‐risk human papillomavirus (hr‐HPV) infection in primary screening in Estonia. Data show that more than 57
Aleksandra Šavrova, Helen Jakoby, Anna Tisler, Kaire Innos, Ülo Maiväli, Jana Jaal, Anneli Uusküla   +6 more
wiley   +1 more source

Incidence of penile cancer in Southeast Wales: A 15‐year retrospective review

BJUI Compass, Volume 7, Issue 8, August 2026.
Abstract Objectives This study aims to determine the 15‐year incidence of penile cancer (PeCa) and penile intraepithelial neoplasia (PeIN) in Southeast Wales, evaluate regional variation and compare findings to UK and global rates. Materials and Methods A retrospective review was conducted of all PeCa and PeIN cases diagnosed between January 2009 and ...
Joseph Latham, Oliver Lane, David Gower, Adrian Sale, Anthony Shanahan, Mohammed Ali, Gareth Brown   +6 more
wiley   +1 more source

Large Anogenital Bowen Disease Misdiagnosed as Chronic Eczema for Nine Years: A Case Report Highlighting the Importance of Early Biopsy

Clinical Case Reports, Volume 14, Issue 8, August 2026.
ABSTRACT Persistent treatment‐resistant anogenital plaques should not be repeatedly managed as chronic eczema without histopathological confirmation. Early biopsy of atypical or non‐resolving lesions facilitates timely diagnosis of Bowen disease, prevents prolonged diagnostic delay, and enables treatment before progression to invasive squamous cell ...
Shiwani Sharma Acharya, Sanket Bishokarma, Uma Giri   +2 more
wiley   +1 more source

Integrin α5β1 in pancreatic ductal adenocarcinoma: Tumour‒stroma crosstalk, hypoxia and therapeutic targeting

Clinical and Translational Medicine, Volume 16, Issue 8, August 2026.
ITGA5/integrin α5β1 promotes PDAC progression by integrating fibronectin‐dependent adhesion, hypoxia‐associated ECM remodelling, pancreatic stellate cell/cancer‐associated fibroblast activation, desmoplasia and tumour‒stroma crosstalk. These processes contribute to impaired drug delivery and therapeutic resistance.
Chenzhe Ma, Yingying Wang, Yumin Li
wiley   +1 more source

Comparative Performance of Pap Smear and Colposcopy in Cervical Cancer Screening Among Women With Abnormal Cervical Findings in Central India: A Prospective Observational Study

Health Science Reports, Volume 9, Issue 8, August 2026.
ABSTRACT Background Cervical cancer remains a leading cause of death among women worldwide, particularly in low‐ and middle‐income countries. This study aimed to evaluate and compare the effectiveness of Pap smear and colposcopy in detecting cervical abnormalities in women with unhealthy cervices and correlate findings with biopsy results.
Bhukya Priyanka, Bhakti Gurjar, Shreya Dahiwade, Gaurang Narayan, Calvin R. Wei, Babar Ali, Aymar Akilimali   +6 more
wiley   +1 more source

Extended HPV typing as an efficient alternative within HPV‐based screening programs

International Journal of Cancer, Volume 159, Issue 3, Page 638-644, 1 August 2026.
What's New? Extended high‐risk human papillomavirus (hrHPV) typing holds promise for improving cervical intraepithelial neoplasia grade 3 (CIN3) detection, particularly as vaccinated cohorts may shift the prevalence of oncogenic HPV types. The authors of this study evaluated extended hrHPV genotyping within a public screening program involving women ...
Joacim Meneses‐León, Berenice Rivera‐Paredez, Sonia Hernández‐Salazar, Leticia Torres‐Ibarra, Martha Carnalla, Leith León‐Maldonado, Rubí Hernández‐López, José Damián Cadena‐Fiscal, Anna B. Moscicki, Manuel Quiterio‐Trenado, Eduardo Lazcano‐Ponce, Jorge Salmerón   +11 more
wiley   +1 more source

Detection of HPV DNA in Cervical Intraepithelial Neoplasia Using In Situ Hybridization. [PDF]

J Clin Med
Przybylski M, Millert-Kalińska S, Pruski D, de Mezer M, Krzyżaniak M, Jach R, Żurawski J, Kurzawa P.   +7 more
europepmc   +1 more source