Results 51 to 60 of about 1,647 (123)

Base Flipping of the Thymine Dimer in Duplex DNA^§

, 2016
Exposure of two adjacent thymines in DNA to UV light of 260−320 nm can result in the formation of the cis,syn-cyclobutane pyrimidine dimer (CPD). The structure of DNA containing an intrahelical CPD lesion has been previously studied experimentally and ...
Alan Grossfield (1855390), Lauren L. O'Neil (2473039), Olaf Wiest (105849)   +2 more
core   +1 more source

Intermolecular Interactions in Photodamaged DNA from Density Functional Theory Symmetry‐Adapted Perturbation Theory

, 2011
The intermolecular interactions of the photodamaged cyclobutane pyrimidine dimer (CPD) lesion with adjacent nucleobases in the native intrahelical DNA double strand are investigated at the level of density functional theory symmetry-adapted perturbation ...
Sadeghian, Keyarash, Marco Bocola, Martin Schütz, Schütz, Martin, Keyarash Sadeghian, Bocola, Marco   +5 more
core   +1 more source

Mapping the recognition pathway of cyclobutane pyrimidine dimer in DNA by Rad4/XPC. [PDF]

Nucleic Acids Res, 2023
Jakhar N, Prabhakant A, Krishnan M.
europepmc   +1 more source

Improving coiled-coil stability by optimizing ionic interactions

, 2002
Alpha-helical coiled coils are a common protein oligomerization motif stabilized mainly by hydrophobic interactions occurring along the coiled-coil interface.
Lustig, A., Burkhard, P., Ivaninskii, S., Ivaninskii S, Lustig A, Burkhard P, Peter Burkhard, Ariel Lustig, Sergei Ivaninskii   +8 more
core   +1 more source

Influence of the environment in the conformation of alpha-helices studied by protein database search and molecular dynamics simulations.

, 2002
The influence of the solvent on the main-chain conformation (phi and Psi dihedral angles) of alpha-helices has been studied by complementary approaches. A first approach consisted in surveying crystal structures of both soluble and membrane proteins. The
Pardo, Leonardo, Olivella, Mireia, Deupi, Xavier, Govaerts, Cédric   +3 more
core   +1 more source

Molecular Dynamics Simulations of the Adenosine A2a Receptor in POPC and POPE Lipid Bilayers: Effects of Membrane on Protein Behavior

, 2016
Analysis of 300 ns (ns) molecular dynamics (MD) simulations of an adenosine A2a receptor (A2a AR) model, conducted in triplicate, in 1-palmitoyl-2-oleoylphosphatidylcholine (POPC) and 1-palmitoyl-2-oleoylphosphatidylethanolamine (POPE) bilayers reveals ...
Hui Wen Ng (1456123), Stephen W. Doughty (1456120), Charles A. Laughton (1842862)   +2 more
core   +1 more source

Intrahelical side chain interactions in α-helices: poor correlation between energetics and frequency

, 1998
Polypeptide sequences in proteins may increase their tendency to adopt helical conformations in several ways. One is the recruiting of amino acid residues with high helical propensity.
J Sancho, J Fernández-Recio
core   +1 more source

Conformation of the Group II Intron Branch Site in Solution

, 2016
Group II introns are multidomain ribozymes that catalyze their own removal from pre-mRNA. The nucleophile for the first cleavage step is the 2‘OH of a specific adenosine within domain 6 (D6), called the branch site.
Samuel H. Crayton (2645893), Jörg C. Schlatterer (527439), Nancy L. Greenbaum (7466)   +2 more
core   +1 more source

Crystallinity and Melting of Functionalized Poly(2,6-dimethyl-1,4-phenylene) oxide (PPO)

Co-crystalline and nanoporous-crystalline poly(2,6-dimethyl-1,4-phenylene) oxide (PPO) phases can be achieved for randomly functionalized PPO. In fact, WAXD, DSC, and FTIR studies show the presence of remarkable crystallinity in PPO films with ...
Nagendra B., Tarallo O., Daniel C., Guerra G., Acocella M. R., Syed S., Rizzo P.   +6 more
core   +1 more source

Kinetic Resolution of the Atomic 3D Structures Formed by Ground and Excited Conformational States in an RNA Dynamic Ensemble. [PDF]

J Am Chem Soc, 2023
Roy R, Geng A, Shi H, Merriman DK, Dethoff EA, Salmon L, Al-Hashimi HM.   +6 more
europepmc   +1 more source