Results 81 to 90 of about 1,647 (123)

Next-generation chemogenetic inhibition using a brain-permeant non-prescription agent. [PDF]

Signal Transduct Target Ther
Devenish SO, Patel SD, Ussingkær LV, Almeida Silva LF, Goff O, Richardson A, Mobbs JI, Venugopal H, Thal DM, Kullmann DM.   +9 more
europepmc   +1 more source

Mechanisms of search for specific sites in DNA by DNA-binding proteins. [PDF]

Biochem Biophys Rep
Lukina MV, Fedorova OS, Chernonosov AA, Koval VV.   +3 more
europepmc   +1 more source

Identification and Characterization of a Phenyl(trifluoro-methyl)-pyrimidine Positive Allosteric Modulator of the Secretin Receptor. [PDF]

Membranes (Basel)
Harikumar KG, Dengler DG, Borrega Roman L, Ardecky R, Sergienko EA, Miller LJ.   +5 more
europepmc   +1 more source

Predicting compounds that interact with the 2 known agonist-induced conformations of the human β1-adrenoceptor. [PDF]

Mol Pharmacol
Baker JG, Lim VJY, Proudman RGW, Giese FNZ, Kolb P.   +4 more
europepmc   +1 more source

Small molecule inhibitor of orphan GPCR dimerization improves host defense and blood pressure control in mice. [PDF]

J Clin Invest
Kwon J, Persechino M, Shao J, Shamsara J, Spitznagel B, Salwig I, Sanda M, Offermanns S, Kolb P, Wettschureck N.   +9 more
europepmc   +1 more source

U2 snRNP recognizes the branch site through a loaded-spring strand-invasion mechanism. [PDF]

Nucleic Acids Res
Pokorná P, Pena V, Magistrato A.
europepmc   +1 more source

Diverse regulation of functional dimerization of a sugar transporter by different interfacial lipids. [PDF]

Nat Commun
Zhang Y, Zhao W, Duan M, Shen Y, Li J, Xie H, Tong Q, Zhao Y, Yang J.   +8 more
europepmc   +1 more source

Intracellular Allosteric Antagonist of the Olfactory Receptor OR51E2. [PDF]

Mol Pharmacol
Abaffy T, Fu O, Harume-Nagai M, Goldenberg JM, Kenyon V, Kenakin T.   +5 more
europepmc   +1 more source

Flexibility of the TRMT10C N-Terminal Domain Helix Explored by Molecular Dynamics Simulations. [PDF]

J Phys Chem B
Hoang GL, Rossetti G, Tisné C, Carloni P.   +3 more
europepmc   +1 more source

Folded-state compatibility and unfolded-state constraint govern staple-based stabilization: guidelines from a coiled-coil model. [PDF]

RSC Chem Biol
Hatfield SC, Mattingley AN, Sujeta KK, Humphrey LD, Crook T, Aranda H, Freckleton CH, Clayson JV, Renstrom C, Price JL.   +9 more
europepmc   +1 more source