Results 141 to 150 of about 38,611 (262)

Standardized Approach for Laparoscopic Hemispheric Liver Resection for Segments 7 and 8

DEN Open, Volume 6, Issue 1, April 2026.
ABSTRACT Background We investigated whether the standardized “can‐opener method” surgical technique is an adequate surgical procedure for hemispheric hepatectomy in segments 7 and 8. Methods Forty‐two patients who underwent laparoscopic hemispheric liver resection for segments 7 and 8 using our standardized surgical technique were enrolled.
Ryoichi Miyamoto, Masahiro Shiihara, Mitsuru Watanabe, Jiro Shimazaki, Mitsugi Shimoda, Shuji Suzuki   +5 more
wiley   +1 more source

Efficacy of Drainage Combining Endoscopic Retrograde Cholangiopancreatography With Endoscopic Ultrasound‐guided Biliary Drainage for Difficult‐to‐Control Cholangitis in Patients With Hilar Cholangiocarcinoma

DEN Open, Volume 6, Issue 1, April 2026.
ABSTRACT Objectives Hilar cholangiocarcinoma often results in repeated early stent dysfunction and difficult‐to‐control cholangitis after drainage using endoscopic retrograde cholangiopancreatography (ERCP). In this study, we evaluated the effectiveness of additional drainage using endoscopic ultrasound‐guided biliary drainage (EUS‐BD) in patients with
Tomoki Ogata, Yusuke Kurita, Takamitsu Sato, Shin Yagi, Yu Honda, Takeshi Iizuka, Sho Hasegawa, Kunihiro Hosono, Noritoshi Kobayashi, Itaru Endo, Kensuke Kubota, Masato Yoneda, Atsushi Nakajima   +12 more
wiley   +1 more source

Phase 2 study of combination SPI-1620 with docetaxel as second-line advanced biliary tract cancer treatment [PDF]

, 2017
A Rai, AG Tolcher, AX Zhu, Caio Max S Rocha-Lima, David Portnoy, DP Brooks, E Gabriela Chiorean, E Suzuki, J Albores-Saavedra, J Nelson, J Valle, JE Rogers, JF Guion-Dussere, Jitendra Gandhi, L Goyal, M Yanagisawa, Manik Amin, NV Rajeshkumar, NV Rajeshkumar, P Papakostas, R Pazdur, Richard Kim, RK Jain, RL Siegel, S He, SC Lee, SY Oh, T Sasaki, T Walter, Tao Song, William P Harris   +30 more
core   +3 more sources

A comparison of trends in mortality from primary liver cancer and intrahepatic cholangiocarcinoma in Europe [PDF]

, 2017
Background To update and compare mortality from primary liver cancer (PLC) and intrahepatic cholangiocarcinoma (ICC) in Europe in 1990-2010. Materials and methods We used data from the World Health Organization (WHO) to compute age-standardized (world ...
Bertuccio, P., Bosetti, C., Decarli, A., La Vecchia, C., Levi, F., Negri, E.   +5 more
core  

Comparison of Endoscopic Ultrasound‐guided Tissue Acquisition and Percutaneous Liver Biopsy for Diagnosing Focal Liver Lesions: A Retrospective Single‐Center Study

DEN Open, Volume 6, Issue 1, April 2026.
ABSTRACT Background and Aim Accurate diagnosis of focal liver lesions (FLLs) is crucial for determining the appropriate treatment strategies. Although percutaneous liver biopsy (PLB) is the standard diagnostic procedure, it has limitations, particularly for difficult‐to‐access lesions.
Kei Yane, Keita Seto, Yuki Ikeda, Kotaro Morita, Mayu Shimizu, Koki Yoshida, Sota Hirokawa, Tetsuya Sumiyoshi, Michiaki Hirayama, Hitoshi Kondo   +9 more
wiley   +1 more source

Macro CD5L+ deteriorates CD8+T cells exhaustion and impairs combination of Gemcitabine-Oxaliplatin-Lenvatinib-anti-PD1 therapy in intrahepatic cholangiocarcinoma

Nature Communications
Intratumoral immune status influences tumor therapeutic response, but it remains largely unclear how the status determines therapies for patients with intrahepatic cholangiocarcinoma.
Jia-Cheng Lu, Lei-Lei Wu, Yi-Ning Sun, Xiao-Yong Huang, Chao Gao, Xiao-Jun Guo, Hai-Ying Zeng, Xu-Dong Qu, Yi Chen, Dong Wu, Yan-Zi Pei, Xian-Long Meng, Yi-Min Zheng, Chen Liang, Peng-Fei Zhang, Jia-Bin Cai, Zhen-Bin Ding, Guo-Huan Yang, Ning Ren, Cheng Huang, Xiao-Ying Wang, Qiang Gao, Qi-Man Sun, Ying-Hong Shi, Shuang-Jian Qiu, Ai-Wu Ke, Guo-Ming Shi, Jian Zhou, Yi-Di Sun, Jia Fan   +29 more
doaj   +1 more source

Distal Bile Duct Metastasis From Rectal Cancer: The Diagnostic Contribution of Intraductal Ultrasonography

DEN Open, Volume 6, Issue 1, April 2026.
ABSTRACT A 49‐year‐old male developed liver dysfunction during chemotherapy for rectal cancer located in the rectosigmoid region. Although magnetic resonance cholangiopancreatography initially indicated sclerosing cholangitis, endoscopic retrograde cholangiopancreatography and intraductal ultrasonography revealed multiple non‐contiguous intraductal ...
Shinji Monoe, Ryo Nishio, Arihiro Nakano, Yu Yasue, Takahiro Yamashita, Hitoshi Iwata   +5 more
wiley   +1 more source

A Case of Obstructive Jaundice due to Bile Duct Tumor Thrombus of Hepatocellular Carcinoma Diagnosed by Peroral Cholangioscopy

DEN Open, Volume 6, Issue 1, April 2026.
Abstract While hepatocellular carcinoma (HCC) often invades the portal or hepatic vein to form tumor thrombus, tumor thrombus in the bile duct is rare. In such cases, differentiation from intrahepatic cholangiocarcinoma is difficult, and the tumor often appears as a smooth, yellowish‐white, polypoid mass within the bile duct lumen.
Keisuke Kinoshita, Mizuki Endo, Tomoko Tokumaru, Tomoko Saito, Takuro Uchida, Masao Iwao, Mie Arakawa, Kazuhisa Okamoto, Masaaki Kodama, Kazunari Murakami   +9 more
wiley   +1 more source

Scheduled Inside Plastic Stent Exchange Prevents Cholangitis and Reduces Unplanned Hospitalization in Patients With Unresectable Malignant Hilar Biliary Obstruction

DEN Open, Volume 6, Issue 1, April 2026.
ABSTRACT Objectives To prevent cholangitis in patients with unresectable malignant hilar biliary obstruction (MHBO), we recently implemented scheduled inside plastic stent (IS) exchange every 2–4 months. This study aimed to evaluate whether this strategy prevents cholangitis onset and reduces unplanned hospitalizations without increasing adverse events.
Joji Muramatsu, Kazuma Ishikawa, Norito Suzuki, Tomohiro Kubo, Makoto Yoshida, Ginji Omori, Ryo Ito, Shogo Miura, Kohichi Takada   +8 more
wiley   +1 more source

Five Cases of Hepatic Mesenchymal Tumors Diagnosed by Endoscopic Ultrasound‐Guided Tissue Acquisition

DEN Open, Volume 6, Issue 1, April 2026.
ABSTRACT Percutaneous biopsy remains the gold standard for diagnosing focal liver lesions; however, endoscopic ultrasound‐guided tissue acquisition (EUS‐TA) has recently emerged as a promising alternative. Although its diagnostic performance is favorable, most available evidence has focused on epithelial tumors, and reports on mesenchymal tumors are ...
Yuichi Takano, Naoki Tamai, Jun Noda, Tetsushi Azami, Fumitaka Niiya, Tatsuya Yamagami, Akihiro Nakamura, Genshu Tate, Takafumi Ogawa, Masatsugu Nagahama   +9 more
wiley   +1 more source