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Intralesional Antigen Immunotherapy in the Treatment of Periungual Warts
Journal of Cutaneous Medicine and Surgery, 2021Background Intralesional immunotherapy using different types of antigens is considered an effective and safe treatment option for different types of warts. However, there are few studies that illustrate the use of these antigens in the treatment of periungual warts as a distinct type of warts.
Rania Alakad +2 more
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Intralesional immunotherapy as a strategy to treat melanoma
Expert Opinion on Biological Therapy, 2016Intralesional immunotherapy supplements systemic treatments and often achieves higher remission rates as compared to systemic therapy. Its indication is metastatic melanoma with limited tumor burden, particularly in loco-regional metastasis and distant soft tissue metastasis.This review describes intralesional immunotherapy with talimogene ...
Claus Garbe
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Intralesional and systemic immunotherapy for metastatic melanoma
Expert Opinion on Biological Therapy, 2016Immunotherapy has revolutionized the treatment of metastatic melanoma and dramatically improved patient outcomes. Ipilimumab, an inhibitor of cytotoxic T-lymphocyte antigen-4 (CTLA-4), was the first immunotherapeutic agent to demonstrate improved survival in advanced melanoma.
Nikhil Khushalani, Carrie Luu
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Intralesional immunotherapy for melanoma
Journal of Surgical Oncology, 2013Intralesional immunotherapy of melanoma has two complementary aims. One is to cause regression of the injected metastasis. The other is to incite or modulate systemic immune responses in such a way that non‐injected metastases will also undergo regression.
Peter, Hersey, Stuart, Gallagher
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Intralesional Immunotherapy of Melanoma with BCG
Medical Clinics of North America, 1976Treatment of recurrent cutaneous melanoma nodules with BCG is an effective and relatively nonmorbid method for eliminating these tumor nodules. Injected nodules can be made to disappear about 90 per cent of the time and in about 20 per cent of patients non-injected nodules in the same drainage area may also regress.
S A, Rosenberg, H J, Rapp
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Intralesional antigen immunotherapy for the treatment of plane warts: A comparative study
Dermatologic Therapy, 2020Intralesional immunotherapy by different antigens has shown promising efficacy and safety in the treatment of warts. However, the use of these antigens for the treatment of plane warts has been investigated in two studies only. To evaluate the efficacy and safety of three antigens; Measles Mumps, Rubella vaccine (MMR), Candida antigen, and purified ...
Rania Alakad +2 more
exaly +3 more sources
Intralesional Cancer Immunotherapies
Hematology/Oncology Clinics of North America, 2019Melanoma and other solid cancers with low or absent T-cell inflammation respond poorly to immune checkpoint inhibitors. Tumor infiltration with T cells that are directed against tumor antigens requires the induction of an innate immune response leading to production of type I interferons and maturation and activation of dendritic cells that can cross ...
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Intralesional immunotherapy compared to cryotherapy in the treatment of warts
International Journal of Dermatology, 2017AbstractBackgroundWarts are the most common clinical manifestation of the human papilloma‐virus infection in the skin and mucous membranes. In spite of the various therapeutic modalities for nongenital skin warts, there is still no single method to be used as an approved treatment.
Fahime, Khozeimeh +6 more
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Intralesional and Topical Chemotherapy and Immunotherapy
Veterinary Clinics of North America: Equine Practice, 1998Surgery is the mainstay of treatment for equine tumors. Conservative treatment approaches which preserve function and appearance are increasingly used in clinical practice. This article covers the principles and applications of two conservative treatment modalities including local chemotherapy and immunotherapy.
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Immunotherapy with an intralesionally administered synthetic cord factor analogue
International Journal of Cancer, 1978AbstractInjection of emulsified 6,6′‐di‐O‐2‐tetradecyl‐3‐hydroxyoctadecanoyl‐α,α trehalose designated C76, a synthetic analogue of the mycobacterial glycolipid trehalose‐6,6′‐dimycolate (TDM), into transplants of an established, syngeneic murine fibrosarcoma induced complete regression of tumor in a number of animals.
Yarkoni, E +3 more
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