Results 81 to 90 of about 149,549 (197)

Gardiquimod Nanoemulsion Targets Cutaneous Leishmaniasis Lesions Reducing Systemic Toxicity and Parasite Burden

Advanced Healthcare Materials, Volume 15, Issue 30, 14 August 2026.
Nanoemulsion delivery of a TLR7 agonist enhances safety and promotes colocalization with Leishmania‐infected macrophages in skin lesions, enabling a ∼2‐log reduction in parasite burden. However, tissue‐level constraints and TLR‐driven regulatory feedback generate a mixed immune response that limits complete parasite clearance.
Carmen Palomino‐Cano, M. Carmen Mera‐Delgado, Esther Moreno, Esther Larrea, Lecnia Aguirre, Jonathan Miguel Zanatta, Sónia Barros‐Carvalho, Iola F. Duarte, Ricardo Silvestre, Juan M. Irache, Javier Carrión, Socorro Espuelas   +11 more
wiley   +1 more source

A randomized double blind controlled study comparing the efficacy of intralesional MMR vaccine with normal saline in the treatment of cutaneous warts

Indian Dermatology Online Journal, 2018
Background: Recently, with better understanding of the immunology of warts, immunotherapeutic approaches have emerged as an effective treatment option for the management of cutaneous warts.
Chesta Agrawal, Kapil Vyas, Asit Mittal, Ashok K Khare, Lalit K Gupta   +4 more
doaj   +1 more source

Response to a combination therapy of cemiplimab and cetuximab in cutaneous squamous cell carcinoma – a case report

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Katja Schabet, Louisa Schielein, Alexander Enk, Jessica C. Hassel   +3 more
wiley   +1 more source

Candida Albicans versus Candida Tropicalis Antigens in Treatment of Recalcitrant Wart [PDF]

Zagazig University Medical Journal
Background: Recalcitrant warts often require immune-based therapies, with Candida albicans antigen being the most used modality. Little is known about the clinical performance of Candida tropicalis as an alternative antigen despite biological ...
Amin Amer, Ayman Marei, Fatma Elzahraa Elshamy, Hala Morsi   +3 more
doaj   +1 more source

Evaluation of Intralesional Triamcinolone Acetonide and Platelet‐Rich Plasma Therapy in Patients With Mild Patch‐Type Alopecia Areata

Journal of Cosmetic Dermatology, Volume 25, Issue 8, August 2026.
ABSTRACT Introduction Alopecia areata is a long‐term autoimmune disease that causes hair loss in approximately 2% of people but does not result in permanent scarring. Intralesional corticosteroid treatment provides effective results; however, long‐term use may lead to skin atrophy and telangiectasia.
Ramazan Ülker, İlknur Yorğun Özdemir, Hatice Uce Özkol   +2 more
wiley   +1 more source

Measles, mumps and rubella vaccine as an intralesional immunotherapy in treatment of warts [PDF]

, 2016
Background: To observe the efficacy and safety of intralesional Measles Mumps and Rubella (MMR) vaccine in the treatment of warts.Methods: 50 patients with single or multiple warts more than 06 months duration in all age groups were included in the study.
Patel, Dhara, Shah, Aarti N., Ravishankar, Vaaruni   +2 more
core   +1 more source

Updates on intratumoral therapies in melanoma

Cancer, Volume 132, Issue 13, 1 July 2026.
Abstract Intratumoral therapies provide an opportunity for novel strategies in the management of advanced melanoma. These approaches deliver concentrated doses of therapeutic immune agents directly into individual tumor(s), achieving local tumor control and induction of systemic antitumor immune responses while minimizing the risk of immune‐related ...
Vincent T. Ma, Alyssa K. Steimle, Janmesh D. Patel, Caroline Burkey, Justin C. Moser, Asad Javed, Hibba tul Rehman, Mustafa Ege Seker, Alexander Birbrair, Orhan S. Ozkan, Mark R. Albertini, Yana G. Najjar, Rajan P. Kulkarni   +12 more
wiley   +1 more source

Intralesional immunotherapy for difficult to treat warts with Mycobacterium w vaccine.

J Cutan Aesthet Surg, 2014
Immunotherapy is an evolving therapeutic modality for the treatment of warts. We conducted a study to assess the efficacy and safety of intralesional Mycobacterium w vaccine for the treatment of warts at sites that were difficult to treat.Thirty patients with at least one wart present on either the plantar surface of their feet, palms, volar aspect of ...
Garg S, Baveja S.
europepmc   +3 more sources

Systemic Immunosuppression to Reduce Surgical Intervention in ANCA‐Negative Subglottic Stenosis

The Laryngoscope, Volume 136, Issue 7, Page 3103-3110, July 2026.
Idiopathic subglottic stenosis (iSGS) typically follows an indolent course managed with surgical dilatation, though a subset demonstrates aggressive, recurrent disease. In this retrospective cohort study, systemic immunosuppression significantly prolonged inter‐dilation intervals in both granulomatosis with polyangiitis‐associated SGS and an “atypical”
Guy Benshetrit, Stephen McAdoo, Romana Kuchai, Charles Pusey, Guri Sandhu, Chadwan Al‐Yaghchi   +5 more
wiley   +1 more source

Intralesional Talimogene Laherparepvec Immunotherapy for Melanoma: A Case Study

Cureus
Melanoma, characterized by its aggressive nature and tendency for metastasis, presents a significant challenge in clinical management. While surgical excision remains the gold standard for localized disease, therapeutic advancements for advanced stages are crucial.
Ghebrehiwet, Merhawit, Pavlis, Janelle, Gomez-Meade, Carlos   +2 more
openaire   +2 more sources