Results 161 to 170 of about 90,335 (298)

Redrawing the Mannich‐Type Reaction through Carbonyl Umpolung Reactivity

Advanced Synthesis &Catalysis, EarlyView.
GA: Herein, a conceptually novel one‐pot multicomponent strategy is reported for the streamlined construction of five‐membered imidazolidines from 1,2‐diaza‐1,3‐dienes (onefold), amines (twofold), and formaldehyde (twofold). This redesigned Mannich‐type reaction that exploits a carbene‐like activity of 1,2‐diaza‐1,3‐dienes (realized by “umpolung ...
Vittorio Ciccone, Sara Caselli, Giacomo Mari, Fabio Mantellini, Gianfranco Favi   +4 more
wiley   +1 more source

Evidence for Intramolecular Antiparallel Beta-Sheet Structure in Alpha-Synuclein Fibrils from a Combination of Two-Dimensional Infrared Spectroscopy and Atomic Force Microscopy

, 2017
Steven J. Roeters, Aditya Iyer, Galja Pletikapić, Vladimir Kogan, Vinod Subramaniam, Sander Woutersen   +5 more
openalex   +1 more source

Visible‐Light‐Promoted Dearomatization for The Construction of Imidazole Scaffolds

Advanced Synthesis &Catalysis, EarlyView.
Lighting up flat aromatics: a visible‐light photocatalytic dearomative acylation of imidazo[1,2‐a]pyridines using α‐keto acids as sustainable acyl radical precursors is reported, leading to dual fluorescent imidazoles. Dearomatization is a powerful strategy for constructing complex carbocycles and heterocycles, though it typically relies on harsh ...
Silvia Roscales, Aurelio G. Csáky
wiley   +1 more source

Fe‐Photocatalyzed Decarboxylative Giese‐Type Reaction of α‐N, O or S Carboxylic Acids: Insight into the Mechanism of the Radical Formation

Advanced Synthesis &Catalysis, EarlyView.
Electron‐deficient alkenes can be functionalized with α‐amino, α‐alkoxy and α‐alkylthio radicals formed by Fe‐photocatalyzed decarboxylation of the corresponding carboxylic acids. The reactions proceed under smooth ligandless conditions with inexpensive base and in the absence of oxidant. A mechanistic computational TD‐DFT study supports the occurrence
Fernando Pérez‐Maseda, María Martín, Jorge Labrador‐Santiago, Inés Corral, Diego J. Cárdenas   +4 more
wiley   +1 more source

Semi-Interpenetrating Polymer Networks Based on N-isopropylacrylamide and 2-acrylamido-2-methylpropane Sulfonic Acid for Intramolecular Force-Compensated Sensors

, 2020
Simon Binder, Stefan Zschoche, Brigitte Voit, Gerald Gerlach   +3 more
openalex   +1 more source

Recent Advances in Ene Reactions with Carbon Enophiles

Advanced Synthesis &Catalysis, EarlyView.
Recent advances in the classical intra‐ and intermolecular ene nexus with carbon enophiles (alkenes, alkynes, arynes, and allenes) show a considerable increase in structural complexity and an enormous potential for functional applications in polymer science.
Thomas J. J. Müller
wiley   +1 more source

Cu(I)‐Catalyzed Interrupted Cycloaddition Between Azides, Ag(I)‐Acetylides, and Diorganoyl Dichalcogenides

Advanced Synthesis &Catalysis, EarlyView.
Unleashing the power of Ag(I)‐acetylides with LiCl/dimethyl sulfoxide (DMSO). The LiCl/DMSO mixture have an unexplored ability to dramatically increase the solubility of Ag(I)‐acetylides regardless of their molecular structure, which is explored to achieve high chemoselectivity in the Cu(I)‐catalyzed interrupted cycloaddition between organic azides, Ag(
Diego Seckler, Eduardo Q. da Luz, Gabriel L. Silvério, Francielli Sousa Santana, Gul Badshah, Wystan K. Teixeira, Caroline R. Montes D’Oca, Ricardo S. Schwab, Daniel S. Rampon   +8 more
wiley   +1 more source

Transient non-local interactions dominate the dynamics of measles virus N_TAIL. [PDF]

Commun Chem
Otteson L, Nagy G, Kunkel J, Kodis G, Bock LV, Bignon C, Longhi S, Zheng W, Grubmüller H, Vaiana AC, Vaiana SM.   +10 more
europepmc   +1 more source

Heterogeneous Copper‐Catalyzed 1,4‐Conjugate Additions of Grignard Reagents to Cyclic and Linear Enones

Advanced Synthesis &Catalysis, EarlyView.
The 1,4‐conjugate addition of Grignard reagents to various cyclic and linear enones using a heterogeneous catalyst is reported. Recyclable copper nanoparticles immobilized on polysaccharide support (e.g., cellulose, chitosan) enable high chemo‐ and regioselectivity.
Luca Deiana, Abdolrahim A. Rafi, Haibo Wu, Shobhan Mondal, Jan‐E. Bäckvall, Armando Córdova   +5 more
wiley   +1 more source

Elucidation of the Molecular Interaction Network Underlying Full-Length FUS Conformational Transitions and Its Phase Separation Using Atomistic Simulations. [PDF]

J Phys Chem B
Weng SL, Mohanty P, Mittal J.
europepmc   +1 more source