Results 41 to 50 of about 324,399 (368)
Dual-acting therapeutic proteins for intraocular use
, 2021 Antibody-based medicines that target vascular endothelial growth factor (VEGF) are administered by intravitreal injection (IVI) to treat chronic neovascular retinal diseases.
Ibeanu, N. +6 more
core +1 more source
Frontiers in OncologyPurposeTo evaluate the prognostic significance of BRCA1-associated protein 1 (BAP1) nuclear expression in enucleated eyes with uveal melanoma (UM), and to compare its predictive value with classical clinicopathological factors in a large Spanish cohort ...
Patricia Valencia Nieto +11 more
doaj +1 more source
Rare foreign bodies encountered in ophthalmic practice
Journal of Clinical Ophthalmology and Research, 2021 Ocular trauma and retained foreign bodies in the eye form a common occurrence in ophthalmic practice. Mild trauma may often be overlooked and patients, quite often, present late with serious complications.
Sudha Menon +2 more
doaj +1 more source
International Journal of Ophthalmology, 2017 Intraocular lymphoma (IOL) is a rare lymphocytic malignancy which contains two main distinct forms. Primary intraocular lymphoma (PIOL) is mainly a sub-type of primary central nervous system lymphoma (PCNSL). Alternatively, IOL can originate from outside the central nervous system (CNS) by metastasizing to the eye.
Li-Juan Tang, Chang-Lin Gu, Ping Zhang
openaire +3 more sources
Advanced Healthcare Materials, EarlyView.A thermo‐responsive poly(2‐oxazoline)‐based injectable formulation is developed to modulate intraocular pressure (IOP) in both normal and hypotonic eyes. By adjusting the PEG content, the aggregation behavior is finely tuned, enabling IOP elevation without long‐term deposition.
Yuji Tanaka +2 more
wiley +1 more source
In-vivo sclera thickness measurements in experimental myopia of guinea pigs
BMC OphthalmologyThe sclera is the target organ of axial elongation during myopia onset and progression. Visualizing the sclera in-vivo is important for monitoring the dynamic changes of the sclera remodeling in experimental myopia.
Ruiheng Zhang +8 more
doaj +1 more source
First-in-human study of the safety and viability of intraocular robotic surgery
Nature Biomedical Engineering, 2018 Microsurgery of the retina would be dramatically improved by instruments that offer supra-human precision. Here, we report the results of a first-in-human study of remotely controlled robot-assisted retinal surgery performed through a telemanipulation ...
T. L. Edwards +9 more
semanticscholar +1 more source
Aptamer‐Based Delivery Systems for VEGF and NGF Modulation in Ocular Therapies
Advanced Healthcare Materials, EarlyView.Aptamer‐based delivery systems targeting NGF and VEGF hold significant potential for precise and sustained treatment of complex diseases affecting both the anterior and posterior segments of the eye. This review critically summarizes current strategies for NGF and VEGF delivery as well as VEGF sequestration, providing a clinical perspective on how ...
Nadine Best +5 more
wiley +1 more source
BMC OphthalmologyObjective To investigate the recovery of binocular stereopsis recovery and its influencing factors in children with intermittent exotropia after successful correction of eye position. Methods Prospective clinical study.
Guohong Zhao +4 more
doaj +1 more source
Long‐Term Hydrophilic, Anti‐Clotting, and Anti‐Fibrotic Dynamic Covalent Silicone‐Based Biomaterials
Advanced Healthcare Materials, EarlyView.Dynamic covalent crosslinking of a Schiff‐base silicone elastomer with hydrazide‐functionalized polymers is demonstrated to improve the long‐term hydrophilicity as well as the anti‐fouling and anti‐clotting properties of PDMS implants. The hydrazone‐functionalized material prevents hydrophobic recovery, resists clotting, and significantly reduces ...
Norma A. Garza Flores +12 more
wiley +1 more source