Results 51 to 60 of about 772,493 (250)

Changing paradigms of anti-VEGF in the Indian scenario

Indian Journal of Ophthalmology, 2014
Anti-vascular endothelial growth factors (VEGF) agents have revolutionized the treatment of retinal diseases. Use of anti-VEGF agents in the Indian Scenario present some unique challenges considering the absence of compounding pharmacies, poor penetrance
P Mahesh Shanmugam
doaj   +1 more source

Intraocular light scatter as modeled through a stratified medium [PDF]

, 2001
Intraocular light scatter is modeled through a stratified medium. It is shown that the eye lens possesses properties of an interference filter. In conditions that may mimic opacification, as found with cataract formation, such a filter may have stop ...
Pierscionek, Barbara, Dolgobrodov, Sergey G., Green, Roger   +2 more
core   +1 more source

An Aggregation‐Induced Polymerization Poly(Disulfide)‐Drug Nanoplatform for Autoimmune Uveitis Therapy via Inhibiting the cGAS‐STING Pathway

Advanced Science, EarlyView.
A cationic poly(disulfide)‐drug nanoplatform (LA/DexP) was developed to treat experimental autoimmune uveitis (EAU). With potent blood‐retinal barrier penetrability, LA/DexP releases DSP in response to high ROS and scavenges cfDNA to inhibit the cGAS‐STING signaling pathway.
Yuelan Wu, Wenbo Geng, Qinjin Dai, Wanyun Zhang, Yuxian Lai, Pei Zhang, Chunjiang Zhou, Yinuo Wang, Qingfeng Cao, Xiang Luo, Yujie Lai, Changwei Huang, Peizeng Yang   +12 more
wiley   +1 more source

Performance Estimation and Ex Vivo Validation of Untethered Magnetic Robots in Soft Tissue

Advanced Science, EarlyView.
This study presents an empirical model that quantitatively predicts the step‐out frequency of screw‐type untethered magnetic robots (UMRs) in soft viscoelastic environments, including ex vivo brain tissue. By integrating key parameters into a dimensionless framework, the model enables estimation of robot performance across a range of biological ...
Leendert‐Jan W. Ligtenberg, Thijs J. van der Burg, Stijn Y. Kolkman, Santiago Saavedra Castano, David Fernandez Rivas, Anke Klingner, Roger M. L. M. Lomme, Lucas S. Joziasse, Dorothee Wasserberg, H. Remco Liefers, Doron Ben Ami, Udi Sadeh, Oded Shoseyov, Giulio Dagnino, Pascal Jonkheijm, Jurgen J. Fütterer, Stefano Stramigioli, J. Frank W. Nijsen, Michiel C. Warlé, Islam S. M. Khalil   +19 more
wiley   +1 more source

Evaluating Exaggerated, Prolonged, or Delayed Postoperative Intraocular Inflammation

, 2010
To provide a diagnostic approach for the evaluation of patients with exaggerated, prolonged, or delayed postoperative intraocular inflammation. Perspective. Selected articles on normal and abnormal postoperative intraocular inflammation were reviewed and
J. Fernando Arevalo, Harry W. Flynn, Cunningham, Emmett T, Flynn, Harry W, Emmett T. Cunningham, Doshi, Rishi R, Rishi R. Doshi, Arevalo, J. Fernando   +7 more
core   +1 more source

Biocompatibility of Intraocular Lenses [PDF]

, 2017
The performance of an intraocular lens is determined by several factors such as the surgical technique, surgical complications, intraocular lens biomaterial and design, and host reaction to the lens.
Özyol, Pelin, Fatih Karel, Karel, Fatih, Pelin Özyol, Erhan Özyol, Özyol, Erhan   +5 more
core   +1 more source

Comparison of clinical characteristics between cases with and without intraocular inflammation after brolucizumab injection.

, 2021
Comparison of clinical characteristics between cases with and without intraocular inflammation after brolucizumab injection.
Hidetaka Matsumoto (145974), Ryo Mukai (6204680), Hideo Akiyama (168229)   +2 more
core   +1 more source

A Site‐Aware Representation Learning Framework For Unified Molecular Interaction Modeling and Generative Design

Advanced Science, EarlyView.
MolDBG is a site‐aware, sequence‐only framework that unifies drug‐target affinity prediction, binding‐site identification, and affinity‐conditioned molecular generation for structured proteins. Guided by multi‐task binding‐site supervision, it aligns interaction‐critical residues before learning drug‐target representations and simultaneously infers ...
Gang Luo, Qianqian Zhang, Chenhao Wang, Zhiheng Yi, Alex Jinpeng Wang, Jing Tang, Min Li   +6 more
wiley   +1 more source

From Sensing Mechanisms to System Co‐Design: Graphene‐Based Sensors and Readout Circuits

Advanced Science, EarlyView.
This review establishes a unified PS–EQ–RF framework linking graphene sensing mechanisms, native electrical outputs, and output‐specific readout circuits. Voltage‐, current‐, resistance‐, and capacitance‐type sensing systems are systematically classified to guide architecture selection, low‐noise design, system co‐design, and practical integration ...
Jinduo Zhang, Meng Chen, Guanchen Li, Ruifeng Liu, Yingxin Wang, Ziran Zhao   +5 more
wiley   +1 more source

Brolucizumab: Evaluation of Compassionate Use of a Complex Anti-VEGF Therapy

Clinical Ophthalmology, 2021
Julianna E Murray, Aaron S Gold, Azeema Latiff, Timothy G Murray Private Practice, Miami Ocular Oncology & Retina, Miami, FL, USACorrespondence: Timothy G MurrayMiami Ocular Oncology & Retina, 6705 Red Road Suite 412, Miami, FL, 33143, USAEmail tmurray ...
Murray JE, Gold AS, Latiff A, Murray TG
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