Results 61 to 70 of about 772,493 (250)

Potential of Nanoparticle‐Based Phototherapies for Future Treatment of Uveal Melanoma

Advanced Science, EarlyView.
This review evaluates nanoparticle‐based phototherapies for uveal melanoma, highlighting emerging strategies to enhance tumor targeting, light delivery, and treatment precision. Preclinical data indicate improved efficacy and reduced toxicity, supporting their potential to enhance localized treatment and future translational advances. (Generated by the
Emilie Lambert, Christophe Nguyen, Sean Edward Dunn, Magali Gary‐Bobo, Jérôme Lacombe, Justin Moser, Frédéric Zenhausern, Jean‐Olivier Durand, Frédérique Cunin   +8 more
wiley   +1 more source

Aflibercept-Related Sterile Intraocular Inflammation Outcomes

, 2019
© 2019 American Academy of Ophthalmology Purpose: A recent increase in sterile intraocular inflammation after aflibercept (EYLEA; Regeneron Pharmaceuticals, Inc, Tarrytown, NY) injection was reported to the American Society of Retina Specialists ...
Jonathan P. Greenberg, Philip J. Ferrone, Ferrone, P. J., Butler, J., Peter Belin, Mueller, C., Geoffrey G. Emerson, Feiler, D., Tye, A., Daniel Feiler, Belin, P., Friedlander, S. M., Andrew Tye, Greenberg, J. P., Christian Mueller, Steven M. Friedlander, Emerson, G. G., John Butler   +17 more
core   +1 more source

Th17 Activation and Th17/Treg Imbalance in Prolonged Anterior Intraocular Inflammation after Ocular Alkali Burn

, 2022
Ocular alkali burn (OAB) is a sight-threatening disease with refractory ocular inflammation causing various blinding complications. Th17 lymphocytes account for the pathogeneses of the autoimmune disease and chronic inflammation, but their role in ...
Lin, Xiaofeng, Yao Yang, Duan, Fang, Lou, Bingsheng, Xiaobing Qian, Bingsheng Lou, Qian, Xiaobing, Huang, Yanqiao, Xinqi Ma, Ma, Xinqi, Xiaofeng Lin, Yanqiao Huang, Fang Duan, Yang, Yao, Miner Yuan, Yuan, Miner   +15 more
core   +1 more source

Self‐Propelled HPB@Lip@AB Nanomotors Ameliorate Dry Eye Disease

Advanced Science, EarlyView.
A self‐propelled HPB@Lip@AB nanomotor system is developed for dry eye disease (DED) therapy, facilitating rapid penetration across ocular surface barriers while integrating hydrogen therapy with multi‐enzyme‐like antioxidant activity. The nanoplatform restores mitochondrial function, suppresses oxidative stress, inflammation, and apoptosis, and ...
Jing Li, Xi Wan, Xinru Su, Zechuan Li, Yue Wang, Ying Wang, Ruofei Li, Huangzhao Wei, Jianbin Zhang, Shuai Wang   +9 more
wiley   +1 more source

Comparative results of use and switching of anti-TNF-alpha agents in adult Behçet’s uveitis

Indian Journal of Ophthalmology
Purpose: This study was planned to compare the clinical results and optical coherence tomography (OCT) data of patients who underwent adalimumab (ADA), infliximab (IFX) and switched protocols between these two methods in cases of Behçet’s associated ...
Selma Mesen, Muhammet D Ozer, Muhammed Batur   +2 more
doaj   +1 more source

Antibiotics Treatment in Intraocular Infection

, 2020
Generally, broad-spectrum antibiotics are chosen to be the initial treatment to administer at the appropriate site of infection as soon as a diagnosis is made to prevent from any delay in treatment.
Lin, Shao-Ting
core  

Intraocular inflammation following endotamponade with high-density silicone oil. [PDF]

, 2004
Contains fulltext : 57861.pdf (Publisher’s version ) (Open Access)BACKGROUND: The use of a mixture of silicone oil and partially fluorinated alkanes (high-density silicone oil) has recently been suggested as intraocular tamponade in ...
Klevering, B.J., Tilanus, M.A.D., Theelen, T.   +2 more
core   +1 more source

CRISPR and Gene Augmentation Rescue Trabecular Meshwork Dysfunction in iPSC Models of Lowe Syndrome

Advanced Science, EarlyView.
By modeling Lowe syndrome using patient‐derived iPSCs, this study establishes a human disease model that faithfully recapitulates OCRL deficiency‐associated ciliary and cytoskeletal defects. The model enables evaluation of both mutation‐agnostic DNA augmentation and CRISPR‐mediated mutation correction strategies, both of which restore OCRL function and
Siyu Chen, Zhiquan Liu, Wenmin Wang, Qing Wang, Tia J. Kowal, Fan Zhang, Grzegorz Walkiewicz, Faruk Hossen, Herbert M. Lachman, Jinqiong Zhou, Yiting Wang, Yang Sun   +11 more
wiley   +1 more source

In Situ Photo‑Crosslinked Functional Bilayer Hydrogel Modulates Local Microenvironment and Remyelination After Optic Nerve Injury

Advanced Science, EarlyView.
A blue‐light‐crosslinked bilayer hydrogel was developed for local optic nerve repair. The adhesive GM‐Odex outer layer seals and anchors the lesion, while the non‐adhesive GM‐imid inner layer releases MPDA‐Cle without obstructing CSF flow. This system modulates oxidative and inflammatory microenvironments, supports oligodendrocyte differentiation and ...
Tonghe Pan, Yate Huang, Junhao Zhang, Shudong Tian, Zhixing Li, Xuanwen Li, Yanchen Zhang, Dongmei Wang, Sihao Ye, Ming Jin, Neng Ling, Wentao Yan, Kaihui Nan, Wencan Wu   +13 more
wiley   +1 more source

Intracameral dexamethasone injection in the treatment of cataract surgery induced inflammation: design, development, and place in therapy

Clinical Ophthalmology, 2018
Tirth J Shah,1 Mandi D Conway,1,2 Gholam A Peyman1,2 1Department of Ophthalmology, University of Arizona College of Medicine, Phoenix, Arizona, USA; 2Department of Ophthalmology, Tulane University College of Medicine, New Orleans, Louisiana, USA ...
Shah TJ, Conway MD, Peyman GA
doaj