Results 81 to 90 of about 1,361,126 (321)

Keratoprostheses for corneal blindness: a review of contemporary devices [PDF]

, 2015
According to the World Health Organization, globally 4.9 million are blind due to corneal pathology. Corneal transplantation is successful and curative of the blindness for a majority of these cases. However, it is less successful in a number of diseases
Avadhanam, Venkata, Liu, Christopher, Smith, Helen   +2 more
core   +1 more source

Dual‐Targeting Cuproptosis and Mitophagy via a Flavopiridol‐Copper Nanoplatform Potentiates Immunotherapy Against Uveal Melanoma

Advanced Science, EarlyView.
This study develops a GSH‐responsive nanoplatform, NP@Fla‐Cu, to co‐activate cuproptosis and excessive mitophagy in uveal melanoma. The nanoplatform enhances tumor‐specific copper delivery, depletes antioxidant defenses, and remodels the tumor immune microenvironment.
Hong Ren, Zhihong Deng, Sheng Lu, Jing Zhang, Wenbin Liu, Jia Tan   +5 more
wiley   +1 more source

Tibial Periosteum For The Surgical Perforation [PDF]

, 2016
Purpose: Report a successful case of scleral perforation repair, refractive to treatment with bank-scleral graft, using pretibial periosteum graft patch.
Mateo A, Rodrigo MJ, , Abecia E, Idoipe M, Hualde A, Satue M   +5 more
core   +1 more source

GHRHR Deficiency Enhances Retinal Ganglion Cell Survival and Visual Functions in Experimental Glaucoma by Inhibiting Ferroptosis

Advanced Science, EarlyView.
Glaucoma, a major cause of blindness, involves retinal ganglion cell (RGC) degeneration. This study shows growth hormone‐releasing hormone receptor (GHRHR) deficiency preserves RGC survival and restores vision, unlike activation which only aids survival.
Yan Tong, Ming Ho Yam, Jiaxin Zhang, Lin Du, Linbin Zhou, Yolanda Wong Ying Yip, Bo Man Ho, Hemlata Bisnauthsing, Jiahui Li, Ivan Kong, Shushu Xu, Changzhen Fu, Karl K.H. So, Joaquim S.L. Vong, Ling‐Ping Cen, Ming‐Ming Yang, Khazeema Yousaf, Mai Har Sham, Sun On Chan, Poemen P. Chan, Chi Pui Pang, Clement C. Tham, Jing Na He, Jian Li, Wai Kit Chu   +24 more
wiley   +1 more source

Retinal Detachment After Endophthalmitis: Risk Factors and Outcomes

Clinical Ophthalmology, 2021
Tiantian Wang,1,2 Omar Moinuddin,1 Rebhi Abuzaitoun,1 Min Hwang,1 Cagri Besirli,1 Thomas J Wubben,1 David N Zacks1 1Department of Ophthalmology and Visual Sciences, University of Michigan W.K.
Wang T, Moinuddin O, Abuzaitoun R, Hwang M, Besirli C, Wubben TJ, Zacks DN   +6 more
doaj  

Non-infectious Intraocular Inflammation Following Intravitreal Anti-Vascular Endothelial Growth Factor Injection

Türk Oftalmoloji Dergisi, 2021
Objectives:To evaluate the functional and anatomical results of patients with non-infectious intraocular inflammation (IOI) following intravitreal anti-vascular endothelial growth factor (anti-VEGF) injection for the treatment of neovascular age-related ...
Mahmut Kaya, Ferit Hakan Öner, Betül Akbulut Yağcı, Ferdane Ataş, Taylan Öztürk   +4 more
doaj   +1 more source

Decoding Undesirable Inflammatory Responses of Nucleic Acid‐Delivering Lipid Nanoparticles

Advanced Science, EarlyView.
Lipid nanoparticles (LNPs) enable efficient nucleic acid delivery, but their immunogenicity is a double‐edged sword. This review explores LNP‐driven innate and adaptive immunity, covering lipid components, endosomal escape, and nucleic acid sensing.
Ruimin Hu, Yin Dou, Chenwen Li, Yuying Mu, Huiying Ouyang, Wenhao Shen, Jianxiang Zhang   +6 more
wiley   +1 more source

Intracameral dexamethasone injection in the treatment of cataract surgery induced inflammation: design, development, and place in therapy

Clinical Ophthalmology, 2018
Tirth J Shah,1 Mandi D Conway,1,2 Gholam A Peyman1,2 1Department of Ophthalmology, University of Arizona College of Medicine, Phoenix, Arizona, USA; 2Department of Ophthalmology, Tulane University College of Medicine, New Orleans, Louisiana, USA ...
Shah TJ, Conway MD, Peyman GA
doaj  

The Impact of Vitreoretinal Surgery in Patients with Uveitis: Current Strategies and Emerging Perspectives

Diagnostics
Uveitis constitutes a heterogeneous group of intraocular inflammatory pathologies, including both infectious and non-infectious aetiologies, often leading to substantial morbidity and permanent loss of vision in up to 20% of the affected cases.
Dimitrios Kalogeropoulos, Sofia Androudi, Marta Latasiewicz, Youssef Helmy, Ambreen Kalhoro Tunio, Markus Groppe, Mandeep Bindra, Mohamed Elnaggar, Georgios Vartholomatos, Farid Afshar, Chris Kalogeropoulos   +10 more
doaj   +1 more source

Intraocular inflammation after Ultrasound Cyclo Plasty for the treatment of glaucoma.

International Journal of Ophthalmology, 2019
This is a prospective interventional clinical study evaluating intraocular inflammation developed after Ultrasound Cyclo Plasty (UCP) for the treatment of glaucoma.
M. Pellegrini, Stefano Sebastiani, Giuseppe Giannaccare, E. Campos   +3 more
semanticscholar   +1 more source