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Hyperthermic Intraperitoneal Chemotherapy: A Critical Review [PDF]
With increasing awareness amongst physicians and improved radiological imaging techniques, the peritoneal cavity is increasingly recognized as an important metastatic site in various malignancies. Prognosis of these patients is usually poor as traditional treatment including surgical resection or systemic treatment is relatively ineffective ...
Wim Ceelen+2 more
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Hyperthermic Intraperitoneal Chemotherapy in Ovarian Cancer [PDF]
(Abstracted from N Engl J Med 2018;378:230–240) The majority of patients with ovarian cancer (OC) receive an initial diagnosis of advanced disease that has spread from the ovaries to the peritoneal surface. The most effective treatment for patients with advanced disease is cytoreductive surgery followed by systemic chemotherapy.
Ceresoli, M, Frigerio, L, Ansaloni, L
semanticscholar +20 more sources
Intraperitoneal Chemotherapy of Ovarian Cancer [PDF]
Ovarian cancer is the leading cause of death among cancers of the female reproductive tract. Most women present with regionally advanced intraperitoneal disease with superficial spread of tumor along the peritoneal surfaces. Distant metastasis rarely occurs until late in the disease process; however, long-term survival of patients with advanced ...
Robert J Morgan, Thomas Lowe
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Peritoneal spread of tumors is a major problem in cancer management. Patients develop a marked deterioration in quality of life and shortened survival. This is in part due to bowel obstructions, marked ascites, and overall increase debilitation. Standard medical management has shown to be inadequate for the treatment of these problems.
Sarah J. McPartland+3 more
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Critical evaluation of the benefits of intraperitoneal (IP) chemotherapy.Critical review of the literature in support of the administration of chemotherapy via the IP route.The 3 largest randomized phase III trials conducted by the Gynecologic Oncology Group and published over a 10-year period clearly demonstrated a 19% to 25% reduction in risk of ...
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Ovarialkarzinom: Chemotherapie intraperitoneal? [PDF]
Die intraperitoneale Applikation der Chemotherapie bei fortgeschrittenem Ovarialkarzinom wird nicht routinemasig eingesetzt. Anhand gepoolter Daten der GOG (Gynecologic Oncology Group) wurde der Langzeiterfolg uberpruft.
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Anesthetic implications in hyperthermic intraperitoneal chemotherapy
Patients with peritoneal carcinomatosis were considered incurable with dismal survival rates till hyperthermic intraperitoneal chemotherapy after optimal cytoreductive surgery evolved. Perioperative management for these procedures is complex and involves an optimal cytoreductive surgery followed by hyperthermic intraperitoneal chemotherapy.
Sachidanand Jee Bharti+5 more
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Effect of hyperthermic intraperitoneal chemotherapy on thrombin generation and fibrinolysis. [PDF]
Lundbech M+4 more
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Intraperitoneal chemotherapy is now back for ovarian cancer. [PDF]
Fujiwara K, Nagao S, Tan D, Hasegawa K.
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