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Hyperthermic Intraperitoneal Chemotherapy: A Critical Review [PDF]

open access: yesCancers, 2021
With increasing awareness amongst physicians and improved radiological imaging techniques, the peritoneal cavity is increasingly recognized as an important metastatic site in various malignancies. Prognosis of these patients is usually poor as traditional treatment including surgical resection or systemic treatment is relatively ineffective ...
Wim Ceelen   +2 more
openaire   +6 more sources

Morbidity and Mortality Rates Following Cytoreductive Surgery Combined With Hyperthermic Intraperitoneal Chemotherapy Compared With Other High-Risk Surgical Oncology Procedures [PDF]

open access: goldJAMA Network Open, 2019
Key Points Question What are the morbidity and mortality of cytoreductive surgery combined with hyperthermic intraperitoneal chemotherapy (CRS/HIPEC) compared with other major oncologic surgical procedures?
Jason M. Foster   +7 more
openalex   +2 more sources

Hyperthermic intraperitoneal chemotherapy [PDF]

open access: yesDefinitions, 2020
In the past, patients with peritoneal metastases have been treated only with palliative thera -py. Their state was deemed to be incurable. The median survival time was approximately two months.
Yuranga Weerakkody   +2 more
semanticscholar   +3 more sources

Intraperitoneal Chemotherapy of Ovarian Cancer [PDF]

open access: goldWomen's Health, 2007
Ovarian cancer is the leading cause of death among cancers of the female reproductive tract. Most women present with regionally advanced intraperitoneal disease with superficial spread of tumor along the peritoneal surfaces. Distant metastasis rarely occurs until late in the disease process; however, long-term survival of patients with advanced ...
T. E. Lowe, Robert J. Morgan
openalex   +3 more sources

Intraperitoneal chemotherapy for peritoneal metastases : an expert opinion

open access: yesExpert Opinion on Drug Delivery, 2020
Introduction: The rationale for intraperitoneal (IP) drug delivery for patients with peritoneal metastases (PM) is based on the pharmacokinetic advantage resulting from the peritoneal-plasma barrier, and on the potential to adequately treat small, poorly
Braet, Helena   +4 more
core   +2 more sources

Efficacy and safety of intraperitoneal chemotherapy for pancreatic cancer [PDF]

open access: yesBMC Surgery
Pancreatic cancer is a highly aggressive cancer with unfavorable prognosis despite the therapeutic interventions. Intraperitoneal chemotherapy has recently shown potential outcomes in the presence of peritoneal metastases.
Dorsa Safari   +2 more
doaj   +2 more sources

Hyperthermic Intraperitoneal Chemotherapy in Ovarian Cancer

open access: yesDiagnostics, 2020
Hyperthermic intraperitoneal chemotherapy (HIPEC) in conjunction with cytoreductive surgery (CRS) holds promise as an adjunctive treatment strategy in malignancies affecting the peritoneal surface, effectively targeting remaining microscopic residual ...
McKayla J. Riggs   +3 more
doaj   +2 more sources

Hyperthermic intraperitoneal chemotherapy as consolidation treatment of advanced stage ovarian cancer [PDF]

open access: yesObstetrics & Gynecology Science, 2021
Objective To investigate the therapeutic efficacy of hyperthermic intraperitoneal chemotherapy (HIPEC) as consolidation treatment after completing first-line treatment in patients with advanced ovarian cancer.
Jieun Ko   +8 more
doaj   +1 more source

Pretreatment with VEGF(R)-inhibitors reduces interstitial fluid pressure, increases intraperitoneal chemotherapy drug penetration, and impedes tumor growth in a mouse colorectal carcinomatosis model [PDF]

open access: yes, 2015
Cytoreductive surgery combined with intraperitoneal chemotherapy (IPC) is currently the standard treatment for selected patients with peritoneal carcinomatosis of colorectal cancer.
Ceelen, Wim   +6 more
core   +11 more sources

Is intraperitoneal chemotherapy beneficial in pancreatic cancer? [PDF]

open access: yesRomanian Journal of Medical Practice, 2022
The role of intraperitoneal chemotherapy has been widely investigated in locally advanced malignancies which serosal involvement as well as in cases in which disseminated peritoneal nodules are present. However, its benefits have been widely contested by
Irina Balescu   +7 more
doaj   +1 more source

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