Results 131 to 140 of about 24,723 (162)

Analysis of Risk Factors Related to Carotid Artery in Patients with Acute Ischemic Stroke. [PDF]

Curr Med Imaging
Xiao D, Nie H, Xiao Y, Chen L, Zhang Y.
europepmc   +1 more source

Synergizing Systemic Inflammation and Multimodal Ultrasound: Methodological Insights Into Predicting Carotid Plaque Vulnerability. [PDF]

J Ultrasound Med
Lu H, Wang T.
europepmc   +1 more source

Intraplaque neovascularization as a novel therapeutic target in advanced atherosclerosis [PDF]

Expert Opinion on Therapeutic Targets, 2016
Atherosclerosis is a lipid-driven inflammatory process with a tremendously high mortality due to acute cardiac events. There is an emerging need for new therapies to stabilize atherosclerotic lesions. Growing evidence suggests that intraplaque (IP) neovascularisation and IP hemorrhages are important contributors to plaque instability.Neovascularization
Wim Martinet
exaly   +4 more sources

Role of lipids and intraplaque hypoxia in the formation of neovascularization in atherosclerosis

Annals of Medicine, 2017
According to the current paradigm, chronic vascular inflammation plays a central role in the pathogenesis of atherosclerosis. The plaque progression is typically completed with rupture and subsequent acute cardiovascular complications. Previously, the role of adventitial vasa vasorum in atherogenesis was underestimated.
Veronika Myasoedova, Dimitry Chistiakov, Alexander Orekhov   +2 more
exaly   +3 more sources

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Pharmacological interventions for intraplaque neovascularization in atherosclerosis

Pharmacology & Therapeutics
Advanced atherosclerosis is linked to plaque instability, which can result in rupture and the onset of a heart attack. Evidence gathered from human atheroma plaques indicates that intraplaque neovascularization poses a risk to plaque stability and may lead to plaque hemorrhage.
Nur Najmi Mohamad Anuar, Azizah Ugusman
exaly   +4 more sources

CCL14 exacerbates intraplaque vulnerability by promoting neovascularization in the human carotid plaque

Journal of Stroke and Cerebrovascular Diseases, 2022
To examine the role of CCL14 in the neovascularization process and vulnerability progression within carotid plaques by investigating the mechanism of CCL14 regulation of VEGF-A.We first performed histological analysis and immunohistochemical staining of human carotid plaque tissue to detect the expression of CCL14, JAK2, STAT3 and VEGF-A.
Zhuo Li, Zhen Qin, Xiangyi Kong, Baiqiang Chen, Wenjie Hu, Zhiqi Lin, Yugong Feng, Huanting Li, Qi Wan, Shifang Li   +9 more
openaire   +2 more sources

Carotid intraplaque hemorrhage: The significance of neovascularity

Journal of Vascular Surgery, 1987
Renewed interest in the neovascularity of atherosclerotic plaques has followed the work of Imparato et al., which confirmed the importance of carotid intraplaque hemorrhage in the production of symptomatic extracranial vascular disease. We have studied the detailed histology of 91 carotid atheromatous plaques with particular regard to hemorrhage and ...
J A, Fryer, P C, Myers, M, Appleberg
openaire   +2 more sources

Relationship between carotid intraplaque neovascularization and haemoglobin A1c in diabetic patients

Clinical Neurology and Neurosurgery, 2021
We aimed to evaluate the characteristics of carotid artery plaques and the relationship between intraplaque neovascularization (IPN) and hemoglobin A1c (HbA1c) in patients of
Yan, Song, Ying, Dang, Hao, Li, Jun, Feng, Litao, Ruan   +4 more
exaly   +3 more sources

Intraplaque neovascularization and hemorrhage

Journal of Cardiovascular Medicine, 2012
Atherosclerotic disease results in major clinical events and remains a leading cause of morbidity and mortality in the western World. Atherosclerotic plaques have a heterogeneous presentation. Atherosclerotic plaques with a vulnerable phenotype have been associated with an increased risk for cardiovascular complications.
Dave, Koole, Jan, Heyligers, Frans L, Moll, Gerard, Pasterkamp   +3 more
openaire   +2 more sources