Results 11 to 20 of about 1,759 (164)

Partial Inhibition of Glycolysis Reduces Atherogenesis Independent of Intraplaque Neovascularization in Mice. [PDF]

Arterioscler Thromb Vasc Biol, 2020
Objective: Intraplaque neovascularization is an important feature of unstable human atherosclerotic plaques. However, its impact on plaque formation and stability is poorly studied. Because proliferating endothelial cells generate up to 85% of their ATP from glycolysis, we investigated whether pharmacological inhibition of ...
Perrotta P, Van der Veken B, Van Der Veken P, Pintelon I, Roosens L, Adriaenssens E, Timmerman V, Guns PJ, De Meyer GRY, Martinet W.   +9 more
europepmc   +8 more sources

Added Clinical Value of Intraplaque Neovascularization Detection to Color Doppler Ultrasound for Assessing Ischemic Stroke Risk [PDF]

Neuropsychiatric Disease and Treatment
Liuping Cui,1,2 Ran Liu,1 Fubo Zhou,1 Yumei Liu,1 Bing Tian,1 Ying Chen,2,* Yingqi Xing1,3,4,* 1Department of Vascular Ultrasound, Xuanwu Hospital, Capital Medical University, Beijing, People’s Republic of China; 2Department of Neurology, The ...
Cui L, Liu R, Zhou F, Liu Y, Tian B, Chen Y, Xing Y   +6 more
doaj   +4 more sources

Consistency of superb microvascular imaging and contrast-enhanced ultrasonography in detection of intraplaque neovascularization: A meta-analysis. [PDF]

PLoS ONE, 2020
This meta-analysis assesses the consistency of superb microvascular imaging (SMI) and contrast-enhanced ultrasonography (CEUS) in detecting intraplaque neovascularization (IPN). We searched PubMed, Web of Science, the Cochrane Library, and CBM databases.
Fang Yang, Cong Wang
doaj   +3 more sources

Identification of neovascularization by contrast-enhanced ultrasound to detect unstable carotid stenosis. [PDF]

PLoS ONE, 2017
Plaque neovascularization accompanies local inflammation and critically contributes to plaque instability. Correct identification of intraplaque neovascularization by contrast-enhanced ultrasound (CEUS) may provide an additional risk marker in carotid ...
Charlotte Schmidt, Thomas Fischer, Ralph-Ingo Rückert, Timm Oberwahrenbrock, Lutz Harms, Golo Kronenberg, Hagen Kunte   +6 more
doaj   +3 more sources

Intraplaque neovascularization as a novel therapeutic target in advanced atherosclerosis [PDF]

Expert Opinion on Therapeutic Targets, 2016
Atherosclerosis is a lipid-driven inflammatory process with a tremendously high mortality due to acute cardiac events. There is an emerging need for new therapies to stabilize atherosclerotic lesions. Growing evidence suggests that intraplaque (IP) neovascularisation and IP hemorrhages are important contributors to plaque instability.Neovascularization
Van der Veken, Bieke, De Meyer, Guido R.Y., Martinet, Wim   +2 more
openaire   +3 more sources

Three-Dimensional Imaging of Intraplaque Neovascularization in a Mouse Model of Advanced Atherosclerosis

Journal of Vascular Research, 2020
Multiple lines of evidence suggest that intraplaque (IP) neovascularization promotes atherosclerotic plaque growth, destabilization, and rupture. However, pharmacological inhibition of IP neovascularization remains largely unexplored due to the limited number of animal models that develop IP neovessels and the lack of reliable methods for visualizing ...
Perrotta, P., Pintelon, I., Vries, M.R. de, Quax, P.H.A., Timmermans, J.P., Meyer, G.R.Y. de, Martinet, W.   +6 more
openaire   +7 more sources

Carotid intraplaque neovascularization for predicting ischemic cerebrovascular events in patients with hypertension. [PDF]

Quant Imaging Med Surg
Patients with hypertension are prone to developing carotid atherosclerotic plaques, and unstable plaques are a key contributor to ischemic cerebrovascular events (ICEs), including transient ischemic attacks (TIAs) and ischemic strokes. Intraplaque neovascularization (IPN), the formation of microvessels within plaques, is a recognized marker of plaque ...
Mi Y, Yang L, Jin X.
europepmc   +3 more sources

Impact of H-Type Hypertension on Intraplaque Neovascularization Assessed by Contrast-Enhanced Ultrasound. [PDF]

J Atheroscler Thromb, 2022
H-type hypertension is connected with carotid atherosclerotic plaques and stroke, whereas neovascularization is a dominant contributor to plaque vulnerability. However, the correlation between H-type hypertension and plaque vulnerability remains unclear.
Tan Y, Nie F, Wu G, Guo F, Wang Y, Wang L.   +5 more
europepmc   +4 more sources

Contrast-Enhanced Ultrasound Imaging of Intraplaque Neovascularization in Carotid Arteries

Journal of the American College of Cardiology, 2008
n ...
Coli, Stefano, Magnoni, Marco, Sangiorgi, Giuseppe, Marrocco-Trischitta, Massimiliano M., Melisurgo, Giulio, Mauriello, Alessandro, Spagnoli, Luigi, Chiesa, Roberto, Cianflone, Domenico, Maseri, Attilio   +9 more
core   +4 more sources

Association between fibrinogen-to-albumin ratio and carotid intraplaque neovascularization on AngioPLUS in patients with asymptomatic carotid stenosis [PDF]

Clinics
Introduction  The importance of the Fibrinogen-to-Albumin Ratio (FAR) as a novel inflammatory and thrombotic biomarker in the development of carotid Intraplaque Neovascularization (IPN) is not well understood.
Shugang Cao, Mingwu Xia, Jun He
exaly   +3 more sources