Results 11 to 20 of about 24,723 (162)

Incremental clinical value of intraplaque neovascularization in predicting recurrent ischemic stroke [PDF]

Annals of Clinical and Translational Neurology
Objective Carotid intraplaque neovascularization (IPN) detected by contrast‐enhanced ultrasound (CEUS) is a risk factor for recurrent ischemic stroke.
Liuping Cui, Ran Liu, Fubo Zhou, Bing Tian, Ying Chen, Yingqi Xing   +5 more
doaj   +4 more sources

Identification of neovascularization by contrast-enhanced ultrasound to detect unstable carotid stenosis. [PDF]

PLoS ONE, 2017
Plaque neovascularization accompanies local inflammation and critically contributes to plaque instability. Correct identification of intraplaque neovascularization by contrast-enhanced ultrasound (CEUS) may provide an additional risk marker in carotid ...
Charlotte Schmidt, Thomas Fischer, Ralph-Ingo Rückert, Timm Oberwahrenbrock, Lutz Harms, Golo Kronenberg, Hagen Kunte   +6 more
doaj   +9 more sources

Semaphorin 7A Promotes VEGFA/VEGFR2-Mediated Angiogenesis and Intraplaque Neovascularization in ApoE-/- Mice [PDF]

Frontiers in Physiology, 2018
Excessive neovascularization of atherosclerotic lesions increases plaque vulnerability and the susceptibility to rupture. Semaphorin 7A (Sema7A), a semaphorin family member, was recently reported to promote atherosclerotic plaque formation by mediating d-
Shuhong Hu, Yifei Liu, Tao You, Li Zhu
doaj   +5 more sources

Partial Inhibition of Glycolysis Reduces Atherogenesis Independent of Intraplaque Neovascularization in Mice. [PDF]

Arterioscler Thromb Vasc Biol, 2020
Objective: Intraplaque neovascularization is an important feature of unstable human atherosclerotic plaques. However, its impact on plaque formation and stability is poorly studied. Because proliferating endothelial cells generate up to 85% of their ATP from glycolysis, we investigated whether pharmacological inhibition of ...
Perrotta P, Van der Veken B, Van Der Veken P, Pintelon I, Roosens L, Adriaenssens E, Timmerman V, Guns PJ, De Meyer GRY, Martinet W.   +9 more
europepmc   +8 more sources

Carotid Intraplaque Neovascularization Quantification Software (CINQS)

IEEE Journal of Biomedical and Health Informatics, 2015
Intraplaque neovascularization (IPN) is an important biomarker of atherosclerotic plaque vulnerability. As IPN can be detected by contrast enhanced ultrasound (CEUS), imaging-biomarkers derived from CEUS may allow early prediction of plaque vulnerability.
Zeynettin Akkus, Gerard van Burken, Stijn C. H. van den Oord, Arend F. L. Schinkel, Nico de Jong, Antonius F. W. van der Steen, Johan G. Bosch   +6 more
openaire   +3 more sources

Contrast-Enhanced Ultrasound Imaging of Intraplaque Neovascularization in Carotid Arteries [PDF]

Journal of the American College of Cardiology, 2008
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Coli, Stefano, Magnoni, Marco, Sangiorgi, Giuseppe, Marrocco-Trischitta, Massimiliano M., Melisurgo, Giulio, Mauriello, Alessandro, Spagnoli, Luigi, Chiesa, Roberto, Cianflone, Domenico, Maseri, Attilio   +9 more
core   +4 more sources

Contrast-Enhanced Ultrasound Imaging Detects Intraplaque Neovascularization in an Experimental Model of Atherosclerosis [PDF]

JACC: Cardiovascular Imaging, 2010
The aims of this study were to investigate the feasibility of contrast-enhanced ultrasound (CEU) imaging for in vivo visualization of intraplaque neovascularization and to correlate the in vivo observations with histological assessment of neovessel density and plaque composition in an experimental animal model of advanced atherosclerosis.Recent ...
Giannarelli, Chiara, Ibanez, Borja, CIMMINO, Giovanni, Garcia Ruiz, Jos M., Faita, Francesco, Bianchini, Elisabetta, Zafar, M. Urooj, Fuster, Valentin, Garcia, Mario J., Badimon, Juan J.   +9 more
openaire   +5 more sources

Three-Dimensional Imaging of Intraplaque Neovascularization in a Mouse Model of Advanced Atherosclerosis [PDF]

Journal of Vascular Research, 2020
Multiple lines of evidence suggest that intraplaque (IP) neovascularization promotes atherosclerotic plaque growth, destabilization, and rupture. However, pharmacological inhibition of IP neovascularization remains largely unexplored due to the limited number of animal models that develop IP neovessels and the lack of reliable methods for visualizing ...
Perrotta, P., Pintelon, I., Vries, M.R. de, Quax, P.H.A., Timmermans, J.P., Meyer, G.R.Y. de, Martinet, W.   +6 more
openaire   +6 more sources

AngioPLUS-derived carotid intraplaque neovascularization predicts recurrent anterior circulation stroke: a prospective cohort study [PDF]

Frontiers in Neurology
Background and purposeThe predictive value of carotid intraplaque neovascularization (IPN), assessed by the novel AngioPLUS technique, for recurrent anterior circulation ischemic stroke (ACIS) remains unclear.
Hao Zhang, Jun He, Jimei Xu, Rongfeng Wang, Shugang Cao, Mingwu Xia   +5 more
doaj   +2 more sources

Retrospective study on the association between carotid plaque stability assessed by ultrasound imaging features and stroke risk [PDF]

Frontiers in Neurology
BackgroundCarotid plaque instability is a critical determinant of ischemic stroke risk. Identifying ultrasound imaging features associated with plaque vulnerability may enhance stroke risk stratification.MethodsThis retrospective cohort study evaluated ...
Bo Wang, Yingjun Li, LiSha Qiu
doaj   +2 more sources