Results 21 to 30 of about 1,759 (164)

Role of lipids and intraplaque hypoxia in the formation of neovascularization in atherosclerosis

Annals of Medicine, 2017
According to the current paradigm, chronic vascular inflammation plays a central role in the pathogenesis of atherosclerosis. The plaque progression is typically completed with rupture and subsequent acute cardiovascular complications. Previously, the role of adventitial vasa vasorum in atherogenesis was underestimated.
Dimitry A Chistiakov, Alexandra A Melnichenko, Veronika A Myasoedova   +2 more
exaly   +3 more sources

The Monocyte-to-Lymphocyte Ratio Was Associated With Intraplaque Neovascularization of the Carotid Artery on AngioPLUS. [PDF]

Brain Behav
ABSTRACT Background The monocyte–lymphocyte ratio (MLR) is a hematological test parameter that reflects the status of both monocytes and lymphocytes as inflammatory cells. This study aims to investigate the relationship between MLR and carotid intraplaque neovascularization (IPN) in patients ...
Zhai M, Sun X, Wang J, Xu J, Bian F, Wu M, Yang Y, Chen H, Lu J.   +8 more
europepmc   +4 more sources

Carotid intraplaque neovascularization predicts coronary artery disease and cardiovascular events. [PDF]

Eur Heart J Cardiovasc Imaging, 2019
Abstract Aims It is thought that the majority of cardiovascular (CV) events are caused by vulnerable plaque. Such lesions are rupture prone, in part due to neovascularization. It is postulated that plaque vulnerability may be a systemic process and that vulnerable lesions may co-exist at multiple ...
Mantella LE, Colledanchise KN, Hétu MF, Feinstein SB, Abunassar J, Johri AM.   +5 more
europepmc   +4 more sources

Contrast-Enhanced Ultrasound Imaging Detects Intraplaque Neovascularization in an Experimental Model of Atherosclerosis

JACC: Cardiovascular Imaging, 2010
The aims of this study were to investigate the feasibility of contrast-enhanced ultrasound (CEU) imaging for in vivo visualization of intraplaque neovascularization and to correlate the in vivo observations with histological assessment of neovessel density and plaque composition in an experimental animal model of advanced atherosclerosis.Recent ...
Giannarelli, Chiara, Ibanez, Borja, CIMMINO, Giovanni, Garcia Ruiz, Jos M., Faita, Francesco, Bianchini, Elisabetta, Zafar, M. Urooj, Fuster, Valentin, Garcia, Mario J., Badimon, Juan J.   +9 more
openaire   +5 more sources

Data on consistency among different methods to assess atherosclerotic plaque echogenicity on standard ultrasound and intraplaque neovascularization on contrast-enhanced ultrasound imaging in human carotid artery

Data in Brief, 2016
Here we provide the correlation among different carotid ultrasound (US) variables to assess echogenicity n standard carotid US and to assess intraplaque neovascularization on contrast enhanced US. We recruited 45 consecutive subjects with an asymptomatic≥
Mattia Cattaneo, Daniel Staub, Alessandra P. Porretta, Jeanne Marie Gallino, Paolo Santini, Costanzo Limoni, Rolf Wyttenbach, Augusto Gallino   +7 more
doaj   +2 more sources

Retrospective study on the association between carotid plaque stability assessed by ultrasound imaging features and stroke risk [PDF]

Frontiers in Neurology
BackgroundCarotid plaque instability is a critical determinant of ischemic stroke risk. Identifying ultrasound imaging features associated with plaque vulnerability may enhance stroke risk stratification.MethodsThis retrospective cohort study evaluated ...
Bo Wang, Yingjun Li, LiSha Qiu
doaj   +2 more sources

Endothelial ADAM10 controls cellular response to oxLDL and its deficiency exacerbates atherosclerosis with intraplaque hemorrhage and neovascularization in mice [PDF]

Frontiers in Cardiovascular Medicine, 2023
IntroductionThe transmembrane protease A Disintegrin And Metalloproteinase 10 (ADAM10) displays a “pattern regulatory function,” by cleaving a range of membrane-bound proteins.
Emiel P. C. van der Vorst, Emiel P. C. van der Vorst, Emiel P. C. van der Vorst, Emiel P. C. van der Vorst, Emiel P. C. van der Vorst, Sanne L. Maas, Sanne L. Maas, Kosta Theodorou, Linsey J. F. Peters, Linsey J. F. Peters, Linsey J. F. Peters, Han Jin, Timo Rademakers, Marion J. Gijbels, Marion J. Gijbels, Marion J. Gijbels, Mat Rousch, Yvonne Jansen, Christian Weber, Christian Weber, Christian Weber, Michael Lehrke, Corinna Lebherz, Daniela Yildiz, Daniela Yildiz, Andreas Ludwig, Jacob F. Bentzon, Jacob F. Bentzon, Erik A. L. Biessen, Erik A. L. Biessen, Marjo M. P. C. Donners   +30 more
doaj   +5 more sources

Inflammatory Neovascularization and Vascular Remodeling Associated With Carotid Plaque Destabilization. [PDF]

CNS Neurosci Ther
A subset of endothelial cells in the AC region promoted neovascularization, while the PA region exhibited an increase in osteogenic VSMCs, contributing to vascular remodeling. Fibroblast‐mediated inflammatory regulation was predominantly enriched in the PA region, whereas the AC region harbored more macrophage subsets involved in lipid metabolism and ...
Dai X, Huang J, Ni F, Hu R, Zheng H, Wang D, Zhang J, Sun T.   +7 more
europepmc   +2 more sources

Assessment of Carotid Intraplaque Neovascularization Using Superb Microvascular Imaging in High Risk of Stroke Individuals: Results From a Community-Based Study [PDF]

Frontiers in Neurology, 2019
Background: Improved stroke risk stratification may improve stroke prevention. We aimed to study the value of a novel Doppler method, superb microvascular imaging (SMI), in correlating plaque thickness and evidence of intra-plaque neovascularization with
Ying Wang, Ming Yao, Mi Zou, Shengde Li, Zhitong Ge, Yuehui Hong, Siman Cai, Hongyan Wang, Jianchu Li   +8 more
doaj   +2 more sources

Improved stroke risk stratification in carotid atherosclerosis: integrating intraplaque neovascularization into Carotid Plaque-RADS [PDF]

BMC Medical Imaging
Introduction This study evaluates whether IPN, as assessed by contrast-enhanced ultrasound (CEUS), enhances stroke risk stratification within the Carotid Plaque-RADS framework.
Zhe Huang, Xue-Qing Cheng, Rui-Rui Lu, Xiao-Jun Bi, Ya-Ni Liu, You-Bin Deng   +5 more
doaj   +2 more sources