Results 51 to 60 of about 24,723 (162)

Circulating Serum AGRN and ADAMTS8 With Related Candidates as Potential Biomarkers for Carotid Plaque Presence and Vulnerability

CNS Neuroscience &Therapeutics, Volume 32, Issue 9, September 2026.
This study investigated serum AGRN and ADAMTS8 as biomarkers for carotid plaques within human participants. Results showed a significant correlation with plaque presence, yielding a moderate combined diagnostic performance. However, these markers poorly differentiated plaque vulnerability.
Shuaiwei Guo, Shengyan Cui, Xiao Zhang, Zixuan Xing, Yixin Sun, Mingqian Qin, Xiaoying Ma, Xiangyu Li, Yan Ma, Peng Gao, Yanfei Chen, Yabing Wang, Bin Yang, Jian Chen, Fei Chen, Xia Lu, Jiaqi Jin, Liqun Jiao, Tao Wang   +18 more
wiley   +1 more source

Relation between carotid vulnerable plaques and peripheral leukocyte: a case-control study of comparison utilizing multi-parametric contrast-enhanced ultrasound

BMC Medical Imaging, 2019
Background This study evaluates carotid vulnerable plaques using contrast-enhanced ultrasound (CEUS) and explores the relationship between vulnerable plaques and leukocytes. Methods Sixty-two symptomatic and 54 asymptomatic patients underwent CEUS.
Xianghong Luo, Wanbin Li, Yun Bai, Lianfang Du, Rong Wu, Zhaojun Li   +5 more
doaj   +1 more source

Advances in FGF/FGFR Signaling: Implications for Disease and Therapy

MedComm, Volume 7, Issue 9, September 2026.
The FGF/FGFR signaling is indispensable for the maintenance of physiological homeostasis and governs multiple biological processes, including embryonic development, bone metabolism, angiogenesis, and neurogenesis, whereas aberrant hyperactivation of this pathway drives the progression of malignancies and autoimmune disorders, including inflammatory ...
Miaoyu Song, Xi Liu, Yang Xiao, Yongsheng Li, Huakan Zhao   +4 more
wiley   +1 more source

Plaque angiogenesis and intraplaque hemorrhage in atherosclerosis. [PDF]

, 2017
Acute cardiovascular events, due to rupture or erosion of an atherosclerotic plaque, represent the major cause of morbidity and mortality in patients. Growing evidence suggests that plaque neovascularization is an important contributor to plaque growth ...
Paul H.A. Quax, Fabiana Baganha, Margreet R. de Vries, Vries, M.R. de, Laura Parma, Quax, P.H.A., Margreet R de Vries, Parma, L., Paul HA Quax, Baganha, F.   +9 more
core   +1 more source

Lymphatic Endothelial Cells in Health and Disease

MedComm, Volume 7, Issue 8, August 2026.
Lymphatic endothelial cells (LECs) are dynamic regulators of tissue homeostasis and disease remodeling. In the healthy state, LECs coordinate interstitial fluid drainage, intestinal lipid transport, and immune trafficking and tolerance. Across disease settings, however, these same programs become maladaptively reprogrammed, contributing to barrier ...
Du Tang, Wang Lin, Hengyang Liu, Jixin Zhong, Shiliang Li, Xiaoquan Rao   +5 more
wiley   +1 more source

Atherosclerotic Cardiovascular Disease and Cancer

Immunological Reviews, Volume 340, Issue 1, July 2026.
ABSTRACT Atherosclerotic cardiovascular disease (ASCVD) and cancer are increasingly recognized as interconnected diseases linked by shared immune mechanisms rather than merely overlapping risk factors. Common exposures such as smoking, obesity, diabetes, and dyslipidemia, together with aging and clonal hematopoiesis of indeterminate potential (CHIP ...
Anaïs Amend, Hauke Horstmann, Kory J. Lavine, Chiara Giannarelli, Kathryn J. Moore   +4 more
wiley   +1 more source

Novel Imaging-Based Biomarkers for Identifying Carotid Plaque Vulnerability

Biomolecules, 2023
Carotid artery disease has traditionally been assessed based on the degree of luminal narrowing. However, this approach, which solely relies on carotid stenosis, is currently being questioned with regard to modern risk stratification approaches.
Verónica Fernández-Alvarez, Miriam Linares-Sánchez, Carlos Suárez, Fernando López, Orlando Guntinas-Lichius, Antti A. Mäkitie, Patrick J. Bradley, Alfio Ferlito   +7 more
doaj   +1 more source

Inflammatory Neovascularization and Vascular Remodeling Associated With Carotid Plaque Destabilization

CNS Neuroscience &Therapeutics, Volume 32, Issue 6, June 2026.
A subset of endothelial cells in the AC region promoted neovascularization, while the PA region exhibited an increase in osteogenic VSMCs, contributing to vascular remodeling. Fibroblast‐mediated inflammatory regulation was predominantly enriched in the PA region, whereas the AC region harbored more macrophage subsets involved in lipid metabolism and ...
Xuejiao Dai, Jia Huang, Feihua Ni, Ruying Hu, Huiyan Zheng, Dan Wang, Jianqiao Zhang, Ting Sun   +7 more
wiley   +1 more source

Assessment of Carotid Plaque Stability Using Contrast-Enhanced Ultrasound and Its Correlation With the Expression of CD147 and MMP-9 in the Plaque

Frontiers in Computational Neuroscience, 2021
This study aims to investigate the correlation between the enhancement degree of contrast-enhanced ultrasound (CEUS) and the expression of CD147 and MMP-9 in carotid atherosclerotic plaques in patients with carotid endarterectomy and evaluate the ...
Shanshan Huang, Xinyin Wu, Linlin Zhang, Jianming Wu, Yi He, Manlin Lai, Jiaqi Xu, Zhenzhou Li   +7 more
doaj   +1 more source

Nanotherapies for Atherosclerosis: Targeting, Catalysis, and Energy Transduction

Advanced Healthcare Materials, Volume 15, Issue 20, 27 May 2026.
Atherosclerosis management is hindered by poor drug targeting and plaque heterogeneity. Nanotechnology overcomes these barriers via three core strategies: (1) target‐engineered nanocarriers that achieve lesion‐specific precision via ligand modification, biomimetic camouflage, stimuli‐responsive release, and self‐propelling nanomotors; (2) catalytic ...
Yuqi Yang, Jingguo Qu, Tonghuan Xiao, Xinyang Han, Michael Tin‐Cheung Ying   +4 more
wiley   +1 more source