Results 161 to 170 of about 10,244 (214)

Intrathecal morphine in mice: A new technique

European Journal of Pharmacology, 1980
A simple, rapid technique for intrathecal injections by lumbar puncture in unanesthetized mice is described. Intrathecal [3H]morphine base was not found in significant quantities in either the midbrain or forebrain. Submicrogram quantities of morphine sulfate induced Straub tail response and tail-flick analgesia.
George L Wilcox
exaly   +3 more sources

Intrathecal morphine in anesthesia for cesarean delivery: dose-response relationship for combinations of low-dose intrathecal morphine and spinal bupivacaine

Journal of Clinical Anesthesia, 2008
Study objective: To evaluate the quality of analgesia and the severity of side effects of intrathecal morphine administered for a dose range of 0.0 to 0.4 mg for postcesarean analgesia with low-dose bupivacaine. Design: Double-blind, randomized study.
Alp Gurbet, Gurkan Türker, Hale Aksu
exaly   +3 more sources

Interaction Between Spinal Opioid and Adenosine Receptors in Remote Cardiac Preconditioning: Effect of Intrathecal Morphine

Journal of Cardiothoracic and Vascular Anesthesia, 2011
OBJECTIVES: Intrathecal morphine is cardioprotective and also triggers spinal adenosine release. This study investigated the role of spinal and peripheral adenosine receptors in intrathecal morphine cardioprotection.
G T C Wong, Michael Garnet Irwin
exaly   +2 more sources

Intrathecal morphine overdose in a dog

Journal of the American Veterinary Medical Association, 2007
Abstract Case Description—A healthy 6-year-old 28.5-kg (62.7-lb) spayed female Boxer undergoing surgical repair of a ruptured cranial cruciate ligament was inadvertently administered an overdose of morphine (1.3 mg/kg [0.59 mg/lb]) via subarachnoid injection.
Anderson F, da Cunha, Jennifer E, Carter, Michael, Grafinger, Heather, Montgomery, Steven L, Marks, Lysa P, Posner, Patrick, Burns   +6 more
openaire   +2 more sources

Driving and intrathecal morphine administration

European Journal of Pain, 2001
Since Belgian law recently set a limit to morphine concentration detectable in blood and urine while driving a vehicle, questions arose about the implications for the medical use of opiates. We determined morphine concentrations in whole blood and urine by gas chromatography–mass spectrometry in 15 patients on continuous intrathecal morphine ...
van den Bosch, G., de Doncker, M., Vercruysse, P., Maeyaert, J., Vissers, K., Neels, H.   +5 more
openaire   +3 more sources

Intrathecal Morphine After Cardiac Surgery

The Annals of Pharmacotherapy, 2002
OBJECTIVE: To assess whether intrathecal (IT) analgesia facilitates early extubation and provides superior pain control after cardiac surgery compared with patient-controlled analgesia (PCA) or nurse-administered SC injections. METHODS:
Aline, Boulanger, Sylvie, Perreault, Manon, Choinière, Ignacio, Priéto, Claire, Lavoie, Claude, Laflamme   +5 more
openaire   +2 more sources

Intrathecal Morphine for Spinal Fusion in Children

Spine, 1988
Intrathecal morphine (0.025 mg/kg) was administered preoperatively to 20 children undergoing major surgery of the rachis, ie, either posterior (16 cases) or anterior (4 cases) spinal fusions. During the surgical procedure, hemodynamic control was easily maintained.
B, Dalens, A, Tanguy
openaire   +2 more sources

Hypogonadism in Patients Treated With Intrathecal Morphine

The Clinical Journal of Pain, 2000
The objective of this study was to investigate the hypothalamic-pituitary-gonadal response to intrathecal opioids.Thirty patients receiving intrathecal morphine for chronic nonmalignant pain were studied for clinical and biochemical evidence of hypogonadism.
P M, Finch, L J, Roberts, L, Price, N C, Hadlow, P T, Pullan   +4 more
openaire   +2 more sources

Chronically Infused Intrathecal Morphine in Dogs

Anesthesiology, 2003
Background Despite the extensive use of intrathecal morphine infusion for pain, no systematic safety studies exist on its effects in high concentrations. The authors assessed the effects of morphine and clonidine given 28 days intrathecally in dogs.
Tony L, Yaksh, Kjersti A, Horais, Nicolle A, Tozier, Jeffrey W, Allen, Michael, Rathbun, Steven S, Rossi, Claudia, Sommer, Carol, Meschter, Philip J, Richter, Keith R, Hildebrand   +9 more
openaire   +2 more sources

Chronic intrathecal morphine for intractable pain

Journal of Neurosurgery, 1987
✓ Forty-three patients with intractable pain received intrathecal morphine delivered by implanted continuous-infusion (Infusaid) or programmable (Medtronic) devices. In 35 patients the pain was due to cancer, and eight patients had chronic nonmalignant pain.
R D, Penn, J A, Paice
openaire   +2 more sources