Results 131 to 140 of about 43,236 (245)

Inhaled Nanomedicines for Lung Diseases and Injuries: Pharmacological Advances and Clinical Translation

MedComm, Volume 7, Issue 11, November 2026.
Graphical overview of bioinspired regenerative platforms designed to remodel the diseased lung microenvironment. These systems integrate gene addition, siRNA‐mediated transcript silencing, CRISPR‐based modulation, and base editing approaches to promote alveolar repair, AT2‐to‐AT1 regeneration, resolution of inflammation, and restoration of vascular ...
Kajal Kamra, Sonal Gaur, Jaswinder Singh
wiley   +1 more source

Characterization of an intratracheal aerosol challenge model of Brucella melitensis in guinea pigs

, 2019
B. melitensis is considered the most virulent of the Brucella species, and a need exists for an improved laboratory animal model of infection that mimics natural transmission and disease. Guinea pigs are highly susceptible to infection with Brucella spp.
Daniel G. Garcia-Gonzalez (6425417), Daniel G Garcia-Gonzalez, Angela M Arenas-Gamboa, Martha E Hensel, Martha E. Hensel (6425414), James Samuel, James Samuel (364113), Angela M. Arenas-Gamboa (4372837), Sankar P Chaki, Sankar P. Chaki (6425420)   +9 more
core   +1 more source

The PIEZO1/CISD1/IP3R Mechanotransduction Axis Drives Macrophage Mitochondrial Dysfunction and Inflammatory Activation in Pulmonary Fibrosis

MedComm, Volume 7, Issue 11, November 2026.
In the pulmonary fibrotic microenvironment, mechanical signals activate PIEZO1 to mediate Ca2+ entry into macrophages. Increased CISD1/IP3R activity promotes Ca2+ transfer from the endoplasmic reticulum to mitochondria, leading to mitochondrial Ca2+ overload and opening of the mitochondrial permeability transition pore (MPTP). Consequently, macrophages
Yungeng Wei, Chao Xie, Xiangsheng Yang, Xiao Xiao Tang   +3 more
wiley   +1 more source

Systemic Immune Effects of Titanium Dioxide Nanoparticles after Repeated Intratracheal Instillation in Rat

, 2014
The potential immune effects of titanium dioxide nanoparticles (nano-TiO2) are raising concern. Our previous study verified that nano-TiO2 induce local immune response in lung tissue followed by intratracheal instillation administration.
Shumei Ma, Yanqiu Zhang, Yanyun Fu, Xuhong Chang, Lihong Yin, Geyu Liang, Yingjian Zhang, Jing Sui, Yuepu Pu   +8 more
core   +1 more source

Real‐World Safety and Effectiveness of Icatibant in Patients With Hereditary Angioedema (HAE): Post‐Marketing Surveillance in Japan

The Journal of Dermatology, Volume 53, Issue 11, Page 1599-1614, November 2026.
ABSTRACT Hereditary angioedema (HAE) is a rare, autosomal dominant, life‐threatening disease characterized by recurrent attacks of swelling of the face, upper airway, gastrointestinal tract, limbs, and/or genitalia. Genetic mutations of the SERPING1 gene encoding the C1‐inhibitor (C1‐INH) plasma protein are associated with HAE‐C1INH.
Kumiko Hosono, Miyako Hoshino
wiley   +1 more source

Microbial Characteristics of Weissella cibaria HRL3 and Its Immunostimulatory Effects via TLR3/TLR9‐Dependent IFN‐α Production

Journal of Food Science, Volume 91, Issue 11, November 2026.
ABSTRACT Rhinacanthus nasutus (L.) Kurz is a medicinal plant whose roots, stems, and leaves are commonly used in tea and traditional Chinese medicine; however, the beneficial effects of its flowers remain to be investigated. In this study, the lactic acid bacteria (LAB) found in the flowers of R.
Fumie Niitsuma, Hiroka Sasahara, Akihiro Masaki, Ayaha Toritani, Minako Tsukamoto, Tomoya Takahashi, Sachi Tanaka   +6 more
wiley   +1 more source

Intratracheal recombinant human deoxyribonuclease in acute life-threatening asthma refractory to conventional treatment

, 2000
Recombinant human deoxyribonuclease (rhDNase) is a mucolytic agent used to relieve peripheral airway obstruction in patients with cystic fibrosis. We report dramatic sustained improvement following the intratracheal administration of rhDNase to a 3-yr ...
Patel, A, Durward, A, Harrison, E, Murdoch, I A   +3 more
core   +3 more sources

EFFECT OF DOPED CERIUM OXIDE NANOPARTICLES ON THE HAEMATOLOGY OF RATS [PDF]

Journal of Veterinary and Animal Sciences, 2016
Cerium is a rare earth lanthanide and a strong oxidizing agent. It has got a wide range of application from engendering to medicinal field. Potential amount of harm also reported about this particle.
R. Sovan, N. Vijayan, C. B. Manomohan, V. Sajith, K. B. Dhanush   +4 more
doaj  

Inter‐Rater Reliability in Pre‐Anaesthetic Airway Assessment: A Protocol for a Systematic Review

Acta Anaesthesiologica Scandinavica, Volume 70, Issue 10, November 2026.
ABSTRACT Background Pre‐anaesthetic airway assessment relies on subjective clinical judgement, whether performed through direct physical examination, such as Mallampati classification or thyromental distance, or through composite scoring systems that combine several such components, including the Simplified Airway Risk Index, the El‐Ganzouri Risk Index
Constance Thyra Giertz Christiansen, Mathilde Nellemann Jensen, Moritz Kilian German Denneborg, Sofie Amalie Bosholdt, Janus Christian Jakobsen, Rasmus Tingkær Hesselfeldt, Morten Hylander Møller, Andreas Møgelmose, Markus Harboe Olsen, Michael Seltz Kristensen, Katrine Bredahl Buggeskov   +10 more
wiley   +1 more source

Ultrasound as a Tool in the Assessment of Airway Difficulties – A Cross-sectional Study

Airway
Background and Aims: Airway management is fundamental to safe anaesthetic practice and is of paramount importance. This study aimed to determine the ability of ultrasound (US) measurements of anterior neck soft-tissue thickness at various levels in ...
Gayathry Roy, Elizabeth Joseph
doaj   +1 more source