Results 111 to 120 of about 43,236 (245)

Potential of Ginkgo biloba Extract to Intervene in Chronic Inflammation‐Related Diseases

Phytotherapy Research, EarlyView.
Chronic inflammation is a pathological mechanism underpinning many diseases. Ginkgo biloba extract (GBE) is well known for its anti‐inflammatory property. GBE and its active constituents have been shown to attenuate pro‐inflammatory cytokine production, suppress nuclear factor kappa B activation, restore redox homeostasis, and modulate disease‐relevant
Yipeng Lin, Inho Cho, Xue Zhu, Ke Wang, Ling Zhu, Wenchang Wong, Michael Murray, Fanfan Zhou   +7 more
wiley   +1 more source

Biomaterial Platforms for Spatiotemporal Control of mRNA Delivery in Tissue Engineering and Regenerative Medicine: Design Rules, Therapeutic Applications, and Translational Roadmap

Small, EarlyView.
Biomaterial platforms can control where and when mRNA‐encoded proteins are expressed to support tissue repair. This Review proposes a cargo–target–timing framework linking therapeutic function, target tissues and cells, and expression profiles with carrier and scaffold design.
Huachun Pan, Shumin Yang, Katarina Holubova, Huifang Yin, Hongbo Chen, Xintian Zheng, Xiangan Han, Jinqiu Zhang, Xueping Li, Hui Zhang, Xiaojun Cai, Václav Slovák, Lihong Zhang, Quan Mo, Quazi T. H. Shubhra   +14 more
wiley   +1 more source

Classification of videolaryngoscopy: a systematic review

Anaesthesia, EarlyView.
Summary Introduction Structured classification and consistent documentation of videolaryngoscopy findings are essential for future airway planning. Although numerous classification tools for communication have been proposed, their accuracy and effectiveness remain uncertain.
Catharina Grün, André Dankert, Viktor A. Wünsch, Yasmin Engels, Aljoscha Ewert, Hans‐Heinrich Sieg, Lili Plümer, Christian Zöllner, Martin Petzoldt   +8 more
wiley   +1 more source

Establishment of a mouse model for pulmonary inflammation and fibrosis by intratracheal instillation of polyhexamethyleneguanidine phosphate

, 2016
Although several animal models have been developed to study human pulmonary fibrosis, lack of a perfect model has raised the need for various animal models of pulmonary fibrosis.
Dong-Jae Kim, Lee, Sang Jin, Park, Jong-Hwan, Jeong Ah Song, Kyuhong Lee, Jeong, Yu-Jin, Jong-Hwan Park, Jun-Young Lee, Lee, Jun-Young, Lee, Kyuhong, Kim, Dong-Jae, Song, Jeong Ah, Yu-Jin Jeong, Sang Jin Lee   +13 more
core   +1 more source

Learning and performance of endotracheal intubation by paramedical students: Comparison of GlideScope® and intubating laryngeal mask airway with direct laryngoscopy in manikins

Indian Journal of Anaesthesia, 2016
Background and Aims: GlideScope video laryngoscope (GVL) and intubating laryngeal mask airway (I-LMA) may be used to facilitate intubation and secure the airway in patients with normal and abnormal airways.
Adil Omar Bahathiq, Tharwat Helmy Abdelmontaleb, Mohammed Khairt Newigy   +2 more
doaj   +1 more source

Inhibition of the MER tyrosine kinase ameliorates pulmonary fibrosis by suppressing macrophage M2 polarisation and osteopontin signalling

British Journal of Pharmacology, EarlyView.
Background and Purpose The MER proto‐oncogene tyrosine kinase (MERTK) has been implicated in the pathogenesis of pulmonary fibrosis (PF), and MERTK inhibition has been shown to ameliorate PF. However, the mechanisms remain unclear. Here, we have investigated how MERTK inhibition attenuates bleomycin (BLM)‐induced PF in mice and to elucidate the ...
Juan Li, Xiangsheng Yang, Xiao Xiao Tang
wiley   +1 more source

Intratracheal administration of glucocorticoids using surfactant as a vehicle

, 2002
The definitive version is available at www.blackwell-synergy.com1. Glucocorticoids are an effective treatment in the amelioration of chronic lung disease in neonates.
Vink, R., Whitehall, John, Davidson, Kate, Patole, Sanjay K., Carstairs, Jill R., Davidson, K., Robert Vink, Alan J Nimmo, John Whitehall, Kate Davidson, Vink, Robert, Carstairs, J., Whitehall, J., Nimmo, A., Patole, S., Nimmo, Alan, Jill R Carstairs, Sanjay K Patole   +17 more
core   +1 more source

Human Embryonic Stem Cell‐Derived Immunity‐And‐Matrix‐Regulatory Cells Attenuate Pulmonary Fibrosis via MMP1‐Mediated Collagen Degradation

Cell Proliferation, EarlyView.
Human embryonic stem cell‐derived Immunity‐and‐Matrix‐Regulatory Cells (IMRCs) effectively attenuate pulmonary fibrosis by secreting Matrix Metalloproteinase‐1 (MMP1), which directly degrades excess collagen I in the extracellular matrix. By directly degrading collagen I, IMRCs reverse ECM stiffness, suppress myofibroblast activation, and promote a ...
Zhongwen Li, Dingyun Song, Faguo Sun, Licheng Song, Bin An, Tingting Gao, Jingjing Liu, Kan Zhang, Kaidi Liu, Kaiwei Wu, Yajing Li, Yi Yang, Yaru Liu, Ruofan Su, Zai Wang, Tiemei Zhao, Huaiyong Chen, Li Xiao, Liang Peng, Liu Wang, Wei Li, Lixin Xie, Jie Hao, Huaping Dai, Jun Wu   +24 more
wiley   +1 more source

Use of fibrin sealant in a horse with an intratracheal dorsal laceration

, 2020
Dorsal intratracheal laceration was diagnosed in a horse with severe subcutaneous emphysema. Due to the size of the defect and the severity of the symptoms, different methods were attempted to close the laceration.
Dahmen K., Munoz E., Fischer H., Bach N., Dylewski L., Coco L., Albanese V.   +6 more
core   +1 more source

Interleukin‐12: Central Roles in Immune Regulation and Disease Therapy

Immunology &Cell Biology, EarlyView.
IL‐12 levels are tightly regulated to balance effective protective immunity against infections and cancer with the risk of excessive inflammation and autoimmune disease. Both insufficient and excessive IL‐12 activity can therefore be detrimental, highlighting the importance of precisely controlling its production and signaling. ABSTRACT Interleukin‐12 (
Anthi Psoma, Geert van den Bogaart
wiley   +1 more source