Results 101 to 110 of about 43,236 (245)

INTRATRACHEAL PERFLUOROCARBON ADMINISTRATION COMBINED WITH MECHANICAL VENTILATION IN EXPERIMENTAL RESPIRATORY-DISTRESS SYNDROME - DOSE-DEPENDENT IMPROVEMENT OF GAS-EXCHANGE

, 1993
Objectives: To test the efficacy of intratracheal instillation of a perfluorocarbon, combined with conventional mechanical ventilation, as well as to establish the dose response of this application on pulmonary parameters in adult animals with acute ...
LACHMANN, B, TUTUNCU, AS, FAITHFULL, NS
core   +1 more source

Epigenetically Regulated NOX4/NRF2 Axis Mediates PM2.5‐Induced Ferroptosis and Inflammatory Response in Membranous Nephropathy

Journal of Applied Toxicology, EarlyView.
ABSTRACT This study aims to explore the involvement and mechanism of ferroptosis in particulate matter 2.5 (PM2.5)–induced membranous nephropathy (MN) progression. A cationic bovine serum albumin (cBSA)–induced mouse model of MN was established, followed by PM2.5 exposure.
Yanhong Gao, Yinfeng Guo, Shaoyan Xu, Min Zhang, Yanxia Rui, Shujun Pan, Changhua Zhou, Jianxiang Chen, Henglan Wu   +8 more
wiley   +1 more source

Effects of intratracheal mesenchymal stromal cell therapy during recovery and resolution after ventilator-induced lung injury

, 2018
Background: Mesenchymal stromal cells (MSCs) have been demonstrated to attenuate acute lung injury when delivered by intravenous or intratracheal routes.
Toole, Daniel O’, Ansari, Bilal, Devaney, James, Curley, Gerard F., Hayes, Mairead, Barry, Frank, O’Brien, Timothy, Laffey, John G., Masterson, Claire, Ryan, Aideen   +9 more
core  

Intratracheal instillation of corticosteroids combined with surfactant for preventing chronic lung disease in preterm infants

This is a protocol for a Cochrane Review (intervention). The objectives are as follows: Primary objective To evaluate the benefits and harms of intratracheal instillation of corticosteroids combined with surfactant versus surfactant alone for the ...
Pahl, Adrienne, Gautham, Kanekal S, Borys, Franciszek, Bolanos, Luis, Fiander, Michelle, Soll, Roger F, Cracknell, Jane, Bruschettini, Matteo, Gautham, Kanekal S,, Pahl, Adrienne,, Soll, Roger F,, Borys, Franciszek,, Bolanos, Luis,, Bruschettini, Matteo,, Lund University.   +14 more
core   +1 more source

A novel translational model for fetoscopic intratracheal delivery of nanoparticles in piglets

, 2016
Objectives The aim of this study was to assess the feasibility of fetal tracheal injection in the late-gestational pig to target the airways. Methods Following laparotomy and hysterotomy, fetoscopy was performed in pregnant sows to access the fetal ...
De Boeck, K, Engels, AC, Bosch, B, M C Mori da Cunha, G M, Deprest, JA, Joyeux, L, Vidovic, D, Carlon, MS, Debyser , Z, Neyrinck, A, Debyser, Zeger, De Boeck, Kris, Joyeux, Luc, Luc Joyeux, Bosch, Barbara, Zeger Debyser, Carlon, Marianne S., Marianne S. Carlon, Neyrinck, Arne, Mori da Cunha, Marina G. M. C., Alexander C. Engels, Dragana Vidović, Arne Neyrinck, Jan A. Deprest, Mori da Cunha, Marina G.MC., Barbara Bosch, Deprest, Jan A., Marina G. M. C. Mori da Cunha, Vidovic, Dragana, Engels, Alexander C., Kris De Boeck   +30 more
core   +1 more source

Acute intratracheal Pseudomonas aeruginosa infection in cystic fibrosis mice is age-independent

Respiratory Research, 2011
Background Since the discovery of the human CFTR gene in 1989 various mouse models for cystic fibrosis (CF) have been generated and used as a very suitable and popular tool to approach research on this life-threatening disease.
Munder Antje, Wölbeling Florian, Kerber-Momot Tanja, Wedekind Dirk, Baumann Ulrich, Gulbins Erich, Tümmler Burkhard   +6 more
doaj   +1 more source

Neutralization of IL‐17A Ameliorates PM2.5‐Induced Cardiac Inflammation and Fibrosis in Rats by Suppressing the TXNIP/NLRP3 Signaling Pathway

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Fine particulate matter (PM2.5) pollution is a major environmental risk factor for cardiovascular diseases. Exposure can cause cardiac inflammation and fibrosis. However, whether interleukin‐17A (IL‐17A) contributes to these effects is unclear.
An‐Shuai Ba, Meng Wu, Wei‐Chen Li, Wei‐Yi Li, Di Ma, Yu Wang, Zhen‐Zhen Chen   +6 more
wiley   +1 more source

Learning curve of nurse‐performed electromagnetic‐guided nasogastric tube placement in adult ICU patients: A multicenter prospective study

Nutrition in Clinical Practice, EarlyView.
Abstract Background Safe and timely nasogastric tube (NGT) placement is essential for effective enteral nutrition delivery in critically ill patients. Electromagnetic‐guided systems has been shown to improve placement accuracy and may reduce delays from confirmatory imaging, but evidence on how nurses acquire competence with this technology remains ...
Kazunao Mori, Hideaki Sakuramoto, Tomoaki Ikezawa, Megumi Kamogawa, Hideaki Note, Toshifumi Miki, Saiko Okamoto, Maiko Motoki, Hideki Hashimoto, Junko Tatsuno, Tomomi Yoshida, Saori Kajiwara, Masako Shirasaka, Megumi Mukouyama, Hitoshi Tsugu, Kensuke Nakamura   +15 more
wiley   +1 more source

Augmentation of Omicron BA.1 pathogenicity in hamsters using intratracheal inoculation

, 2023
The Omicron BA.1 variant of SARS-CoV-2 displays an attenuated phenotype in the Syrian hamster after intranasal inoculation. This is characterized by reduced viral replication and lung pathology in the lower respiratory tract.
Claude Yinda Kwe (9262433), Brian J. Smith (17683674), Carl I. Shaia (704916), Jonathan Schulz (8617601), Vincent Munster (9399053), Julia Port (11021298), Claire Ruckel (17683667)   +6 more
core   +1 more source

Plant‐Derived Extracellular Vesicles: Biogenesis, Function, and Application in Cancer Immunotherapy

Phytotherapy Research, EarlyView.
This illustration shows the biogenesis pathways of edible and medicinal plant‐derived extracellular vesicles (PDEVs) and their therapeutic effects following uptake in the human body, highlighting their potential for application in cancer immunotherapy. ABSTRACT Plant‐derived extracellular vesicles (PDEVs) are nanoscale, lipid bilayer‐enclosed vesicles ...
Guosheng Li, Mengyu Li, Shujing Liu, Yuan Wei, Chen Wang   +4 more
wiley   +1 more source