Results 121 to 130 of about 39,887 (243)
Post Operative Severe Subcutaneous Emphysema
Introduction: Nowadays establishment of a safe and secure airway for general anesthesia is necessary and establishment of the airway , according to the anatomical and physiological state, may be accompanied with complications such as piriform sinus ...
Amir Asadi Fakhr +2 more
doaj
OBJETIVO: Estudar as alterações hemodinâmicas e respiratórias em ratos submetidos ou não ao pneumoperitônio com CO2, sob anestesia com ou sem intubação intratraqueal.
Flávia Coelho de Souza Botter +3 more
doaj +1 more source
This study designs a targeted nanocomposite (ct@HMCF‐Dex) that responds to acidic infection microenvironments, releasing components which amplify oxidative stress. It disrupts bacterial redox balance, chelates metals to sustain lipid peroxidation, and synergistically induces cuproptosis/ferroptosis‐like death.
Zehui Xiao +6 more
wiley +1 more source
Targeted Nanoclusters for Intratracheal Delivery in Intraoperative Imaging of Lung Adenocarcinoma
Lu Tang,1 Ning Li,2 Zhe Yang,3 Yangliu Lin,4 Ge Gao,5 Quan Lin,4 Yue Wang6 1Department of Breast Surgery, China-Japan Union Hospital of Jilin University, Changchun, Jilin, People’s Republic of China; 2Department of Respiratory Medicine, China-Japan Union
Yang Z +6 more
core
Thinned apple polyphenols (TAP) extract reduced ferroptosis in acute and chronic lung injuries. TAP activated Nrf2 and modulated key biomarkers (MDA, NOX4, GPX4, FTH1), leading to decreased inflammation and fibrosis. These findings suggest TAP as a potential therapeutic approach for lung injury through ferroptosis regulation. ABSTRACT Acute and chronic
Rosalba Siracusa +8 more
wiley +1 more source
Background Infection of mice with mouse-adapted strains of influenza virus has been widely used to establish mouse pneumonia models. Intranasal inoculation is the traditional route for constructing an influenza virus-induced pneumonia mouse model, while ...
Hui-Ying Yang +7 more
core +1 more source
ABSTRACT IgA nephropathy (IgAN), the most common form of glomerulonephritis, is a major and growing public health issue. It results from intestinal barrier dysfunction that leads to mesangial deposition of pathogenic galactose‐deficient IgA1 (Gd‐IgA1) and renal inflammation.
Meng‐Si Li, Kai Liu
wiley +1 more source
Repetitive intratracheal bleomycin models several features of idiopathic pulmonary fibrosis
Single-dose intratracheal bleomycin has been instrumental for understanding fibrotic lung remodeling, but fails to recapitulate several features of idiopathic pulmonary fibrosis (IPF).
Vasiliy V. Polosukhin +8 more
core +1 more source
Acute Lung Injury: From Molecular Circuits to System‐Level Therapeutics
This visual summary illustrates the paradigm shift from linear pathways to network medicine in ALI. Three interconnected circuits—innate immunity, immunometabolism, and cell death (PANoptosis)—drive disease progression under multiorgan crosstalk (gut–lung, brain–lung).
Yaoli Hou +10 more
wiley +1 more source
Intratracheal antioxidants attenuate exsanguination-induced bronchoconstriction in guinea pigs
The role of oxygen radicals in exsanguination-induced bronchoconstriction (EIB) was investigated using intratracheal instillation of antioxidants. In series 1, 49 guinea pigs (331 +/- 6 g) were employed in the functional study.
Y. L. Lai, H. Q. Zhang
core +1 more source

