Results 91 to 100 of about 53,430 (234)

Human and bovine respiratory syncytial virus vaccine research and development [PDF]

, 2008
Human (HRSV) and bovine (BRSV) respiratory syncytial viruses (RSV) are two closely related viruses, which are the most important causative agents of respiratory tract infections of young children and calves, respectively.
Deplanche, Martine, Meyer, Gilles, Schelcher, François   +2 more
core   +2 more sources

Chronic, Environmentally Relevant PM2.5 Exposure Exacerbates Metabolic Dysfunction‐Associated Steatotic Liver Disease and Early‐Stage Renal Dysfunction in a Rodent Model

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT While epidemiological studies link fine particulate matter (PM2.5) exposure to metabolic dysfunction‐associated steatotic liver disease (MASLD) and renal dysfunction, a translational gap exists, as most animal models utilize acute, high‐dose exposures that poorly reflect chronic, moderate‐level human scenarios.
Yi‐Siao Chen, Hugo You‐Hsien Lin, Chien‐Tzu Lin, Si‐Hua Huang, Ming‐Lun Yeh, Ming‐Lung Yu, Jin‐Ching Lee, Yao‐Chi Chung, Wei‐Ming Li, Ching‐Chia Li, Shiu‐Feng Huang, Chia‐Hung Yen   +11 more
wiley   +1 more source

Toxicity of lunar dust

, 2012
The formation, composition and physical properties of lunar dust are incompletely characterised with regard to human health. While the physical and chemical determinants of dust toxicity for materials such as asbestos, quartz, volcanic ashes and urban ...
Alving, Asano, Basu, Bice Fubini, Bosquillon, Brain, Brown, Brunetto, Butler, Cain, Cain, Castranova, Castranova, Christoffersen, Dag Linnarsson, Damm, Darquenne, Darquenne, Darquenne, Darquenne, Darquenne, David J. Loftus, Dockery, Driscoll, Erin M. Tranfield, Ewing, Fanizza, Fenoglio, Fenoglio, Fenoglio, Fenoglio, Frampton, Fubini, Fubini, Fubini, Fubini, Fubini, Fubini, Fubini, Fubini, Fujishima, G. Kim Prisk, Gaier, Geiser, Gerde, Gerde, Ghiazza, Gustafsson, Hardy, Hardy, Harmsen, Heinrich, Hemmingsson, Heyder, Hill, Hong, Horanyi, Horwell, Horwell, Hurowitz, Ialenti, Ignarro, James, James, James Carpenter, Jones, Kamp, Kane, Karlsson, Khan-Mayberry, Kharitonov, Kharitonov, Kobrick, Lam, Lane, Lars L. Karlsson, Larsen, Latch, Lison, Lison, Liu, Liu, Loftus, Lucey, Lundberg, Lynch, MacLoughlin, McClellan, McKay, McKay, Moller, Mossman, Nel, Nel, Nemmar, Nikula, Norde, Oberdörster, Oberdörster, Oberdörster, Oberdörster, Park, Parsegian, Patil, Pauluhn, Pauluhn, Pawloski, Per Gerde, Persson, Peters, Peters, Peters, Peterson, Pezerat, Pope, Pope, Popov, Porter, Rask, Ricciardolo, Saffiotti, Sahai, Sakagami, Sakagami, Samet, Sanchez, Santana, Scheuch, Schwartz, Seagrave, Seaton, Seaton, Selg, Semmler, Shukla, Smaldone, Stahlhofen, Stanton, Sundblad, Taylor, Taylor, Taylor, Taylor, Thompson, Tranfield, Tronde, Tsuda, Turci, Turci, Urs Staufer, Vallyathan, van Eeden, von Klot, Wallace, Warheit, Warheit, West, Wim van Westrenen, Wong, Zanobetti   +159 more
core   +1 more source

Triggering Receptor Expressed on Myeloid Cells‐2 Regulates Innate Lymphoid Cell Levels in Bleomycin‐Induced Pulmonary Fibrosis

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Idiopathic pulmonary fibrosis, a pathological change causing poor outcomes, is not reversible despite current antifibrotic therapy. Emerging evidence suggests that innate lymphoid cells (ILCs) mediate lung inflammation and fibrosis after stimulation by endogenous factors.
Hsiao‐Chin Shen, Nien‐Jung Chen, Chuan‐Yen Sun, Wen‐Kuang Yu, Vincent Yi‐Fong Su, Wan‐Ling Yang, Wei‐Chih Chen, Kuang‐Yao Yang   +7 more
wiley   +1 more source

Ninjurin 1 contributes to TLR-induced inflammation in endothelial cells [PDF]

, 2012
Background: Nerve injury induced protein 1 (Ninjurin 1 (Ninj1)) was first identified in Schwann cells and neurons contributing to cell adhesion and nerve regeneration.
Jennewein, Carla, Zacharowski, Kai
core   +1 more source

Effects of Mesenchymal Stem Cell‐Derived Exosomes on Lung Inflammation in a Murine Aspiration Model

The Laryngoscope, EarlyView.
This study assessed the effect of intravenous MSC‐derived exosomes on inflammatory lung injury in a rat model of LPS aspiration. Compared with LPS alone, MSC exosome treatment reduced histologic lung injury overall (significant group effect p = 0.02; linear trend p = 0.006) and significantly lowered Tnf gene expression on qRT‐PCR (p < 0.05).
Nogah Nativ‐Zeltzer, Rumi Ueha, Johnathon D. Anderson, Yuval Nachalon, Denise M. Imai, Peter C. Belafsky   +5 more
wiley   +1 more source

Acute intratracheal Pseudomonas aeruginosa infection in cystic fibrosis mice is age-independent

Respiratory Research, 2011
Background Since the discovery of the human CFTR gene in 1989 various mouse models for cystic fibrosis (CF) have been generated and used as a very suitable and popular tool to approach research on this life-threatening disease.
Munder Antje, Wölbeling Florian, Kerber-Momot Tanja, Wedekind Dirk, Baumann Ulrich, Gulbins Erich, Tümmler Burkhard   +6 more
doaj   +1 more source

IKKα inactivation promotes Kras-initiated lung adenocarcinoma development through disrupting major redox regulatory pathways. [PDF]

, 2018
Lung adenocarcinoma (ADC) and squamous cell carcinoma (SCC) are two distinct and predominant types of human lung cancer. IκB kinase α (IKKα) has been shown to suppress lung SCC development, but its role in ADC is unknown.
Hu, Yinling, Johnson, Peter F, Karin, Michael, Ma, Buyong, Nussinov, Ruth, Schrump, David S, Song, Na-Young, Su, Ling, Sun, Zhonghe, Wang, Zining, Willette-Brown, Jami, Wu, Xiaolin, Xi, Sichuan, Xia, Xiaojun, Zhu, Feng   +14 more
core   +1 more source

Acute inflammatory response to contrast agent aspiration and its mechanisms in the rat lung. [PDF]

, 2019
Objectives/hypothesisContrast agent (CA) aspiration is an established complication of upper gastrointestinal and videofluoroscopic swallow studies. The underlying molecular biological mechanisms of acute response to CA aspiration in the respiratory ...
Belafsky, Peter C, Goto, Takao, Nativ-Zeltzer, Nogah, Nito, Takaharu, Sato, Taku, Ueha, Rumi, Yamasoba, Tatsuya   +6 more
core   +1 more source

Migrasomes, Matrix‐Bound Nanovesicles, and More: Messengers in the Matrix

PROTEOMICS, EarlyView.
ABSTRACT Extracellular vesicles (EVs) and particles (EPs) are diverse micro‐ and nanoparticles that circulate in bodily fluids and can attach to, or be deposited onto, the extracellular matrix (ECM) and other surfaces. To date, the nomenclature and classification of matrix‐bound or matrix‐associated EVs and EPs (MEVPs) have been unclear, largely due to
Anna V. Kolesov, Natalie Reitz, Marley Dewey, Colin L. Hisey   +3 more
wiley   +1 more source