Results 91 to 100 of about 43,236 (245)

Intratracheal Administration of Itraconazole-Loaded Hyaluronated Glycerosomes as a Promising Nanoplatform for the Treatment of Lung Cancer: Formulation, Physiochemical, and In Vivo Distribution

Pharmaceutics
Background: Itraconazole (ITZ) is an antiangiogenic agent recognized as a potent suppressor of endothelial cell growth that suppresses angiogenesis. Nevertheless, its exploitation is significantly restricted by its low bioavailability and systematic side
Sultan Aati, Hanan O. Farouk, Marwa H. Elkarmalawy, Hanan Y. Aati, Nahla Sameh Tolba, Hossam M. Hassan, Mostafa E. Rateb, Doaa S. Hamad   +7 more
doaj   +1 more source

Oral Endotracheal Intubation with Restricted Glottis View using C-MAC D Blade®: A Randomised Controlled Trial [PDF]

Journal of Clinical and Diagnostic Research
Introduction: The perspective of airway management has undergone a considerable transformation since the advent of Video Laryngoscopes (VL). VL has rapidly been accepted as an intubation tool in a variety of clinical scenarios.
Vaidarbhi Rasikbhai Patel, Nirali Nimeshkumar Panchal, Sanket Hirenbhai Mehta, Madhavi Sanjay Chaudhari, Bhumika Pradipkumar Pathak, Mayur Kiran shinde   +5 more
doaj   +1 more source

The Nuclear Receptor Testicular Receptor 4 Orchestrates Cytoskeletal Organization in a G Protein Subunit Alpha 12/Rho‐Associated Protein Kinase–Dependent Manner to Promote Myofibroblast Differentiation and Tissue Fibrosis in Systemic Sclerosis

Arthritis &Rheumatology, EarlyView.
Objective Members of the superfamily of nuclear receptors have been implicated in inflammatory processes and pathologic tissue remodeling and have emerged as attractive targets for pharmaceutical intervention. However, the role of testicular receptor 4 (TR4; or Nr2c2) in fibroblast activation and rheumatologic diseases has not yet been investigated ...
Yun Zhang, Lichong Shen, Junhui Zheng, Gisela Baur, Dilidaer Yasen, Honglin Zhu, Yi‐Nan Li, Xianyi Meng, Thuong Trinh‐Minh, Tim Filla, Debomita Chakraborty, Andrea‐Hermina Györfi, Christina Bergmann, Adam Reich, Alexander Kreuter, Georg Schett, Jörg H. W. Distler   +16 more
wiley   +1 more source

Intratracheal transplantation of endothelial progenitor cells attenuates smoking-induced COPD in mice

, 2017
Zhihui Shi,1 Yan Chen,1 Jun Cao,2 Huihui Zeng,1 Yue Yang,1 Ping Chen,1 Hong Luo,1 Hong Peng,1 Shan Cai,1 Chaxiang Guan3 1Department of Internal Medicine, Division of Respiratory Disease, The Second Xiangya Hospital, Central-South University, 2Department
Peng H, Yang Y, Chen P, Cai S, Cao J, Guan C, Chen Y, Zeng H, Luo H, Shi Z   +9 more
core  

Intratracheal instillation of a novel NO/nucleophile adduct selectively reduces pulmonary hypertension

, 1997
Brilli, Richard J., Brian Krafte-Jacobs, Daniel J. Smith, Dominick Roselle, Daniel Passerini, Amos Vromen, Lori Moore, Csaba Szabó, and Andrew L. Salzman.
Richard J. Brilli, Lori Moore, Csaba Szabó, Dominick Roselle, Brian Krafte-Jacobs, Daniel Passerini, Andrew L. Salzman, Daniel J. Smith, Amos Vromen   +8 more
core   +1 more source

The synergistic impact of granulocytic myeloid‐derived suppressor cells and innate lymphoid cells in systemic sclerosis

Arthritis &Rheumatology, Accepted Article.
Objective Systemic sclerosis (SSc) is a chronic autoimmune disorder characterized by immune dysregulation and fibrosis, with myeloid‐derived suppressor cells (MDSCs) emerging as important regulators of immune responses. However, the role of MDSCs in SSc‐associated fibrosis and their interactions with other immune cell populations remain poorly ...
Stefanie Weber, Mario R. Angeli, Hashem Mohammadian, Hannah Labinsky, Maria Gabriella Raimondo, Richard Demmler, Yuko Ariza, Thomas Wohlfahrt, Markus Luber, Yi‐Nan Li, Jörg H.W. Distler, Tobias Bäuerle, Georg Schett, Simon Rauber, Andreas Ramming, Alina M. Ramming   +15 more
wiley   +1 more source

Electron compensation‐gated nanomotor for immunomodulation and microenvironment remodeling in bacterial pneumonia therapy

BMEMat, EarlyView.
A nanomotor featuring an “electronic lock” via electron compensation in an Au‐Ag alloy ensures therapeutic precision. Near‐infrared light acts as a key, unlocking on‐demand Ag+ release for synergistic bactericidal action and microenvironment remodeling to potently treat bacterial pneumonia. Abstract Bacterial pneumonia treatment is severely hampered by
Chenglong Xue, Xiaoyu Zhao, Yuqian Wang, Lijin Shi, Qi Shuai   +4 more
wiley   +1 more source

Navigating One-lung Ventilation after Lobectomy: Anesthetic Challenges in Physiological Lung Exclusion

Medical Journal of Dr. D.Y. Patil Vidyapeeth
Management of one-lung ventilation in patients undergoing repeat thoracic surgery presents unique challenges, particularly with an existing bronchopleural fistula and a history of lobectomy. Here we discuss a case of a 46-year-old woman with a history of
Subhashree Jena, Shahbaz Hasnain, Brinda Badam   +2 more
doaj   +1 more source

Autonomous Nanomedicine: Closing the Biological Validation Gap

Exploration, EarlyView.
Delivery of nanoparticles to tumors has not improved in over fifteen years, and biological testing remains slow and separate from formulation design. This review proposes adding a Biology step to the design cycle, using organ chips and patient‐derived organoids, and assesses the readiness of each required technology.
Yan Jun Lin, Izabella Komperda
wiley   +1 more source

Targeted Nanoclusters for Intratracheal Delivery in Intraoperative Imaging of Lung Adenocarcinoma [PDF]

Lu Tang,1 Ning Li,2 Zhe Yang,3 Yangliu Lin,4 Ge Gao,5 Quan Lin,4 Yue Wang6 1Department of Breast Surgery, China-Japan Union Hospital of Jilin University, Changchun, Jilin, People’s Republic of China; 2Department of Respiratory Medicine, China-Japan Union
Yang Z, Lin Q, Tang L, Lin Y, Gao G, Wang Y, Li N   +6 more
core