Results 71 to 80 of about 9,756 (290)

Intratympanic dexamethasone for managing pregnant women with sudden hearing loss

Journal of International Medical Research, 2019
Objective This study aimed to investigate the effect and safety of intratympanic dexamethasone in pregnant women with idiopathic sudden sensorineural hearing loss (ISSNHL).
Yaoyao Fu, Jianghua Jing, Tongli Ren, Hui Zhao   +3 more
doaj   +1 more source

Local Delivery of Therapeutics to the Inner Ear: The State of the Science

Frontiers in Cellular Neuroscience, 2019
Background: Advances in the understanding of the genetic and molecular etiologies of inner ear disorders have enabled the identification of therapeutic targets and innovative delivery approaches to the inner ear.
Caroline R. Anderson, Caroline R. Anderson, Carol Xie, Carol Xie, Matthew P. Su, Matthew P. Su, Maria Garcia, Maria Garcia, Helen Blackshaw, Helen Blackshaw, Anne G. M. Schilder, Anne G. M. Schilder   +11 more
doaj   +1 more source

Efficacy and Durability of Intratympanic Gentamicin Treatment for Meniere's Disease

Frontiers in Neurology, 2021
Objective: To study the success of intratympanic gentamicin (ITG) treatment in reducing vertigo attacks in Meniere's disease (MD) and the value of the Halmagyi head thrust test (HTT) in predicting treatment durability.
Yafeng Guan, D. Chari, Yu-Hsi Liu, S. Rauch   +3 more
semanticscholar   +1 more source

Adjunctive Hyperbaric Oxygen Therapy or Intratympanic Steroids in Sudden Sensorineural Hearing Loss?

The Laryngoscope, EarlyView.
Sudden sensorineural hearing loss is traditionally treated with steroids, either orally and/or via intratympanic injections, and hyperbaric oxygen treatment (HBOT) has resurged in popularity as an adjunctive therapy. The study has not found any additional treatment benefit with adjunctive concurrent HBOT; however, HBOT might be of value to patients ...
Jennifer L. Spiegel, Michael J. De Biasio, Gianluca Sampieri, Omer J. Ungar, Munir D. Bajin, Vincent Y. W. Lin, Joseph M. Chen, Chris Idestrup, Jordan Tarshis, Trung N. Le   +9 more
wiley   +1 more source

Mesna in Otologic Surgery: Efficacy and Safety—A Scoping Review

The Laryngoscope, EarlyView.
PRISMA flow diagram indicating the process of systematic inclusion and exclusion of articles. ABSTRACT Objective Mesna (Sodium 2‐mercaptoethanesulfonate) is widely used as a mucolytic agent and uroprotective agent. Recently, its disulfide bond‐breaking property has been applied in otologic surgery to facilitate safer dissection of cholesteatoma and ...
Kevork H. Atamian, Inabat Yermesheva, Ostap Orishchak, Hady Tall, Sam J. Daniel   +4 more
wiley   +1 more source

The Current Situation and Development of Endoscopic Ear Surgery in China

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Endoscopic ear surgery has been widely performed in China since 2015 due to the development and rapid popularization of endoscopic technology. Due to the relative shortness of the auditory meatus, only a fixed endoscope is required in many cases, rather than a motion similar to a nasal endoscope, and uncontrollable bleeding is virtually non ...
Meng‐Wen Shi, Ge Yin, Yu Sun
wiley   +1 more source

Factors Affecting Intratympanic Corticosteroids Injection Therapy Results in Sudden Deafness Patients at Dr Mohammad Hoesin Hospital Palembang

Bioscientia Medicina : Journal of Biomedicine and Translational Research, 2021
Background. Sudden deafness is an emergency in the Ear Nose Throat Department, a subset of sensorineural hearing loss within a 72-hour window period and consists of a decrease in hearing of 30 decibels affecting at least three consecutive frequencies ...
Abla Ghanie, Listya Paramita, Fiona Widyasari, Ahmad Hifni, Erial Bahar   +4 more
semanticscholar   +1 more source

Sudden Sensorineural Hearing Loss: Results of intratympanic steroids as salvage treatment [PDF]

, 2013
Objective: The aim of the present study was to verify the efficacy and the safety of intratympanic dexamethasone to treat sudden sensorineural hearing loss as salvage therapy. Materials and methods: A prospective study was conducted on patients affected
COSTANTINO, Claudio, De Stefano, A, DISPENZA, Francesco, MARCHESE, Donatella, Riggio, F.   +4 more
core   +1 more source

Intratympanic aberrant and hypoplastic carotid artery

American Journal of Otolaryngology, 2013
Intratympanically aberrant internal carotid artery(ICA) is a rarely seen vascular abnormality. We present here the combination of aberration and prominent hypoplasia of the ICA in a case. Intratympanic aberrant ICA, which is rarely cited as a cause of tinnitus and hearing loss, should be known as a reason to be kept in mind as it may lead to life ...
TUGRUL, Selahattin, Eren, SABRİ BAKİ, Dogan, REMZİ, KOCAK, Ilker, Sharifov, RASUL, Ozturan, ORHAN   +5 more
openaire   +3 more sources

Delivery strategies of messenger RNA therapeutics for brain disorders

Bulletin of the Korean Chemical Society, Volume 46, Issue 12, Page 1186-1204, December 2025.
Thus, mRNA therapeutics offer a powerful new avenue for the treatment of brain diseases. This review examines strategies to bypass biological barriers, particularly the blood–brain barrier, and explores emerging delivery systems, such as direct intracerebral injection, intracerebroventricular injection, systemic delivery (including intravenous ...
Kounghwa Youn, Sunmin Oh, Hyunchae Gil, Yongseok Choi, Gyochang Keum, Eun‐Kyoung Bang   +5 more
wiley   +1 more source