Results 51 to 60 of about 4,501 (207)

The Relationship Between Blood Lipids, Coagulation Indexes, Blood Homocysteine and Sudden Deafness: A Retrospective Study and Mendelian Randomization Analysis

open access: yesWorld Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Background Certain blood components, including blood lipids, coagulation parameters, and homocysteine, have been suggested to correlate with the incidence and prognosis of sudden sensorineural hearing loss (SSNHL). However, the nature of these associations remains controversial.
Feng‐Xin Yang   +8 more
wiley   +1 more source

Dexamethasone does not affect endolymphatic hydrops (EH) in patients with Meniere's disease within 24 h, and intratympanic administration of gadolinium plus dexamethasone simplifies high-quality imaging of EH using a novel protocol of 7 min

open access: yesJournal of Otology, 2022
Background: Intratympanic administration of gadolinium chelate allows for a better visualization of endolymphatic hydrops (EH) using MRI than intravenous injection and was recently further improved to facilitate high-quality imaging of EH in 7 min.
Jing Zou   +6 more
doaj   +1 more source

Characterization of the Middle Ear Microbiome in Meniere's Disease by 16S rRNA Gene Sequencing Compared to Chronic Suppurative Otitis Media

open access: yesWorld Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Objective To investigate the middle ear microbiome in Meniere's disease (MD) patients. Methods Middle ear smears from 10 MD patients (ME group) and 10 chronic suppurative otitis patients (OE group) were collected during surgery and processed via 16S rRNA gene sequencing.
Yu‐Ting Tao   +3 more
wiley   +1 more source

Landmark‐Based Anatomical Dissection and Real‐Time Functional Assessment of the Mouse Eustachian Tube

open access: yesLaryngoscope Investigative Otolaryngology, Volume 11, Issue 6, December 2026.
ABSTRACT Objective Eustachian tube dysfunction (ETD) contributes to middle ear diseases, but practical methods for functional assessment in mice remain limited. We aimed to develop a landmark‐guided mouse Eustachian tube (ET) dissection protocol and a real‐time pressure‐based system for ET functional evaluation. Methods A detachable portable device was
Xuan Yu   +6 more
wiley   +1 more source

The cochlear morphometry compendium: High‐resolution synchrotron measurements and normative reference values

open access: yesJournal of Anatomy, Volume 249, Issue 6, Page 1290-1308, December 2026.
In this study, 100 cadaveric temporal bones underwent synchrotron radiation phase‐contrast imaging. Images were segmented to produce 3D surface mesh models for morphological analysis. Measurements obtained for all cochleae included: standard gross dimensions, various cochlear lengths including basilar membrane length, detailed intracochlear scalar ...
Sumit K. Agrawal   +4 more
wiley   +1 more source

Emerging biological therapy vs. conventional steroid treatment in unilateral sudden sensorineural hearing loss (SSNHL) : a comparative study

open access: yesThe Egyptian Journal of Otolaryngology
Background Sudden sensorineural hearing loss (SSNHL) is an otologic emergency commonly treated with corticosteroids; however, hearing recovery remains variable.
Kirtika Gupta   +6 more
doaj   +1 more source

Nanoporous Silica Embedded in Nanoporous Platinum: A Versatile Composite Coating for Implant‐Associated Drug Delivery From Neuronal Electrodes

open access: yesAdvanced Materials Technologies, Volume 11, Issue 19, 7 October 2026.
Nanoporous silica nanoparticles incorporated in nanoporous platinum offer the possibility for implant‐associated drug delivery from neuronal electrodes. ABSTRACT Sensorineural hearing loss, resulting from damage to the hair cells of the inner ear, profoundly impairs quality of life.
Mosaieb Habib   +10 more
wiley   +1 more source

Otogenic Sigmoid Sinus Thrombosis Complicated by Cerebellar Abscess and Hydrocephalus: A Case Report

open access: yesClinical Case Reports, Volume 14, Issue 10, October 2026.
ABSTRACT A 44‐year‐old man developed otogenic sigmoid sinus thrombosis with cerebellar abscess, hydrocephalus, and recurrent posterior fossa infection. Staged neurosurgical drainage and canal‐wall‐down mastoidectomy achieved source control. Cultures were negative. Anticoagulant exposure was perioperative/early postoperative.
Alexandra Mădălina Bizdu‐Branovici   +6 more
wiley   +1 more source

Poly-Lactic Acid-Based Biopolymer Formulations Are Safe for Sustained Intratympanic Dexamethasone Delivery

open access: yes, 2019
The clinical treatment of sudden sensorineural hearing loss currently relies on the administration of steroids, either systemically or via intratympanic injections.
Senn, Pascal   +26 more
core   +1 more source

Cochlear Implantation in Myelin Oligodendrocyte Glycoprotein Antibody‐Associated Disease

open access: yesClinical Case Reports, Volume 14, Issue 10, October 2026.
ABSTRACT Myelin oligodendrocyte glycoprotein antibody‐associated disease (MOGAD) is a neuroimmunologic demyelinating disorder that may present with central or peripheral sensorineural hearing loss (SNHL). This case describes a 43‐year‐old female with MOGAD and profound right‐sided SNHL who did not improve with neuroimmunologic therapy.
Jacob Mabey   +2 more
wiley   +1 more source

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