Results 41 to 50 of about 4,501 (207)

Impact of Age and Nerve Impairment Interaction on Bell's Palsy Prognosis

The Laryngoscope, EarlyView.
This study investigated the prognostic impact of the interaction between aging and nerve impairment severity in 181 patients with Bell's palsy. Although age alone was not an independent predictor, the interaction between older age (≥ 65 years) and a Nerve Excitability Test threshold difference (≥ 3.5 mA) significantly increased the risk of incomplete ...
Hiroyuki Yamada, Miyuki Oshita, Takemichi Tanaka, Shota Miyaji, Takuya Kimura, Shinji Iwata, Ryota Takagi, Naohito Hato   +7 more
wiley   +1 more source

Idiopathic sudden sensorineural hearing loss: Effectiveness of salvage treatment with low-dose intratympanic dexamethasone

Journal of Otology, 2021
Objectives: To evaluate hearing outcome of salvage treatment with intratympanic steroids (ITS) in idiopathic sudden sensorineural hearing loss (ISSNHL) refractory to initial systemic steroid (SS) therapy.
Pedro Salvador, Francisco Moreira da Silva, Rui Fonseca   +2 more
doaj   +1 more source

Intratympanic membrane cholesteatoma after traumatic tympanic membrane perforation: a case report

Journal of Medical Case Reports, 2023
Background Intratympanic membrane cholesteatoma presents as an asymptomatic, white, round mass on the tympanic membrane, and is usually detected incidentally in children.
Junhui Jeong, Hyun Seung Choi
doaj   +1 more source

Small Molecule Therapeutic Approaches With a Greater Focus on Hearing Loss: A Review [PDF]

Health Sci Rep
ABSTRACT Background and Aims Hearing loss (HL) is one of the most common sensory impairments worldwide and has substantial effects on quality of life and daily functioning. Although cochlear implants and hearing aids have markedly improved the management of hearing impairment, these devices do not directly address the underlying pathogenic mechanisms ...
Naghinejad M, Motallebi F, Hasani E, Kohkalani M, Parvizpour S, Mansoori Derakhshan S.   +5 more
europepmc   +2 more sources

Efficacy of Intratympanic Sodium Thiosulfate Gel Injection to Prevent Cisplatin‐Induced Ototoxicity

The Laryngoscope, EarlyView.
This randomized controlled trial included 28 patients with head and neck cancer receiving cisplatin chemotherapy, with intratympanic sodium thiosulfate gel administered to one ear and the contralateral ear serving as control. Based on ASHA criteria, the incidence of ototoxicity did not differ significantly between treated and control ears.
Kunyakorn Vittayakoonsakulchai, Pittayapon Pitathawatchai, Yuvatiya Plodpai, Viraporn Atchariyasathian, Wandee Khaimook, Virat Kirtsreesakul, Rungarun Kittichet, Pattarawadee Prayuenyong   +7 more
wiley   +1 more source

Inner Ear Therapeutics: An Overview of Middle Ear Delivery

Frontiers in Cellular Neuroscience, 2019
There are a variety of methods to access the inner ear and many of these methods depend on utilizing the middle ear as a portal. In this approach the middle ear can be used as a passive receptacle, as part of an active drug delivery system, or simply as ...
Jaimin Patel, Mikhaylo Szczupak, Suhrud Rajguru, Suhrud Rajguru, Carey Balaban, Michael E. Hoffer, Michael E. Hoffer   +6 more
doaj   +1 more source

Molecular Biomarkers in Meniere's Disease: A Scoping Review of Current Evidence

Otolaryngology–Head and Neck Surgery, EarlyView.
Abstract Objective Meniere's disease is a complex chronic inner ear condition that is characterized by vertigo, tinnitus, aural fullness, and progressive hearing loss. Currently, diagnostic strategies remain symptom‐driven, and treatments focus on management of discrete episodes rather than targeting underlying pathophysiology.
Hamza Kamran, Zaharadeen Jimoh, Tariq Issa, Nahla A. Gomaa   +3 more
wiley   +1 more source

Local Delivery of Therapeutics to the Inner Ear: The State of the Science

Frontiers in Cellular Neuroscience, 2019
Background: Advances in the understanding of the genetic and molecular etiologies of inner ear disorders have enabled the identification of therapeutic targets and innovative delivery approaches to the inner ear.
Caroline R. Anderson, Caroline R. Anderson, Carol Xie, Carol Xie, Matthew P. Su, Matthew P. Su, Maria Garcia, Maria Garcia, Helen Blackshaw, Helen Blackshaw, Anne G. M. Schilder, Anne G. M. Schilder   +11 more
doaj   +1 more source

Optimizing Hyperbaric Oxygen Therapy for Sudden Hearing Loss

Otolaryngology–Head and Neck Surgery, EarlyView.
Abstract Objective To optimize the hyperbaric oxygen therapy protocol for sudden sensorineural hearing loss by identifying the most effective treatment course and analyzing key prognostic factors through a multicenter retrospective cohort study. Study Design Retrospective cohort study.
Yuting Sun, Yu Yang, Zhentao Wang, Hui Zhao, Xiaoli Ge, Shuming Pan   +5 more
wiley   +1 more source

Sudden hearing loss: an effectivity comparison of intratympanic and systemic steroid treatments

, 2017
Corticosteroid treatment has been considered the most effective treatment modality for sudden sensorineural hearing loss so far. Application route of corticosteroids may vary.
Ermutlu, Gulce, Yılmaz, Taner, Nilda Süslü, Sütay Süslü, Nilda, Gülce Ermutlu, Sarac, Sarp, Taner Yılmaz, Sarp Saraç   +7 more
core   +1 more source