Flagellins as Vaccine Adjuvants and Cancer Immunotherapy: Recent Advances and Future Prospects
Immunology, Volume 176, Issue 3, Page 277-303, November 2025.The figure depicts the role of flagellin in immune cells. Flagellin interacts with TLR5, resulting in the formation of homodimers and the recruitment of MyD88, which activates the IκB and MAPK signalling pathways. This results in the activation of NF‐κB and AP‐1, producing TNF‐α, IL‐6, IL‐8, and IL‐12.
Asma Talukder +4 more
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Effect of Repeated Administration of hCG on Ovarian Response in PMSG-superovulated Ouled Djellal Ewes (Algeria) [PDF]
, 2014 The objective of this study was to evaluate the effect of repeated administration of hCG on ovarian response in PMSG-superovulated ewes. Intravaginal pessaries containing 40 mg fluorogestone acetate (FGA) were inserted in all ewes (n=9) and remained in ...
Afri-Bouzebda, F. +4 more
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European Journal of Immunology, Volume 55, Issue 10, October 2025.Th17 cells confer protection against Candida albicans infection. In patients with STAT1 gain‐of‐function (GOF) mutations and chronic mucocutaneous candidiasis (CMC), Candida‐specific Th cell responses are numerically preserved but skewed toward Th1 and Th2.
Camilla Basso +13 more
wiley +1 more source
A vaccine formulated with the major outer membrane protein can protect C3H/HeN, a highly susceptible strain of mice, from a Chlamydia muridarum genital challenge. [PDF]
, 2015 C3H/HeN female mice were vaccinated with native Chlamydia muridarum major outer membrane protein (MOMP), using Montanide+CpG or Alum+CpG as adjuvants. Negative control groups were immunized with ovalbumin (OVA) and the same adjuvants. As positive control,
de la Maza, Luis M +2 more
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Topical fenticonazole in dermatology and gynaecology. current role in therapy
Репродуктивная эндокринология, 2019 The objective of this review is to present the current clinical data on the use of fenticonazole, including data on its efficacy in mixed infections, and to discuss the clinical role of fenticonazole in dermatological and gynaecological indications ...
Стефано Веральді +1 more
doaj +1 more source
Local Salmonella immunostimulation recruits vaccine-specific CD8 T cells and increases regression of bladder tumor. [PDF]
, 2015 The efficacy of antitumoral responses can be increased using combinatorial vaccine strategies. We recently showed that vaccination could be optimized by local administration of diverse molecular or bacterial agents to target and augment antitumoral CD8 T
Chevalier, M.F. +7 more
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A neonatal and maternal death following the administration of intravaginal prostaglandin
Journal of Obstetrics and Gynaecology, 1987 (1987). A neonatal and maternal death following the administration of intravaginal prostaglandin. Journal of Obstetrics and Gynaecology: Vol. 7, No. 4, pp. 271-272.
J. Stronge, J. Monaghan, P. Lenehan
openaire +1 more source
Polymeric gels for intravaginal drug delivery [PDF]
, 2017 This document is the Accepted Manuscript version of the following article: Michael T. Cook, and Marc b. Brown, ‘Polymeric gels for intravaginal drug delivery’, Journal of Controlled Release, Vol. 270: 145-157, January 2018. Under embargo until 6 December
Brown, Marc, Cook, Michael
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Maternal and neonatal outcome of labour induction at term comparing two regimens of misoprostol [PDF]
, 2017 Aim: To compare the efficacy and safety of two misoprostol dosing regimens for induction of labour in primiparous (1P) and multiparous (>1P) women. Methods: Retrospective study of induction of labour using vaginal misoprostol 25 μg vs. 50 μg every 6 h in
Kreft, Martina +5 more
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