Results 31 to 40 of about 2,079,858 (263)
Sexual Medicine, 2023 Background Prasterone, an intravaginal dyspareunia treatment in menopausal women, improves vaginal health through intracellular conversion of dehydroepiandrosterone into androgens and estrogens.
S. Goldstein, I. Goldstein, Noel N Kim
semanticscholar +1 more source
Lactoferrin. A natural glycoprotein involved in iron and inflammatory homeostasis [PDF]
, 2017 Human lactoferrin (hLf), an iron-binding multifunctional cationic glycoprotein secreted by exocrine glands and by neutrophils, is a key element of host defenses.
Cutone, Antimo +4 more
core +2 more sources
Evaluation of TLR agonists as potential mucosal adjuvants for HIV gp140 and tetanus toxoid in mice. [PDF]
PLoS ONE, 2012 In the present study we investigate the impact of a range of TLR ligands and chitosan as potential adjuvants for different routes of mucosal immunisation (sublingual (SL), intranasal (IN), intravaginal (IVag) and a parenteral route (subcutaneous (SC)) in
Viviana Buffa +3 more
doaj +1 more source
Medicina, 2023 Background and Objectives: Preterm birth (PTB) is associated with important neonatal mortality and morbidity. The aim of this study was to retrospectively evaluate the average treatment effects on the treated and the efficacity of various therapeutic ...
Alina-Madalina Luca +12 more
doaj +1 more source
The role of diallyl thiosulfinate associated with nuciferine and diosgenin in the treatment of premature ejaculation: a pilot study [PDF]
, 2018 Objective: To assess the efficacy and safety of an association of diallyl thiosulfinate with nuciferine and diosgenin in the treatment of a group of patients suffering from premature ejaculation (PE), primary or secondary to erectile dysfunction (ED ...
Cai, Tommaso +10 more
core +2 more sources
Journal of Acquired Immune Deficiency Syndromes, 2021 Supplemental Digital Content is Available in the Text. Objective: To describe and compare systemic and local pharmacokinetics (PK) and cervicovaginal (CV) pharmacodynamics (PD) of oral tenofovir disoproxil fumarate (TDF) in combination with emtricitabine
L. Ouattara +10 more
semanticscholar +1 more source
Rationale and safety assessment of a novel intravaginal drug-delivery system with sustained DL-lactic acid release, intended for long-term protection of the vaginal microbiome [PDF]
, 2016 Bacterial vaginosis is a prevalent state of dysbiosis of the vaginal microbiota with wide-ranging impact on human reproductive health. Based on recent insights in community ecology of the vaginal microbiome, we hypothesize that sustained vaginal DL ...
Remon, Jean Paul +2 more
core +4 more sources
Interferon lambda protects the female reproductive tract against Zika virus infection [PDF]
, 2019 Zika virus infections can cause devastating congenital birth defects but the underlying interactions with the host immune system are not well understood.
Arora, Nitin +7 more
core +3 more sources
Novel in situ gelling vaginal sponges of sildenafil citrate-based cubosomes for uterine targeting
Drug Delivery, 2018 Sildenafil citrate (SIL), a type 5-specific phosphodiesterase inhibitor, demonstrates valuable results in the management of infertility in women; however, the absence of vaginal dosage form in addition to the associated oral adverse effects minimize its ...
Heba M. Aboud +3 more
doaj +1 more source
Menopause Review, 2019 The climacteric is considered a natural phase in a woman’s aging process and is defined as the period starting from the decline in ovarian activity until after the end of ovarian function. Genitourinary syndrome of menopause (GSM) is commonly observed in
Valentina Lucia La Rosa +8 more
doaj +1 more source