Results 21 to 30 of about 1,789,709 (166)

Low Immunogenicity of Intravesical Phage Therapy for Urogenitary Tract Infections

Antibiotics, 2021
Patients with chronic urinary and urogenital multidrug resistant bacterial infections received phage therapy (PT) using intravesical or intravesical and intravaginal phage administration.
Sławomir Letkiewicz, Marzanna Łusiak-Szelachowska, Ryszard Międzybrodzki, Maciej Żaczek, Beata Weber-Dąbrowska, Andrzej Górski   +5 more
doaj   +1 more source

Enhanced Delivery of Imatinib into Vaginal Mucosa via a New Positively Charged Nanocrystal-Loaded in Situ Hydrogel Formulation for Treatment of Cervical Cancer

Pharmaceutics, 2019
The present study was carried out to investigate the potential of cationic functionalization on imatinib nanocrystals to improve the mucoadhesiveness and, thus, delivery to the lesion of cervicovaginal tumors.
Li-qian Ci, Zhi-gang Huang, Feng-mei Lv, Jun Wang, Ling-lin Feng, Feng Sun, Shui-juan Cao, Zhe-peng Liu, Yu Liu, Gang Wei, Wei-yue Lu   +10 more
doaj   +1 more source

Influence of administration of Staphylococcus aureus cells suspension on composition of vaginal microflora of mice under immunosupression

Vìsnik Dnìpropetrovsʹkogo Unìversitetu: Serìâ Bìologìâ, Ekologìâ, 2009
The influence of intravaginal administration of cells of indigenous strain of Staphylococcus aureus on composition of vaginal microbiocenosis was studied.
O. S. Voronkova, E. A. Sirokvasha, T. M. Polishko, A. I. Vinnikov   +3 more
doaj   +1 more source

Development and Evaluation of a Thermosensitive In Situ Gel Formulation for Intravaginal Delivery of Lactobacillus gasseri

Pharmaceutics, 2022
In situ administration of vaginal probiotics has been proposed as an effective prevention strategy against gynecological diseases caused by microecological disorders.
Ye Zhao, Tianyuan Wang, Ziyi Chen, Hao Ren, Ping Song, Yingying Zhu, Shan Liang, Chimeng Tzeng   +7 more
doaj   +1 more source

Intravaginal Delivery of Oxybutynin: An Alternative Administration Route to Improve its Pharmacokinetic and Pharmacodynamic Effects

European Urology Open Science
Background and objective: While oxybutynin is the most efficacious oral antimuscarinic treatment to reduce incontinence episodes in patients with an overactive bladder, oxybutynin is often discontinued due to significant side effects.
Sophie I. Peltenburg, Anouk C. Meijs, Lisa Pagan, Emily Somohardjo, Henk W. Elzevier, Janneke I.M. van Uhm, Marije E. Otto, Maria J. Juachon, Pamela Strugala, Alexa J. Tibboel, Koos Burggraaf, Bart W.J. Hellebrekers, Naomi B. Klarenbeek   +12 more
doaj   +1 more source

Research of acute toxicity of the drug HEXIA

Фармацевтичний журнал, 2018
Diseases of the genitourinary system caused by pathogenic and potentially pathogenic microorganisms, which result into disbiosis of urinary organs, remain an urgent problem of dermatovenereology, gynecology and urology, despite the fact that there is a ...
V. L. Karbovskyy, I. A. Shevchuk, O. V. Kurkina, T. Ye. Makovska   +3 more
doaj   +1 more source

Development of 3D-printed vaginal devices containing metronidazole for alternative bacterial vaginosis treatment

International Journal of Pharmaceutics: X, 2023
Bacterial vaginosis (BV) is an abnormal condition caused by the change of microbiota in the vagina. One of the most common bacteria found in the case of BV is Gardnerella vaginalis, which is categorised as anaerobic facultative bacteria.
Emilia Utomo, Juan Domínguez-Robles, Qonita Kurnia Anjani, Camila J. Picco, Anna Korelidou, Erin Magee, Ryan F. Donnelly, Eneko Larrañeta   +7 more
doaj   +1 more source

Bonneville Power Administration 1998 Annual Report.

, 1998
This is the 1998 annual report to the President by the Administrator and Chief Executive Officer of the Bonneville Power Administration. The topics of the report include financial highlights, letter to the President, review of 1998, financial data ...
United States. Bonneville Power Administration.
core   +1 more source

Intravaginal administration of metformin HCL loaded nanoemulgel for treatment of PCOS: in-vitro and in-vivo study [PDF]

Brazilian Journal of Pharmaceutical Sciences
Metformin HCL (MET-HCL), is a Biguanide derivative, most effective agent in treatment of PCOS. The focus of the present study was on developing and optimizing a nanoemulsion formulation.
Mukesh Ratnaparkhi, Bhagyashri Binawade, Shailendra Salvankar, Manoj Aswar, Prachi Jadhav, Pratik Parhad, Supriya Bhangare, Sampada Dalvi   +7 more
doaj   +2 more sources

Heterologous prime-boost vaccination based on Polymorphic protein D protects against intravaginal Chlamydia trachomatis infection in mice

Scientific Reports, 2022
The control of the worldwide spread of sexually transmitted Chlamydia trachomatis (Ct) infection urgently demands the development of a preventive vaccine.
Romina Cecilia Russi, Diego Del Balzo, Agustín Luján, Ivana Gabriela Reidel, María Inés García, Carolina Veaute, María Teresa Damiani   +6 more
doaj   +1 more source