Results 31 to 40 of about 1,789,709 (166)

Intravaginal Gel for Sustained Delivery of Occidiofungin and Long-Lasting Antifungal Effects

Gels, 2023
Fungal infections are caused by opportunistic pathogens that can be life threatening or debilitating. Candida spp. are becoming increasingly resistant to current clinically approved antifungal therapeutics.
Andrew Cothrell, Kevin Cao, Rachele Bonasera, Abraham Tenorio, Ravi Orugunty, Leif Smith   +5 more
doaj   +1 more source

Abortion caused by intravaginal self-administration of Misoprostol: a case report

Romanian Journal of Legal Medicine, 2019
The authors present a case of a 38 years old woman, 21 weeks pregnant, that went to the emergency department, where she gave birth to a stillborn male fetus. A gynaecological examination revealed three partially dissolved tablets in the vagina. Chemical laboratory tests on the tablets showed they were Misoprostol (MP) tablets.
Martina Focardi, Antonella Bosco, Francesca Castiglione, Gian Luca Bartolucci, Barbara Gualco, Valentina Bugelli   +5 more
openaire   +2 more sources

Utility of Pelvic Floor Therapy and Behavioral Interventions in the Neurogenic Lower Urinary Tract Dysfunction (NLUTD) Population

Neurourology and Urodynamics, EarlyView.
ABSTRACT Aims Neurogenic lower urinary tract dysfunction (NLUTD) describes a wide range of symptoms depending on neurologic diagnosis and the resulting bladder and sphincter dysfunction. This narrative review is designed to address the question regarding which NLUTD population benefits most from pelvic floor therapy and behavioral interventions, and ...
Sara M. Lenherr
wiley   +1 more source

Design, development and optimisation of veterinary intravaginal controlled release drug delivery systems [PDF]

, 2014
This Thesis begins by discussing the application of controlled drug delivery to the intravaginal delivery of hormones to control the oestrous cycle of farmed animals, with particular emphasis on the delivery of progestagens to cattle and sheep.
Ogle, Colin Roger
core  

Amino-functionalized poloxamer 407 with both mucoadhesive and thermosensitive properties: preparation, characterization and application in a vaginal drug delivery system

Acta Pharmaceutica Sinica B, 2017
Lack of mucoadhesive properties is the major drawback to poloxamer 407 (F127)-based in situ hydrogels for mucosal administration. The objective of the present study was to construct a novel mucoadhesive and thermosensitive in situ hydrogel drug delivery ...
Liqian Ci, Zhigang Huang, Yu Liu, Zhepeng Liu, Gang Wei, Weiyue Lu   +5 more
doaj   +1 more source

Sorafenib Nanomicelles Effectively Shrink Tumors by Vaginal Administration for Preoperative Chemotherapy of Cervical Cancer

Nanomaterials, 2021
To investigate the potential of sorafenib (SF) in preoperative chemotherapy for cervical cancer to reduce tumor volume, sorafenib micelles (SF micelles) with good stability and high drug loading were designed.
Jun Wang, Fengmei Lv, Tao Sun, Shoujin Zhao, Haini Chen, Yu Liu, Zhepeng Liu   +6 more
doaj   +1 more source

Core stability in women with and without chronic pelvic pain

PM&R, EarlyView.
Abstract Background Physical activity (PA) and core stability levels are unknown for women with musculoskeletal chronic pelvic pain (CPP) compared to healthy women. At this time, there is no validated treatment method aimed specifically at CPP. Objective To elucidate the PA habits and core stability of women with and without CPP.
Hannah V. Chatwin, Abhilasha Kumar, Michael Wesolowski, Laura Glaser, Colleen M. Fitzgerald, Stacey Bennis   +5 more
wiley   +1 more source

Avaliação da resposta imune celular contra HIV em camundongos imunizados pela via intravaginal com uma vacina de adenovírus recombinante [PDF]

, 2006
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas. Programa de Pós-Graduação em BiotecnologiaVacinas contra HIV que estimulem resposta imune de mucosas, especialmente no trato genital feminino, podem ser mais ...
Souza, Ana Paula Duarte de
core  

Determination of fenticonazole in human plasma by HPLC–MS/MS and its application to pharmacokinetic studies

Journal of Pharmaceutical Analysis, 2017
Two simple and sensitive high performance liquid chromatography–tandem mass spectrometry (HPLC–MS/MS) methods were developed and validated for the determination of fenticonazole in human plasma after percutaneous and intravaginal administration ...
Weixing Mao, Yiya Wang, Wenhui Hu, Feifei Jiao, Hongwei Fan, Li Ding   +5 more
doaj   +1 more source

Vaginal Oestrogen Therapy for Postmenopausal Women Undergoing Prolapse Surgery: A Multicentre Double‐Blind Randomised Placebo‐Controlled Clinical Trial

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Objective To determine whether vaginal oestrogen therapy improves outcomes after prolapse surgery in postmenopausal women. Design Double‐blind, randomised, placebo‐controlled trial with 12 month follow‐up. Setting Multicentre, 22 hospitals in the Netherlands.
Eva V. Vodegel, Krista van Rest, Leonie Speksnijder, Astrid Vollebregt, Albert Adriaanse, Eveline J. Roos, Franca Gerards, Wilbert Spaans, Marko Sikkema, Joggem Veen, Flora Vernooij, Marinus van der Ploeg, Jan‐Paul W. R. Roovers, the EVA Study Group, Alfredo L. Milani, Mirjam Weemhoff, Anne Damoiseaux, Heleen van Dongen, Marieke Mous, Pieternel Steures, Geerte van de Pol, Bart Broekman, Fernando Tjin Asjoe, Jolande van der Stege, Ronald Mouw, Ruben G. Duijnhoven   +25 more
wiley   +1 more source