Results 51 to 60 of about 74,108 (188)

One‐Step Immobilized Phage Depolymerase Coatings for Catheter‐Related Bloodstream Infections

Advanced Science, EarlyView.
Catheter‐related bloodstream infections (CRBSI) caused by drug‐resistant Gram‐negative bacteria remain a major clinical challenge. Here, a polydopamine‐assisted depolymerase coating degrades bacterial capsules and restores serum‐mediated killing, effectively suppressing biofilms and reducing bacterial burden in vitro, ex vivo, and in vivo, presenting a
Lingkai Dong, Xingjin Li, Tao Hu, Qianqian Lu, Xiaoxu Zhang, Xi Chen, Yifan Luo, Zhong Zuo, Ronald Man Yeung Wong, Miao Xu, Tiancong Zhao, Sharon Shui Yee Leung   +11 more
wiley   +1 more source

Intravascular hemolysis and mean red blood cell age in athletes

, 2006
PURPOSE: Since the observation that mechanical stress causes red blood cell (RBC) destruction, foot-strike hemolysis has been used to explain sports anemia and RBC rejuvenation in athletes. Recently gained knowledge questions the importance of mechanical
Robinson, Yohan,, Böning, Dieter, Dieter, Böning, Cristancho, E., Robinson, Yohan, Cristancho, Edgar   +5 more
core   +1 more source

Clostridium perfringens sepsis after pancreatoduodenectomy: a case report

Surgical Case Reports, 2022
Background Clostridium perfringens sepsis associated with massive intravascular hemolysis has an extremely poor prognosis. We here report a case of C. perfringens sepsis associated with massive intravascular hemolysis that developed secondary to a post ...
Goro Takahashi, Yoshiharu Nakamura, Tomohiro Hayakawa, Takashi Ono, Kazuhiko Endo, Hiroshi Yoshida   +5 more
doaj   +1 more source

Targeting B‐Cell‐Activating Factor and Its Receptor in Immune Thrombocytopenia and Warm Autoimmune Hemolytic Anemia

American Journal of Hematology, EarlyView.
ABSTRACT Current treatments for immune thrombocytopenia (ITP) and warm autoimmune hemolytic anemia (wAIHA), rare autoimmune diseases in which autoreactive B cells play a major role, can lead to high response rates; however, for many patients these responses are not durable or maintained after treatment discontinuation.
Matthieu Mahévas, Nichola Cooper, Vickie McDonald, Karina Yazdanbakhsh, Wilma Barcellini   +4 more
wiley   +1 more source

Hemolysis and its outcome following percutaneous closure of cardiac defects among children and adolescents: a prospective study

Italian Journal of Pediatrics, 2019
Background Transcatheter closure of intracardiac defects might be complicated by intravascular hemolysis. We evaluated hemolysis and its outcome after transcatheter closure of these defects.
Hamid Amoozgar, Romeileh Soltani, Mohammadreza Edraki, Nima Mehdizadegan, Hamid Mohammadi, Gholamhossein Ajami, Mohammad Borzouee, Amir Naghshzan, Kambiz Keshavarz   +8 more
doaj   +1 more source

Splenic Tropism and Spleen‐Modulated Systemic Inflammation in Acute Plasmodium vivax Malaria

American Journal of Hematology, EarlyView.
ABSTRACT In chronic Plasmodium vivax (Pv) infection, the spleen accounts for over 98% of total‐body parasite biomass. Whether splenic tropism also occurs in acute infection and how the spleen influences pathogenesis have not been systematically explored. In Papua, Indonesia, we compared clinical and hematology data in 24 spleen‐intact and 25 previously
Steven Kho, Hasrini Rini, Noy N. Kambuaya, Syawal Satria, Freis Candrawati, Putu A. I. Shanti, King Alexander, Benediktus Andries, Aisah R. Amelia, Anjana Rai, Kim A. Piera, Agatha M. Puspitasari, Ristya Amalia, Pak Prayoga, Leo Leonardo, Maulina Hafidzah, Theo Situmorang, Dewi S. Margayani, Desandra A. Rahmayenti, Pengxing Cao, Enny Kenangalem, Leily Trianty, Damian Oyong, Julie A. Simpson, Rintis Noviyanti, Pierre A. Buffet, Jeanne R. Poespoprodjo, Nicholas M. Anstey   +27 more
wiley   +1 more source

Ceftriaxone‐associated immune haemolytic anaemia: A patient‐level systematic review

British Journal of Clinical Pharmacology, EarlyView.
Abstract Ceftriaxone can cause acute haemolysis. Its clinical presentation, risk factors, and outcomes remain incompletely characterized. We conducted a systematic review of published cases with patient‐level data, following international guidelines and with registration in PROSPERO (CRD420261338709). Reports were identified through three bibliographic
Sonja Miotti, Giada Wyttenbach, Mario G. Bianchetti, Camilla Lavagno, Pietro Camozzi, Gregorio P. Milani, Renato Gualtieri, Sebastiano A. G. Lava, Pietro B. Faré, Simone Janett   +9 more
wiley   +1 more source

Sequential catalytic nanosystem of carbon dots and uricase integrated with polydopamine for therapy of gouty wound ulceration

BMEMat, EarlyView.
Sequential dual‐catalytic treatment of the gout wound ulceration process by CDs‐Uri@PDA. (a) Synthesis steps and morphology of CDs‐Uri@PDA. (b) Sequential treatment process and mechanism of CDs‐Uri@PDA for gout wound ulceration according to (i) uric acid reduction, (ii) antibacterial activity, and (iii) anti‐inflammatory effects.
Yonglan Yang, Yang Yang, Pengpeng Ma, Ruiqi Zhu, Xia Pan, Shaoling Zheng, Bo Chen, Yanli Jin, Youcong Gong, Jie Liu, Tianwang Li, Xu Chen   +11 more
wiley   +1 more source

Intravascular hemolysis activates complement via cell-free heme and heme-loaded microvesicles

, 2018
International audienceIn hemolytic diseases, such as sickle cell disease (SCD), intravascular hemolysis results in the release of hemoglobin, heme, and heme-loaded membrane microvesicles in the bloodstream.
Knockaert, Samantha, Monika Edler, Helena Rajaratnam, Veronique Fremeaux-Bacchi, Tania Robe-Rybkine, Fremeaux-Bacchi, Veronique, Bouzekri, Sanah, Charue, Dominique, Sanah Bouzekri, Noe, Remi, Sophie Chauvet, Miescher, Sylvia, Brinkman, Nathan, Chauvet, Sophie, Dimitrov, Jordan, Merle, Nicolas, Marie Frimat, Petrillo, Sara, Emanuela Tolosano, Sylvain Le Jeune, Tolosano, Emanuela, Thomas Gentinetta, Marion Rabant, Jordan D. Dimitrov, Rabant, Marion, Nicolas S. Merle, Rajaratnam, Helena, Marie Le-Hoang, Lubka T. Roumenina, Samantha Knockaert, Pascal Houillier, Le Jeune, Sylvain, Edler, Monika, Frimat, Marie, Gentinetta, Thomas, Olivier P. Blanc-Brude, Le-Hoang, Marie, Robe-Rybkine, Tania, Sylvia Miescher, Anne Grunenwald, Grunenwald, Anne, Nathan Brinkman, Gnemmi, Viviane, Blanc-Brude, Olivier, Figueres, Marie-Lucile, Marie-Lucile Figueres, Houillier, Pascal, Viviane Gnemmi, Roumenina, Lubka, Dominique Charue, Sara Petrillo, Remi Noe   +51 more
core   +1 more source

Implantable electrochemical sensors for continuous blood monitoring

FlexMat, EarlyView.
Implantable electrochemical sensors enable direct, in situ, and continuous blood monitoring, shifting diagnosis from population‐based averages to dynamic, individualized analysis. This review systematically examines the influence of the unique blood properties on sensor design.
Kuangyi Zou, Yuanzhen Wang, Haidong Wang, Ye Zhang   +3 more
wiley   +1 more source