Results 21 to 30 of about 27,000 (253)

Concerns of the anesthesiologist: anesthetic induction in severe sepsis or septic shock patients [PDF]

Korean Journal of Anesthesiology, 2012
Septic patients portray instable hemodynamic states because of hypotension or cardiomyopathy, caused by vasodilation, thus, impairing global tissue perfusion and oxygenation threatening functions of critical organs.
Seok Hwa Yoon
doaj   +1 more source

Cardiac output and the pharmacology of general anesthetics: a narrative review

Colombian Journal of Anesthesiology, 2023
The relationship between cardiac output and anesthetic drugs is important to anesthesiologists, since cardiac output determines the speed with which a drug infused into the bloodstream reaches its target and the intensity of the drug’s effect.
Elena Simón-Polo, Jose Vicente Catalá-Ripoll, José Ángel Monsalve-Naharro, Manuel Gerónimo-Pardo   +3 more
doaj   +1 more source

Comparative analysis of the effects of inhalational and intravenous anesthetics on hemodynamic variability and cardiovascular complications in patients undergoing general anesthesia – a review of current evidence

Journal of Education, Health and Sport
Background. Patient hemodynamic stability during general anesthesia is a crucial factor, managing which helps avoid many complications, especially cardiovascular ones. Intravenous and inhaled anesthetics affect the human body differently, have different
Sandra Drabik, Maja Gałuszka, Aleksandra Gałuszka, Kamila Krycia, Karolina Mazur, Karolina Różycka, Magdalena Mulawa, Emilia Piaszczyńska, Dominika Matacz, Adrianna Adamczyk   +9 more
doaj   +1 more source

Inhalational versus total intravenous anesthesia in noncardiac surgery: a comparative review of clinical outcomes [PDF]

Korean Journal of Anesthesiology
Inhalational anesthetics have long been the cornerstone of general anesthesia in noncardiac surgery owing to their reliable pharmacokinetics, ease of administration, and cardiopulmonary benefits such as bronchodilation and myocardial preconditioning ...
Ah Ran Oh, Jungchan Park
doaj   +1 more source

Inhalational versus intravenous anesthetic for cerebrovascular accident outcomes after surgical revascularization for adult moyamoya disease

BMC Anesthesiology
Purpose To compare the effects of inhalational anesthetics and intravenous anesthetics on the neurological function of patients with moyamoya disease (MMD) after vascular bypass surgery.
Yifei Cheng, Chaochao Zha, Xuehua Che, Yingwei Wang   +3 more
doaj   +1 more source

Safety and efficacy of target-controlled infusion versus intermittent bolus administration of propofol for sedation in colonoscopy: a randomized controlled trial

Brazilian Journal of Anesthesiology, 2023
Background: Our objective was to compare the safety and efficacy of Target-Controlled Infusion (TCI) versus intermittent bolus of propofol for colonoscopy sedation.
Igor Seror Cuiabano, Priscila de Miranda Garbin, Norma Sueli Pinheiro Módolo, Paulo do Nascimento, Junior   +3 more
doaj   +1 more source

Personalized Zebrafish Models for Fusion‐Positive Pediatric Sarcomas

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Clinical sequencing efforts have revolutionized our approaches to categorizing pediatric cancers in real time. This has dramatically improved our ability to profile pediatric tumors, identify actionable vulnerabilities, and influence clinical care.
Lisa H. Hall, Emma N. Harrison, Genevieve C. Kendall   +2 more
wiley   +1 more source

General Anesthetics: Aspects of Chirality, Pharmacodynamics, and Pharmacokinetics

Pharmaceuticals
The introduction of general anesthetics in the mid-19th century is considered one of the greatest contributions to medical practice. It was the first time that complicated surgical interventions became feasible, without putting an excessive strain on the
Ružena Čižmáriková, Ladislav Habala, Jindra Valentová   +2 more
doaj   +1 more source

The effect of intravenous and inhalation anesthesia in general on the cognition of elderly patients undergoing non-cardiac surgery: a systematic review and meta-analysis

Frontiers in Medicine, 2023
BackgroundPostoperative cognitive dysfunction (POCD) is a postoperative complication that often occurs in the elderly. This systematic review and meta-analysis aimed to compare intravenous anesthetics (propofol) with inhalation anesthetics (sevoflurane ...
Leilei Huang, Yong Zhang
doaj   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source