Results 121 to 130 of about 51,949 (245)

Pantothenic Acid Protects Neurons After Ischemic Stroke by Targeting ID3 to Restore Action Potential Amplitude

Journal of Neuroscience Research, Volume 104, Issue 5, May 2026.
Ischemic stroke reduces ID3 expression and impairs neuronal action potential amplitude and frequency. Pantothenic acid (PA) targets and upregulates ID3, restoring amplitude but not frequency. The PA‐ID3‐amplitude axis represents a potential neuroprotective strategy.
Hongqiao Chen, Mingli Chen, Lian Meng, Xing Wei, Yan Qin, Zhumei Bi   +5 more
wiley   +1 more source

Development and Reliability Test of the Intravenous Thrombolysis Intention Scale for Patients With Acute Ischemic Stroke

Nursing Open, Volume 13, Issue 5, May 2026.
ABSTRACT Aim This study aimed to develop a tool for assessing the willingness of patients with acute ischemic stroke (AIS) and high‐risk populations to undergo intravenous thrombolysis, and to evaluate its validity and reliability. Design The study aimed to validate an instrument for assessing intent and was conducted in three phases.
Dazhen Li, Keke Ma, Wenfeng Fan, Renke Gao, Caixia Yang, Li‐na Guo, Xiaofang Dong, Peihua Lv, Min Wang, Huanhuan Gao, Yanjin Liu, Yuanli Guo   +11 more
wiley   +1 more source

Functional Stroke Mimics: Patient Characteristics, CT‐Based Multimodal Imaging and Long‐Term Outcome in a Comparative Cohort Study

European Journal of Neurology, Volume 33, Issue 5, May 2026.
Functional stroke‐like episodes are increasingly recognised as stroke mimics. In a study of 25 cases who underwent hyperacute multimodal CT, patients were younger than their counterparts with acute ischaemic strokes and often had a psychiatric and functional disorder background.
Filipa Bastos, Davide Strambo, Alexander Salerno, Vincent Dunet, Selma Aybek, Patrik Michel   +5 more
wiley   +1 more source

Stroke Severity Affects Timing: Time From Stroke Code Activation to Initial Imaging is Longer in Patients With Milder Strokes. [PDF]

, 2018
Optimizing the time it takes to get a potential stroke patient to imaging is essential in a rapid stroke response. At our hospital, door-to-imaging time is comprised of 2 time periods: the time before a stroke is recognized, followed by the period after ...
Dhamoon, Mandip, Kwei, Kimberly T., Liang, John W., Tuhrim, Stanley, Wilson, Natalie   +4 more
core   +1 more source

Insights Into Remote Ischemic Conditioning miRNA Effects on Brain Endothelial Cells During Ischemia–Reperfusion

Microcirculation, Volume 33, Issue 4, May 2026.
ABSTRACT Objective Acute ischemic stroke (AIS) is one of the leading causes of death and disabilities, and as such, it is of utmost importance to identify novel treatment options. Remote ischemic conditioning (RIC) is a promising non‐invasive treatment that is thought to activate the body's own protective mechanisms against damaging ischemia.
Katrine Tang Stenz, Jesper Just, Zenghui Huang, Thomas Ravn Lassen, Kristian Vissing, Xiu‐Jie Wang, Kim Ryun Drasbek   +6 more
wiley   +1 more source

Study on the efficacy and safety of aspirin combined with clopidogrel pretreatment before rt⁃PA intravenous thrombolysis in patients with cardioembolism

Chinese Journal of Contemporary Neurology and Neurosurgery, 2020
Objective To investigate the efficacy and safety of aspirin combined with clopidogrel pretreatment before intravenous thrombolysis with rt ⁃ PA in patients with cardioembolism (CE). Methods Three hundred and thirteen patients with CE treated with rt ⁃ PA
Chen⁃hua LI, Shan⁃shan ZHANG, Yu⁃xin WANG, Yan CHEN, Chen⁃hao ZHANG, Pei⁃lan ZHANG   +5 more
doaj  

Analysis of risk factors for early neurological deterioration after intravenous thrombolysis in patients with acute ischemic stroke

Frontiers in Neurology
ObjectiveThe aim of this study is to examine the potential risk factors contributing to early neurological deterioration (END) following intravenous thrombolysis in patients diagnosed with acute ischemic stroke (AIS).MethodsClinical data was gathered ...
Jungang Fang, Hui Sun, Xinyu Lu
doaj   +1 more source

Intravenous thrombolysis for acute stroke.

Cleveland Clinic Journal of Medicine, 2004
Intravenous t-PA is effective if given to appropriate patients within 3 hours of stroke onset, and its effectiveness increases even within the first 3 hours when given as soon as possible. t-PA is reasonably safe if used in a carefully defined manner that ensures close attention to blood pressure, careful patient monitoring, no use of heparin and ...
openaire   +2 more sources

Clinical and epidemiological overview of hyperacute ischemic stroke patients treated with intravenous thrombolysis

The Egyptian Journal of Internal Medicine
Background Hyperacute ischemic stroke is a type of ischemic stroke that occurs rapidly and suddenly due to blockage of blood flow to the brain, with onset within 0–24 h.
Lisda Amalia, Putri Qonitah
doaj   +1 more source

Thrombolytics in Pediatric Stroke: Imaging Modalities [PDF]

, 2020
Thrombolytics in Pediatric Stroke: Imaging Modalities Katherine Au, Dept. of Biomedical Engineering, with Dr. Bisi Hollist, Inova Neuroscience and Spine Institute We report the potential danger associated with an initial neuroimaging-negative cerebral ...
Au, Katherine, Hollist, Bisi
core   +1 more source