Results 111 to 120 of about 248,430 (244)
ESC Heart Failure, Volume 12, Issue 2, Page 1514-1522, April 2025.
Takamasa Iwai +4 more
wiley +1 more source
ABSTRACT Superior vena cava (SVC) syndrome is an uncommon complication of transvenous cardiac device leads. Diagnosis may be challenging due to gradually developing and nonspecific symptoms. Furthermore, anatomical imaging does not always reflect the hemodynamic significance of venous stenosis.
Fenna Daniëls +5 more
wiley +1 more source
Safety and efficacy of thrombolysis with intravenous alteplase in older stroke patients.
Stroke is a common cause of death and persisting disability worldwide, and thrombolysis with intravenous alteplase is the only approved treatment for acute ischaemic stroke.
Sarikaya, Hakan
core +1 more source
This study uncovers hierarchical coordination between K11 lactylation and S199 phosphorylation of CKB in cerebral ischemia‐reperfusion injury. Such dual modifications potentiate CKB enzymatic function, remodel energy metabolism, alleviate oxidative stress and neuronal damage, and represent a viable therapeutic target for stroke treatment.
Chao Duan +17 more
wiley +1 more source
Acute ischemic stroke due to large vessel occlusion is associated with rapid intravascular immune activation. Analysis of arterial blood sampled distal to the thrombus during mechanical thrombectomy revealed increased extracellular adenosine triphosphate (ATP) and interleukin‐1β (IL‐1β) levels, evidence of inflammasome priming in monocytes, and ...
Justine Münsterberg +33 more
wiley +1 more source
ABSTRACT Objective To investigate the natural course of cerebral small vessel disease (CSVD) manifested as pure thalamic infarction (PTI) and identify predictors of 90‐day clinical prognosis and 1‐year recurrent major adverse cardiovascular/cerebrovascular events (MACE).
Huang Qiang, Cui Ying, Zhang Yongbo
wiley +1 more source
Intravenous thrombolysis for acute stroke.
Intravenous t-PA is effective if given to appropriate patients within 3 hours of stroke onset, and its effectiveness increases even within the first 3 hours when given as soon as possible. t-PA is reasonably safe if used in a carefully defined manner that ensures close attention to blood pressure, careful patient monitoring, no use of heparin and ...
openaire +2 more sources
ABSTRACT Background and Purpose The C‐reactive protein–triglyceride–glucose index (CTI), capturing insulin resistance (IR) and systemic inflammation, is related to stroke prognosis in general, but has not yet been studied with respect to functional outcomes after endovascular thrombectomy (EVT).
Jing Bian +9 more
wiley +1 more source
ABSTRACT Background Dual antiplatelet therapy (DAPT) was noninferior to alteplase in nondisabling minor stroke (NIHSS 0 to 5). Given potential benefit of DAPT in minor stroke with large artery atherosclerosis (LAA) and of alteplase in stroke with NIHSS 4–5, we hypothesize that neurological deficit and LAA may affect efficacy of DAPT versus alteplase in
Yu Cui +3 more
wiley +1 more source
Visual summary of the comparative efficacy and safety of intravenous tenecteplase versus alteplase in posterior circulation ischemic stroke. ABSTRACT Background Posterior circulation ischemic stroke (PCIS) is associated with substantial morbidity and mortality, and the optimal intravenous thrombolytic strategy in this subgroup remains unclear.
Shaheer Bin Shafiq +11 more
wiley +1 more source

