Results 91 to 100 of about 248,430 (244)

Higher fibrinogen and neutrophil-to-lymphocyte ratio are associated with the early poor response to intravenous thrombolysis in acute ischemic stroke

Frontiers in Neurology
BackgroundInflammation and platelet activation play pivotal roles in acute ischemic stroke (AIS) pathogenesis. Early response to thrombolysis is a vital indicator for the long-term prognosis of AIS.
Mingzhu Deng, Kangping Song, Yangping Tong, Sufen Chen, Wei Xu, Guohua He, Jue Hu, Hui Xiao, Changmin Wan, Zhen Wang, Fangyi Li   +10 more
doaj   +1 more source

Stroke Following Facial Laser Resurfacing Procedure—A Case Report

Lasers in Surgery and Medicine, EarlyView.
ABSTRACT Objectives To describe the first reported case of embolic stroke with hemorrhagic conversion following a dermatologic energy‐based device procedure, highlighting its mechanism and clinical implications. Methods A detailed case review was conducted, including clinical presentation, imaging, and subsequent diagnostic workup. The patient provided
Tal Levy, Joel L. Cohen
wiley   +1 more source

Dose escalation of desmoteplase for acute ischemic stroke (DEDAS): evidence of safety and efficacy 3 to 9 hours after stroke onset [PDF]

, 2006
<p><b>Background and Purpose:</b> Desmoteplase is a novel plasminogen activator with favorable features in vitro compared with available agents.
Lees, K.R., Hacke, W.l, Sachara, C., Rowley, H.A., Furlan, A.J., Al, R.Y., Eyding, D., Albers, G.W., Soehngen, M., Warach, S.   +9 more
core   +1 more source

Noninvasive or minimally invasive neuromodulation in animal models of acute ischemic stroke: A systematic review and meta‐analysis

Neuroprotection, EarlyView.
This systematic review and meta‐analysis assessed the cytoprotective effects of neuromodulation in preclinical models of ischemic stroke. Pooled analyses showed that neuromodulation significantly reduced infarct volume and improved neurological outcomes.
Igor Caitano Salles, Mateus Paquesse Pellegrino, Jessica Borges Kroth, Clara Lucato dos Santos, Luca Schiliro Tristao, Jullyanna Sabrysna Morais Shinosaki, Wanderley Marques Bernardo, Adriana Bastos Conforto   +7 more
wiley   +1 more source

Intraocular hemorrhage in patients misdiagnosed with central retinal artery occlusion treated with thrombolysis

Frontiers in Neurology
IntroductionThe diagnosis of acute central retinal artery occlusion (CRAO) is commonly delayed in emergency departments (ED) where ophthalmologists are rarely available for immediate consultation.
Daniel V. Adamkiewicz, Christian Leal, Kevin Y. Yan, Sruthi Arepalli, Kevin Ferenchak, Blaine Cribbs, Riley J. Lyons, Étienne Bénard-Séguin, Étienne Bénard-Séguin, Étienne Bénard-Séguin, Nancy J. Newman, Nancy J. Newman, Nancy J. Newman, Valérie Biousse, Valérie Biousse   +14 more
doaj   +1 more source

Efficacy and Safety of Intravenous Thrombolysis in Patients with Unknown Onset Stroke: A Meta-Analysis

Behavioural Neurology, 2019
Objectives. Unknown onset stroke (UOS) is usually excluded from intravenous thrombolysis concerning the unclear symptom onset time. Attempts have been done to use thrombolytic therapy in these patients.
Di Luan, Yuanxiang Zhang, Qian Yang, Zhiming Zhou, Xianjun Huang, Shoucai Zhao, Lili Yuan   +6 more
doaj   +1 more source

Evaluation of the neurovascular pathway: The value of specialized training in reducing in-hospital stays and increasing IV thrombolysis rates. Experience of the neurovascular unit at EHU Oran from 2015 to 2024. [PDF]

Batna Journal of Medical Sciences
Introduction: Intravenous thrombolysis (IVT) significantly improves clinical outcomes in ischemic stroke; however, its clinical benefit diminishes rapidly over time.
Douniazede BADSI, Khadidja TERKI, Djawed SAYEH, Djamel CHAKRAR
doaj   +1 more source

Carbon dots as a smart nanoplatform for the blood‐brain barrier penetration and ischemic stroke therapy

Responsive Materials, EarlyView.
This review presents the structure and transport routes of the blood‐brain barrier, summarizes the ischemic stroke pathophysiological cascade, and discusses the BBB‐crossing mechanisms and multitarget therapeutic effects of carbon dots, demonstrating their promising theranostic potential for ischemic stroke.
Yanhan Huang, Xuan Hou, Haiping Zhao, Qi Kong, Xiayan Wang, Xiaokun Geng, Zaicheng Sun   +6 more
wiley   +1 more source

Value of Multimodal Computed Tomography Quantitative Analysis for Predicting Early Neurological Deterioration in Acute Ischemic Stroke Patients Undergoing Intravenous Thrombolysis

Clinical and Applied Thrombosis/Hemostasis
Objective We aimed to explore the performance of multimodal computed tomography (CT) quantitative analysis for predicting early neurological deterioration in acute ischemic stroke (AIS) patients undergoing intravenous thrombolysis.
Mo Chen MM, Yujia Zhai MBBS, Liangqun Rong MBBS, Xiue Wei MD, Haiyan Liu MM   +4 more
doaj   +1 more source

Cell‐Based Micro/Nanorobots: From Living Carriers to Living Therapeutic Specialists

SmartBot, EarlyView.
Cell‐based micro/nanorobots integrate evolutionarily acquired biological intelligence with engineered capabilities, offering new opportunities for precision medicine in vivo. However, the complex physiological environments of different organs pose significant challenges to their clinical translation.
Junfeng Wu, Zhaoyu Zhang, Ke Xu, Enkuo Li, Yuting Cui, Yuting Zhou, Huanyu Zhou, Beipei Zhang, Shuai Jiang, Xiaodong Wang, Jialin Jiang, Lianqing Liu, Niandong Jiao   +12 more
wiley   +1 more source