Results 51 to 60 of about 29,864 (215)

Hyperacute Interleukin‐1β Production and Neutrophil Extracellular Trap Formation in the Cerebral Circulation of Stroke Patients with Large Vessel Occlusion

Annals of Neurology, EarlyView.
Acute ischemic stroke due to large vessel occlusion is associated with rapid intravascular immune activation. Analysis of arterial blood sampled distal to the thrombus during mechanical thrombectomy revealed increased extracellular adenosine triphosphate (ATP) and interleukin‐1β (IL‐1β) levels, evidence of inflammasome priming in monocytes, and ...
Justine Münsterberg, Caspar Brekenfeld, Hanna Englert, Marius Piepke, Regine J. Dress, Martin Oertel, Tina Fischer, Romy Hackbusch, Mingming Zha, Haodi Cai, Christian Casar, Ines S. Schädlich, Leo Winter, Alina Jander, Karoline Degenhardt, Maxim Bester, Fabian Flottmann, Uta Hanning, Brigitte Holst, Anna Worthman, Johanna Hiefner, Berenike Rutz, Eckhard Schlemm, Götz Thomalla, Bettina H. Clausen, Ann M. Stowe, Immo Prinz, Thiruma V. Arumugam, Markus Glatzel, Thomas Renné, Jens Fiehler, Eva Tolosa, Tim Magnus, Mathias Gelderblom   +33 more
wiley   +1 more source

Intravenous thrombolysis for acute ischemic stroke

Diagnostic and Interventional Imaging, 2014
Intravenous thrombolysis (IVT) with alteplase remains the standard treatment for acute ischemic stroke. Although IVT can be started up to 4.5 hours after symptoms' onset, it is all the more effective and safe when started early. It allows a 10% absolute reduction in the risk of handicap or death at 3 months, despite a 2-7% risk of symptomatic ...
Turc, G., Isabel, C., Calvet, D.
openaire   +2 more sources

Mechanical Thrombus Aspiration for a Young STEMI Patient With Plaque Erosion: Time for a Stent‐Free Approach?

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT A 34‐year‐old man with no cardiovascular history presented with anterior ST‐elevation myocardial infarction and a large thrombotic occlusion of the mid left anterior descending artery. Following potent antithrombotic therapy and mechanical thrombus aspiration, angiography revealed vessel patency without residual significant stenosis, allowing ...
Domenico Simone Castiello, Francesco Greco, Antonio Curcio, Alberto Polimeni   +3 more
wiley   +1 more source

The mechanisms of reperfusion during in stroke patients treated with intravenous thrombolysis

Неврология, нейропсихиатрия, психосоматика, 2012
Systemic (intravenous) thrombolysis with recombinant tissue plasminogen activator (rt-PA) is a proved effective treatment modality in a certain group of patients with ischemic stroke (IS) in the first 4.5 hours after the onset of neurological symptoms ...
Maksim Alekseyevich Domashenko, M Yu Maksimova, M A Loskutnikov, A A Nikonov, V V Bryukhov, A S Suslin, M V Dreval, R N Konovalov   +7 more
doaj   +1 more source

Calcified Plaque Detachment: Alternative Calcified Plaque Modification After Coronary Intravascular Lithotripsy

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background Calcified plaque (CP) detachment (CD) and calcium fracture (CF) can occur following coronary intravascular lithotripsy (IVL). The extent to which CF alone facilitates stent expansion during CP modification with IVL remains unclear. Aims This study aimed to investigate the clinical implications of IVL‐induced CD.
Daisuke Naito, Akiko Matsuo, Takeru Kasahara, Keisuke Ota, Shinsaku Matsunaga, Norio Nakajima   +5 more
wiley   +1 more source

Intravenous Thrombolysis [PDF]

International Journal of Stroke, 2010
Thang H, Nguyen, Anh T L, Truong, Minh Ba, Ngo, Chau T Q, Bui, Quang V, Dinh, Tan C, Doan, Lien T K, Nguyen, Tan C, Phan, Mung V, Phan, Tuan V, Nguyen, Thanh V, Le   +10 more
openaire   +3 more sources

Predictive role of pre-thrombolytic hs-CRP on the safety and efficacy of intravenous thrombolysis in acute ischemic stroke

BMC Neurology, 2023
Purpose To investigate the predictive role of pre-thrombolytic high sensitivity C-reactive protein (hs-CRP) on the safety and efficacy of intravenous thrombolysis in patients with acute ischemic stroke (AIS).
Xu-Dong Cheng, Duo-Zi Wang, Qi Zhang, Jian-Hong Wang, Bing-Hu Li, Xin Zhang, Jing Zhang, Sen Zhou, Li-Jun Jia, Li-Rong Wang, Neng-Wei Yu   +10 more
doaj   +1 more source

Coronary Perforation During Excimer Laser Angioplasty in a Patient With Prior Thoracic Radiotherapy

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background Management of heavily calcified coronary lesions remains challenging despite advances in plaque‐modifying technologies. Excimer laser coronary angioplasty (ELCA) is an effective adjunctive strategy with a low risk of no‐reflow. Case Summary A 75‐year‐old woman with non–ST‐segment elevation acute coronary syndrome and severe left ...
Francesco Maria Sparasci, Alessandro Cafaro, Dionigi Fischetti, Alessandro Mandurino‐Mirizzi   +3 more
wiley   +1 more source

Clinical Outcomes of Drug‐Eluting Stents and Drug‐Coated Balloons in Tortuous Small Coronary Lesions

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background In small, tortuous coronary lesions, the long‐term comparative performance of drug‐coated balloon (DCB) angioplasty versus drug‐eluting stent (DES) treatment remains uncertain, despite both strategies being widely used in contemporary percutaneous coronary intervention (PCI) practice. Aims This study aimed to compare 3‐year clinical
Shunichiro Ishio, Takashi Nagasaka, Ryota Taniuchi, Shiro Amanai, Yohei Ishibashi, Noriaki Takama, Hideki Ishii   +6 more
wiley   +1 more source

Multi‐Cohort Analysis Reveals Genetic Predispositions to Clonal Hematopoiesis as Mutation‐Specific Risk Factors for Stroke

Advanced Genetics, Volume 6, Issue 1, March 2025.
This study comprehensively evaluated the differential effect of clonal hematopoiesis (CH) mutations on the risk of various stroke subtypes and functional recovery. It shows that TET2 is associated with small vessel stroke possibly via a pro‐inflammatory pathway. Abstract Recent observational studies have found an association between Clonal Hematopoesis
Shuyang Lin, Yang E. Li, Yan Wang
wiley   +1 more source