Results 51 to 60 of about 29,812 (199)

The mechanisms of reperfusion during in stroke patients treated with intravenous thrombolysis

Неврология, нейропсихиатрия, психосоматика, 2012
Systemic (intravenous) thrombolysis with recombinant tissue plasminogen activator (rt-PA) is a proved effective treatment modality in a certain group of patients with ischemic stroke (IS) in the first 4.5 hours after the onset of neurological symptoms ...
Maksim Alekseyevich Domashenko, M Yu Maksimova, M A Loskutnikov, A A Nikonov, V V Bryukhov, A S Suslin, M V Dreval, R N Konovalov   +7 more
doaj   +1 more source

Unveiling the Microvasculature: The Index of Microcirculatory Resistance and Its Expanding Role in Cardiovascular Care

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Index of microcirculatory resistance (IMR) is a cutting‐edge, wire‐based tool that advances the capability assessment of coronary microvascular function. By utilizing distal coronary pressure and mean transit time under maximal hyperemia, IMR delivers consistent, reproducible insights into the microvasculature's dynamic health.
Joanna Sohn, Matthew A. Soderstrom, Ariana Ramirez, John‐Henry Dean, Raj Shah, Debanshu Roy, Kenneth Stone, Ariel Vinas, Bryan Ramsey, Charles Lin, Robert Chilton   +10 more
wiley   +1 more source

Mechanical Thrombus Aspiration for a Young STEMI Patient With Plaque Erosion: Time for a Stent‐Free Approach?

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT A 34‐year‐old man with no cardiovascular history presented with anterior ST‐elevation myocardial infarction and a large thrombotic occlusion of the mid left anterior descending artery. Following potent antithrombotic therapy and mechanical thrombus aspiration, angiography revealed vessel patency without residual significant stenosis, allowing ...
Domenico Simone Castiello, Francesco Greco, Antonio Curcio, Alberto Polimeni   +3 more
wiley   +1 more source

Predictive role of pre-thrombolytic hs-CRP on the safety and efficacy of intravenous thrombolysis in acute ischemic stroke

BMC Neurology, 2023
Purpose To investigate the predictive role of pre-thrombolytic high sensitivity C-reactive protein (hs-CRP) on the safety and efficacy of intravenous thrombolysis in patients with acute ischemic stroke (AIS).
Xu-Dong Cheng, Duo-Zi Wang, Qi Zhang, Jian-Hong Wang, Bing-Hu Li, Xin Zhang, Jing Zhang, Sen Zhou, Li-Jun Jia, Li-Rong Wang, Neng-Wei Yu   +10 more
doaj   +1 more source

Multi‐Cohort Analysis Reveals Genetic Predispositions to Clonal Hematopoiesis as Mutation‐Specific Risk Factors for Stroke

Advanced Genetics, Volume 6, Issue 1, March 2025.
This study comprehensively evaluated the differential effect of clonal hematopoiesis (CH) mutations on the risk of various stroke subtypes and functional recovery. It shows that TET2 is associated with small vessel stroke possibly via a pro‐inflammatory pathway. Abstract Recent observational studies have found an association between Clonal Hematopoesis
Shuyang Lin, Yang E. Li, Yan Wang
wiley   +1 more source

Intravenous Thrombolysis [PDF]

International Journal of Stroke, 2010
Thang H, Nguyen, Anh T L, Truong, Minh Ba, Ngo, Chau T Q, Bui, Quang V, Dinh, Tan C, Doan, Lien T K, Nguyen, Tan C, Phan, Mung V, Phan, Tuan V, Nguyen, Thanh V, Le   +10 more
openaire   +3 more sources

Machine Learning Methods to Predict the Length of Stay for Acute Stroke: A Scoping Review and Meta‐Analysis

Health Care Science, EarlyView.
Current machine learning models for predicting the length of stay for acute stroke lack clinical utility and reliability. This scoping review highlights areas for improvement to develop more robust, interpretable, generalizable, and clinically actionable models that optimize personalized clinical pathways and support precise decision‐making for stroke ...
Zhenran Xu, Monique F. Kilkenny, Tzu‐Yung Kuo, Jia Rong, Lachlan L. Dalli   +4 more
wiley   +1 more source

Heparan sulfate and glycomimetics: Advances in synthesis and biological applications for post‐stroke neurorepair

Neuroprotection, EarlyView.
ECM, extracellular matrix; BDNF, brain‐derived neuroptrophic factor; FGF, fibroblast growth factor; VEGF, vascular endothelial growth factor. Abstract Heparan sulfate, a structurally diverse glycosaminoglycan that is abundant in the central nervous system (CNS), orchestrates essential processes fundamental to neural plasticity, neurorepair, and ...
Mozammel H. Bhuiyan, Madeleine J. Smith, Simon F. R. Hinkley, Andrew N. Clarkson   +3 more
wiley   +1 more source

A catastrophic confluence: Concurrent subarachnoid haemorrhage and acute mesenteric ischaemia

Surgical Practice, EarlyView.
Abstract Background Acute mesenteric ischaemia (AMI) and subarachnoid haemorrhage (SAH) are life‐threatening emergencies with diametrically opposed treatment requirements regarding anticoagulation. This report describes a rare, complex case where both conditions occurred simultaneously, creating a significant therapeutic dilemma. Case presentation A 64‐
Ip Ki Fung Shavonne
wiley   +1 more source

Interventional oncology in children: Where are we now?

Journal of Medical Imaging and Radiation Oncology, EarlyView.
Abstract Paediatric Interventional Oncology (IO) lags behind adult IO due to a scarcity of specific outcome data. The suboptimal way to evolve this field is relying heavily on adult experiences. The distinct tumour types prevalent in children, such as extracranial germ cell tumours, sarcomas, and neuroblastoma, differ strongly from those found in ...
Premal Amrishkumar Patel, Fernando Gómez Muñoz   +1 more
wiley   +1 more source