Results 91 to 100 of about 99,964 (316)

Clearance of Intravitreal Voriconazole

open access: yesInvestigative Opthalmology & Visual Science, 2007
Purpose To investigate the elimination rate of voriconazole after intravitreal injection in rabbits.Intravitreal injections of 35 microg/0.1 mL voriconazole were administered to rabbits. Vitreous and aqueous humor levels of voriconazole were determined at selected time intervals (1, 2, 4, 8, 16, 24, and 48 hours), and the in vitreous half-life was ...
Ying-Cheng, Shen   +6 more
openaire   +2 more sources

Efficacy of Intravitreal Bevacizumab for Stage 3+ Retinopathy of Prematurity

open access: yesNew England Journal of Medicine, 2011
BACKGROUND Retinopathy of prematurity is a leading cause of childhood blindness worldwide. Peripheral retinal ablation with conventional (confluent) laser therapy is destructive, causes complications, and does not prevent all vision loss, especially in ...
H. Mintz‐Hittner   +2 more
semanticscholar   +1 more source

METTL14 Ameliorates Mitochondrial Dysfunction and Autophagy in Lens Epithelial Cells of Diabetic Cataracts via m6A Modification of RPL3

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Diabetic cataracts are a leading cause of blindness, with lens epithelial cells (LECs) exhibiting mitochondrial dysfunction and autophagy inhibition under high glucose (HG) conditions. Methyltransferase‐like 14 (METTL14), an RNA methyltransferase, regulates N6‐methyladenosine (m6A) RNA modification; however, its role in modulating ...
Rui Li   +4 more
wiley   +1 more source

Case of endophthalmitis following intravitreal injections of bevacizumab [PDF]

open access: yes, 2010
Shinya Komori1, Akira Sawada1, Tsutomu Oguni1, Kiyofumi Mochizuki1, Kiyofumi Ohkusu21Department of Ophthalmology, 2Department of Microbiology, Gifu University Graduate School of Medicine, Gifu, JapanPurpose: We report a case of infectious endophthalmitis
Akira Sawada   +3 more
core  

The efficacy of sleeve technique in primary nasolacrimal duct obstruction with a high lacrimal sac

open access: yesIndian Journal of Ophthalmology, 2014
Purpose: To evaluate the efficacy of a sleeve technique during endoscopic dacryocystorhinostomy (DCR) in primary nasolacrimal duct obstruction (NLDO) patients with a high lacrimal sac.
Kyoung-Nam Kim   +3 more
doaj   +1 more source

LPCAT3 as a Potential Drug Target for Ultraviolet Radiation–Induced Cataract: Insights From Multiomics Analysis

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Ultraviolet B (UVB) radiation is a major risk factor for cataract development, but the molecular mechanisms underlying this process, particularly the involvement of regulated cell death pathways such as ferroptosis, remain unclear. Transcriptomic, proteomic, and metabolomic analyses were performed on lens tissues from UVB‐induced cataract rat ...
Fei Xu   +4 more
wiley   +1 more source

Survey of intravitreal injection techniques among retina specialists in Israel [PDF]

open access: yes, 2016
Ori Segal,1,2 Yael Segal-Trivitz,1,3 Arie Y Nemet,1,2 Noa Geffen,1,2 Ronit Nesher,1,2 Michael Mimouni4 1Department of Ophthalmology, Meir Medical Center, Kfar Saba, 2The Sackler School of Medicine, Tel Aviv University, Tel Aviv, 3Department of ...
Geffen N   +5 more
core  

Perioperative visual loss with non-ocular surgery: Case report and review of literature

open access: yesIndian Journal of Ophthalmology, 2014
Perioperative visual loss (POVL), a rare but devastating complication, has been reported after spine, cardiac, and head-neck surgeries.The various causes include ischemic optic neuropathy, central or branch retinal artery occlusion, and cortical ...
Nidhi Pandey   +2 more
doaj   +1 more source

Clearance of Intravitreal Moxifloxacin

open access: yesInvestigative Opthalmology & Visual Science, 2006
To study the clearance of moxifloxacin after intravitreal injection in rabbits.Intravitreal injections of 200 microg/0.1 mL of moxifloxacin were administered to rabbits. Four eyes per time point after injection (1 hour and 6, 12, 24, and 36 hours) and three eyes at 48 hours, respectively, were enucleated and immediately frozen and stored at -80 degrees
Mohan N, Iyer   +5 more
openaire   +2 more sources

Staging concept for aging management: Definition, mechanism, and coping strategies

open access: yesVIEW, EarlyView.
We divided the overall aging stage into “pre‐aging”, “aging compensation”, and “aging disability”. For each stage, we delineate the clinical presentations, biological phenomena, theoretical underpinnings, and key management priorities. Abstract Aging, as a gradual and largely irreversible biological process, characterized by declining organismal ...
Zhonghan Wang   +6 more
wiley   +1 more source

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