Results 71 to 80 of about 64,045 (290)

LPCAT3 as a Potential Drug Target for Ultraviolet Radiation–Induced Cataract: Insights From Multiomics Analysis

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Ultraviolet B (UVB) radiation is a major risk factor for cataract development, but the molecular mechanisms underlying this process, particularly the involvement of regulated cell death pathways such as ferroptosis, remain unclear. Transcriptomic, proteomic, and metabolomic analyses were performed on lens tissues from UVB‐induced cataract rat ...
Fei Xu   +4 more
wiley   +1 more source

Perioperative visual loss with non-ocular surgery: Case report and review of literature

open access: yesIndian Journal of Ophthalmology, 2014
Perioperative visual loss (POVL), a rare but devastating complication, has been reported after spine, cardiac, and head-neck surgeries.The various causes include ischemic optic neuropathy, central or branch retinal artery occlusion, and cortical ...
Nidhi Pandey   +2 more
doaj   +1 more source

The impact of coronary artery bypass grafting on the short‐ and long‐term development and progression of diabetic retinopathy: A Danish national matched cohort study

open access: yesActa Ophthalmologica, EarlyView.
Abstract Purpose Diabetic retinopathy (DR) is a frequent long‐term complication of diabetes. While hemodynamic changes are known risk factors for DR, the effect of coronary artery bypass grafting (CABG) on the development of DR is poorly investigated.
Lukas Greve Maschoreck   +16 more
wiley   +1 more source

The efficacy of intravitreal interferon alpha-2b for the treatment of experimental endotoxin-induced uveitis

open access: yesIndian Journal of Ophthalmology, 2016
Purpose: To study the efficacy of intravitreal interferon alpha-2b for endotoxin-induced uveitis. Materials and Methods: A total of 36 rabbits were randomly allocated to one of the three groups: (1) received interferon plus balanced-salt solution; (2 ...
Mehrdad Afarid   +4 more
doaj   +1 more source

Clearance of Intravitreal Voriconazole

open access: yesInvestigative Opthalmology & Visual Science, 2007
Purpose To investigate the elimination rate of voriconazole after intravitreal injection in rabbits.Intravitreal injections of 35 microg/0.1 mL voriconazole were administered to rabbits. Vitreous and aqueous humor levels of voriconazole were determined at selected time intervals (1, 2, 4, 8, 16, 24, and 48 hours), and the in vitreous half-life was ...
Ying-Cheng, Shen   +6 more
openaire   +2 more sources

Exploring market dynamics of biological including biosimilar treatments for retinal diseases in Europe: An interrupted time‐series analysis

open access: yesActa Ophthalmologica, EarlyView.
Abstract Purpose To assess the impact of biosimilar ranibizumab and on‐patent faricimab market entry on pricing and utilization trends and describe national variation in off‐label bevacizumab use in Europe. Methods Interrupted time series analysis of quarterly sales data (Q1 2018–Q2 2024) in 11 European countries evaluated ranibizumab utilization and ...
Elif Car   +3 more
wiley   +1 more source

Management of macular epiretinal membrane by vitrectomy and intravitreal triamcinolone

open access: yesIndian Journal of Ophthalmology, 2014
A patient underwent successful vitrectomy for macular epiretinal membrane with anatomical and functional improvement. 10 weeks later, there was a recurrence of macular edema with corresponding visual decline.
Dhananjay Shukla
doaj   +1 more source

Adult‐onset Coats disease: A systematic review and meta‐analysis of imaging biomarkers and targeted therapies

open access: yesActa Ophthalmologica, EarlyView.
Abstract Coats disease diagnosed in adulthood is a rare idiopathic retinal telangiectatic vasculopathy that may differ in phenotype from childhood‐diagnosed cases. This systematic review synthesizes current evidence to characterize its clinical spectrum, imaging features, treatment outcomes and underlying mechanisms, with a focus on immunovascular ...
Catarina Francisco   +2 more
wiley   +1 more source

Widening use of dexamethasone implant for the treatment of macular edema

open access: yesDrug Design, Development and Therapy, 2017
Vincenza Bonfiglio, Michele Reibaldi, Matteo Fallico, Andrea Russo, Alessandra Pizzo, Stefano Fichera, Carlo Rapisarda, Iacopo Macchi, Teresio Avitabile, Antonio Longo Department of Ophthalmology, University of Catania, Catania, Italy Abstract: Sustained-
Bonfiglio V   +9 more
doaj  

Outcomes of Intravitreal Triamcinolone Acetonide Injection in Patients With Diabetic Macular Edema

open access: yesVan Tıp Dergisi, 2018
INTRODUCTION: To evaluate the effectiveness of intravitreal triamcinolone acetonide injection (IVTA) in chronic diabetic macular edema (DME) and to assess complications of treatment.
Lokman Balyen   +2 more
doaj   +1 more source

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