Results 261 to 270 of about 99,964 (316)

Intravitreal Injection Technique

Seminars in Ophthalmology, 2011
As the intravitreal injection of therapeutic medication plays an increasingly large role in ophthalmology, its implementation continues to be modified and refined. Variations in injection technique are discussed, and the authors combine their clinical and research experience with a review of the literature to propose a recommended intravitreal ...
Rishi R, Doshi, Sophie J, Bakri, Anne E, Fung   +2 more
openaire   +2 more sources

Experimental intravitreous cysticercosis

Graefe's Archive for Clinical and Experimental Ophthalmology, 1996
Cysticercosis is one of the parasitic diseases that most frequently affects the eye. The most common and severe manifestations of ocular infection are secondary to posterior segment involvement, which often leads to blindness and atrophy of the eye. The pathogenesis of ocular injury in this disease is poorly understood.
Arturo Santos, José A. Paczka, Juan M. Jiménez-Sierra, Patricia Chévez, Cecilio Velasco, Ana Flisser, Hugo Quiroz-Mercado, A. Santos   +7 more
openaire   +2 more sources

Intravitreal anti-VEGF drug delivery systems for age-related macular degeneration.

International journal of pharmaceutics, 2020
Age-related macular degeneration is the most common cause of vision loss in elderly people in developed countries. Nowadays, in clinical practice, three anti-VEGF drugs are commonly used (bevacizumab, aflibercept and ranibizumab), requiring repeated ...
A. Luaces-Rodríguez, C. Mondelo-García, I. Zarra-Ferro, M. González-Barcia, P. Aguiar, A. Fernández Ferreiro, F. Otero-Espinar   +6 more
semanticscholar   +1 more source

Trimethyl chitosan-hyaluronic acid nano-polyplexes for intravitreal VEGFR-2 siRNA delivery: Formulation and in-vivo efficacy evaluation.

Nanomedicine: Nanotechnology, Biology and Medicine, 2020
As vascular endothelial growth factor in choroidal neovascularization is a major cause of visual loss of the elderlies and diabetics, gene therapy may offer an alternative treatment.
Farkhondeh Chaharband, N. Daftarian, M. Kanavi, Reyhaneh Varshochian, Maliheh Hajiramezanali, Parisa Norouzi, E. Arefian, F. Atyabi, R. Dinarvand   +8 more
semanticscholar   +1 more source

Intravitreal Toxicity of Cotrimoxazole

Ophthalmic Surgery, Lasers and Imaging Retina, 1988
ABSTRACT We investigated the intravitreal toxicity of cotrimoxazole (trimethoprim 80 mg and sulfamethoxazole 400 mg/5 ml of injection fluid) in albino rabbits. Eyes injected intravitreally with 1600 µg/0.1 cc (reported in trimethoprim concentration) exhibited no histologic or abnormal electroretinographic responses after 14 days. A vitrectomy
R, Fiscella, G A, Peyman, A, Kimura, G, Small   +3 more
openaire   +2 more sources

INTRAVITREAL TOXICITY OF GARENOXACIN

Retina, 2006
To assess the retinal toxicity of varying concentrations of intravitreally injected garenoxacin.Twenty eyes of 20 New Zealand albino rabbits were used for this study. The animals were anesthetized with ketamine (35-50 mg/kg) and xylazine (3-5 mg/kg).
Mohammad Riazi, Esfahani, Abdul Ahad, Kazi, Gholam A, Peyman, John T, Dellacroce, Erdinc, Aydin   +4 more
openaire   +2 more sources

Incidence of endophthalmitis after intravitreal injection with and without topical antibiotic prophylaxis

European Journal of Ophthalmology, 2020
Purpose: The purpose was to compare the incidence of endophthalmitis after intravitreal injection with and without topical antibiotic prophylaxis. Methods: This is a single-center, retrospective case–control study.
Sónia Torres-Costa, Diogo Ramos, E. Brandão, Â. Carneiro, V. Rosas, A. Rocha-Sousa, F. Falcão-Reis, Manuel Falcão   +7 more
semanticscholar   +1 more source

Toxicity of Intravitreous Miconazole

Archives of Ophthalmology, 1982
Miconazole nitrate is a broad-spectrum antimycotic agent with low systemic and ocular toxicity. Since this drug does not adequately penetrate the vitreous cavity by topical, subconjunctival, or intravenous routes, we determined whether it can be given intravitreously for fungal endophthalmitis.
F I, Tolentino, C S, Foster, M, Lahav, L H, Liu, A R, Rabin   +4 more
openaire   +2 more sources

Intravitreal nanoparticles for retinal delivery.

Drug Discovery Today, 2019
Intravitreal injection is one of the major administration routes for the treatment of posterior ocular diseases. Intravitreal therapeutics usually suffer from unsatisfactory efficacy owing to fast clearance from the vitreous humour and insufficient ...
Xiaonan Huang, Y. Chau
semanticscholar   +1 more source

Toxicity of intravitreal oxiconazole

International Ophthalmology, 1989
Oxiconazole, a new imidazole derivative, has a broad antifungal spectrum in vitro and in vivo. Adult New Zealand white rabbits were injected intravitreally with doses ranging from 10 to 100 micrograms of this drug. Eyes were evaluated with preoperative and postoperative biomicroscopy and indirect ophthalmoscopy, electroretinography, and light ...
J A, Schulman, G A, Peyman, J, Dietlein, R, Fiscella   +3 more
openaire   +2 more sources