Results 271 to 280 of about 99,964 (316)

Systemic and Ocular Adverse Events with Intravitreal Anti-VEGF Therapy Used in the Treatment of Diabetic Retinopathy: a Review

Current Diabetes Reports, 2022
Jason A. Zehden, Xavier M Mortensen, A. Reddy, A. Zhang   +3 more
semanticscholar   +1 more source

Controlled release strategy designed for intravitreal protein delivery to the retina

Journal of Controlled Release, 2019
&NA; Therapeutic protein delivery directly to the eye is a promising strategy to treat retinal degeneration; yet, the high risks of local drug overdose and cataracts associated with bolus injection have limited progress, requiring the development of ...
V. Delplace, A. Ortín-Martínez, E. L. S. Tsai, Alan N. Amin, V. Wallace, M. Shoichet   +5 more
semanticscholar   +1 more source

INTRAVITREAL USE OF STREPTOMYCIN

Archives of Ophthalmology, 1949
EXPERIMENTAL streptomycin in treatment of intraocular infections have been published.1 Since, as has been shown by Leopold and Nichols, 1a streptomycin penetrates poorly from the blood stream into the normal vitreous humor, systemic administration of the drug is inadequate in therapy of infections of the vitreous. In a more recent series of experiments,
openaire   +2 more sources

Experimental Intravitreal Gentamicin

American Journal of Ophthalmology, 1976
Rabbits received intravitreal injections of gentamicin and indirect ophthalmoscopy, electroretinography, and histopathology determined relative toxicity. An intravitreal dose of 0.1 to 0.2 mg of commercially available gentamicin was well tolerated in the rabbit eye.
I G, Zachary, R K, Forster
openaire   +2 more sources

INTRAVITREAL TOXICITY OF MOXIFLOXACIN

Retina, 2006
To assess the retinal toxicity of various concentrations of intravitreally administered moxifloxacin, a fourth-generation fluoroquinolone.Ten New Zealand albino rabbits were divided into five groups. The initial concentration of moxifloxacin (400 mg/250 mL) was titrated using 5% dextrose solution to concentrations (320 microg/0.1 mL, 160 microg/0.1 mL,
Erdinc, Aydin, Abdul Ahad, Kazi, Gholam A, Peyman, Mohammad Riazi, Esfahani   +3 more
openaire   +2 more sources

Intravitreal Autotransplantation of Fibroblasts

American Journal of Ophthalmology, 1980
Tissue cultured skin fibroblasts autotransplanted into the vitreous cavity of rabbit eyes formed intravitreal strands that grew toward the medullary ray and optic nerve head and caused preretinal puckers and traction detachment. After four weeks, 32 of 51 eyes (63%) developed these changes.
G, Sugita, Y, Tano, R, Machemer, G, Abrams, A, Claflin, G, Fiorentino   +5 more
openaire   +2 more sources

Intravitreal Delivery of Ciprofloxacin

Journal of Ocular Pharmacology and Therapeutics, 1996
The objective of this work was to evaluate various methods of sustained delivery to achieve therapeutic intravitreal levels of ciprofloxacin as a potential therapy for endophthalmitis. Two types of intravitreal bioerodible sustained release devices of ciprofloxacin were evaluated in vitro.
D P, Hainsworth, J D, Conklin, J R, Bierly, D, Ax, P, Ashton   +4 more
openaire   +2 more sources

Endophthalmitis after Intravitreal Injection of Vascular Endothelial Growth Factor Inhibitors: Management and Visual Outcomes.

Ophthalmology (Rochester, Minn.), 2018
PURPOSE We describe the presentation of patients developing endophthalmitis after intravitreal injection with vascular endothelial growth factor (VEGF) inhibitors.
Kunyong Xu, E. Chin, S. Bennett, David F. Williams, E. Ryan, S. Dev, R. Mittra, P. Quiram, J. B. Davies, D. Parke, Jill B. Johnson, H. Cantrill, David Almeida   +12 more
semanticscholar   +1 more source

Communicating Intravitreal Cysticercosis

Ophthalmic Surgery, Lasers and Imaging Retina, 1989
ABSTRACT A viable intravitreal Cysticercus cellulosae communicating with subretinal space was identified in a 45year-old man. The cyst was removed in toto via the direct scleral approach without incident. To our knowledge this is the first report of intravitreal Cysticercus with subretinal extension removed successfully by the direct route ...
A, Kumar, L, Verma, P K, Khosla, H K, Tewari, S N, Jha   +4 more
openaire   +2 more sources

Toxicity of Intravitreal Interferon

Ophthalmic Surgery, Lasers and Imaging Retina, 1986
ABSTRACT We evaluated the toxicity of injecting human fibreblast Interferon intravitreally in rabbit eyes. A single intravitreal injection of 166,660 units/0.1 ml was nontoxic to ocular structures, as demonstrated by electroretinographic and histologie examination.
S, Vegh, G A, Peyman, J, Vernot, R, Fiscella   +3 more
openaire   +2 more sources