Results 71 to 80 of about 94,588 (272)

Aptamer‐Based Delivery Systems for VEGF and NGF Modulation in Ocular Therapies

Advanced Healthcare Materials, Volume 15, Issue 23, 19 June 2026.
Aptamer‐based delivery systems targeting NGF and VEGF hold significant potential for precise and sustained treatment of complex diseases affecting both the anterior and posterior segments of the eye. This review critically summarizes current strategies for NGF and VEGF delivery as well as VEGF sequestration, providing a clinical perspective on how ...
Nadine Best, Gizem Karabiyik, Gerd Geerling, Sarah Barbara Zwingelberg, Gregor Lang, Martin Humenik   +5 more
wiley   +1 more source

Intravitreal Injection of Anti-VEGF Antibody Induces Glomerular Endothelial Cells Injury

Case Reports in Nephrology, 2019
Introduction. Antiangiogenic agents that inhibit vascular endothelial growth factor have emerged as important tools in cancer therapy and ocular diseases. Their systemic use can induce renal limited microangiopathy.
F. Touzani, C. Geers, A. Pozdzik
doaj   +1 more source

The Comparative Risk of Endophthalmitis Following Intravitreal Injection with Bevacizumab, Aflibercept, and Ranibizumab

Retina, 2019
Purpose: To determine if sterile pre-loading of anti-VEGF agents reduces the risk of post-intravitreal injection endophthalmitis. Methods: This is a retrospective cohort study using medical claims data from a large, national U.S. insurer.
J. C. Bavinger, Yinxi Yu, B. Vanderbeek
semanticscholar   +1 more source

Necrotizing enterocolitis after intravitreal bevacizumab in an infant with Incontinentia Pigmenti – a case report

BMC Pediatrics, 2019
Background Incontinentia Pigmenti is a rare disease affecting multiple organs. Fifty of patients show affection of the eye with retinopathy and possible amaurosis being the worst outcome.
S. Kunzmann, T. Ngyuen, A. Stahl, J. M. Walz, M. M. Nentwich, C. P. Speer, K. Ruf   +6 more
doaj   +1 more source

Anti-Angiogenic Activity Of Bevacizumab-Bearing Dexamethasone-Loaded PLGA Nanoparticles For Potential Intravitreal Applications

International Journal of Nanomedicine, 2019
Purpose Age-related macular degeneration is a multifactorial disease involving inflammation and choroidal neovascularization. Vascular endothelial growth factor (VEGF) has been regarded as a potential therapeutic target to treat choroidal ...
Jiaxin Liu, Xueyan Zhang, Ge Li, Fei Xu, Shuang Li, Lesheng Teng, Youxin Li, Fengying Sun   +7 more
semanticscholar   +1 more source

Intravitreal Bevacizumab Injection Therapy in a Case with Choroidal Neovascular Membrane Secondary to Toxoplasmosis Retinochoroiditis

, 2014
A 57-year-old male patient presenting with visual loss in the left eye was diagnosed as choroidal neovascular membrane secondary to inactive toxoplasmosis retinochoroiditis scar. He underwent intravitreal bevacizumab injection as primary therapy.
Sirel Gür Güngör, Gürsel Yılmaz, Evin Şingar, İmren Akkoyun   +3 more
core   +1 more source

Angiographic results of retinal-retinal anastomosis and retinal-choroidal anastomosis after treatments in eyes with retinal angiomatous proliferation

Clinical Ophthalmology, 2012
Masaaki Saito,1 Tomohiro Iida,1,2 Mariko Kano,1 Kanako Itagaki11Department of Ophthalmology, Fukushima Medical University School of Medicine, Fukushima, 2Department of Ophthalmology, Tokyo Women's Medical University School of Medicine, Tokyo ...
Saito M, Iida T, Kano M, Itagaki K
doaj  

Intravitreal bevacizumab versus ranibizumab: Effects on the vessels of the fellow non-treated eye

Journal of Current Ophthalmology, 2019
Purpose: To evaluate the effects of anti-vascular endothelial growth factors (anti-VEGF) on the vessels of the non-treated eyes following intravitreal injections.
Mohammadreza Peyman, Alireza Peyman, Van C. Lansingh, Amirhossein Orandi, Visvaraja Subrayan   +4 more
doaj   +1 more source

Innovative Drug Delivery Systems for the Treatment of Glaucoma

MedComm – Biomaterials and Applications, Volume 5, Issue 2, June 2026.
This review aims to provide a comprehensive overview of current topical drug delivery strategies for ocular hypotensive agents in glaucoma therapy. Additionally, it discusses the potential impact of emerging nanotechnological and biomaterial‐based systems in shaping the future of ophthalmic drug delivery, with an emphasis on enhancing efficacy, safety,
Jing Chu, Junzhi Li, Zhenlin Chen, Jinyu Zhang, Siqi Feng, Jiaying Huang, Yawen Chu, Xue Zhou, Wei Wang, Shangsi Chen   +9 more
wiley   +1 more source

A randomised, double-masked phase III/IV study of the efficacy and safety of Avastin^® (Bevacizumab) intravitreal injections compared to standard therapy in subjects with choroidal neovascularisation secondary to age-related macular degeneration: clinical trial design

Trials, 2008
Background The management of neovascular age-related macular degeneration (nAMD) has been transformed by the introduction of agents delivered by intravitreal injection which block the action of vascular endothelial growth factor-A (anti-VEGF agents). One
Bunce Catey, Patel Praveen J, Tufail Adnan   +2 more
doaj   +1 more source