Results 71 to 80 of about 53,966 (218)

Insights into the modulation of age‐related macular degeneration: Molecular and systems‐level perspectives

Acta Ophthalmologica, Volume 104, Issue S293, Page S4-S35, October 2026.
ENGLISH SUMMARY In developed countries, age‐related macular degeneration (AMD) is the leading cause of visual impairment in the aging population. Understanding of its pathogenesis is limited and the number of patients is predicted to continue rising. AMD is classified into two main forms: dry and neovascular AMD (dAMD and nAMD, respectively).
Hanna Heloterä
wiley   +1 more source

Anticipated and Actual Pain Intensity in Patients Receiving Intravitreal Injections: A Cross Sectional Study

Nursing Open, Volume 13, Issue 9, September 2026.
ABSTRACT Aim To compare patients' anticipated pain intensity and actual pain experienced during intravitreal injection. Design The study used a quantitative, cross‐sectional design. Methods A single‐centre study was conducted in a group of 115 patients. Data were collected using medical records and the Numerical Rating Scale (NRS).
Ewa Kobos, Katarzyna Leszczyńska
wiley   +1 more source

Intravitreal Bevacizumab as Adjunctive Therapy for Bleb Survival in Trabeculectomy in Rabbit Eyes

Philippine Journal of Ophthalmology, 2012
Objective: To determine the effect of intravitreally administered bevacizumab, alone or as adjunct to mitomycin-C, after trabeculectomy on bleb survival and histology in rabbit eyes.
Margarita Echavez, MD, Manuel Agulto, MD, Ma. Imelda Veloso, MD   +2 more
doaj  

The impact of systemic long‐term medications for the development of age‐related macular degeneration

Acta Ophthalmologica, Volume 104, Issue 6, Page 674-681, September 2026.
Abstract Purpose Age‐related macular degeneration (AMD) is a leading cause of central vision loss in the elderly; however, the systemic factors that modulate its incidence and progression remain unclear. We sought to determine whether long‐term use of systemic medications, including diabetes and antithrombotic medications, corticosteroids and ...
Hanna Heloterä, Reijo Sund, Toni Rikkonen, Kai Kaarniranta   +3 more
wiley   +1 more source

Intravitreal Injection of Bevacizumab and Gas for Diabetic Premacular Hemorrhage with Active Fibrovascular Proliferation

, 2009
: Background To report the effect of intravitreal injection of bevacizumab and gas for the treatment of diabetic premacular hemorrhage with active fibrovascular proliferation.
施智偉;楊中美;陳慕師;王宗仁, SHIH, CHIH-WEI;YANG, CHUNG-MAY;CHEN, MUH-SHY;WANG, TSUNG-JEN   +1 more
core   +1 more source

Tremendous result of bevacizumab in malignant hypertensive retinopathy

Oman Journal of Ophthalmology, 2015
Signs of hypertensive retinopathy are common and are correlated with elevated blood pressure. Patients who have swelling of both optic discs and very high blood pressure (i.e., malignant retinopathy) need urgent antihypertensive treatment.
Ali M Al-Halafi
doaj   +1 more source

Microenvironment‐Responsive Drug Delivery Systems for Ocular Surface Diseases: Mechanisms, Applications, and Translational Challenges

Small Science, Volume 6, Issue 8, August 2026.
Microenvironment‐responsive drug delivery systems overcome ocular physiological barriers by responding to temperature, pH, ions, reactive oxygen species, and enzymes. This review bridges material design, performance evaluation, and clinical translation, offering actionable insights for treating dry eye disease, infectious keratitis, and corneal ...
Jiamin Liu, Liangbo Chen, Yao Fu, Siyi Zhang   +3 more
wiley   +1 more source

Multi‐site performance of the telemedicine retinopathy of prematurity severity score (tROP‐SS)

Acta Ophthalmologica, Volume 104, Issue 5, Page e590-e595, August 2026.
Abstract Objective This study aims to evaluate the performance of the telemedicine retinopathy of prematurity severity score (tROP‐SS) across all 14 NICUs in the TELEROP cohort against the modified ROP activity score (mROP‐ActS). Design Retrospective cohort study. Subjects The study included 2037 neonates who underwent ROP screening in 14 NICUs via the
Sarthak V. Shah, Arthur R. Brant, Cindy Zhao, Edward H. Wood, Shannon D. Scarboro, Jochen Kumm, Darius M. Moshfeghi   +6 more
wiley   +1 more source

Current Landscape and Future Perspectives of Diabetic Retinopathy Therapy: Pharmacological Targets, Precision Laser Technology, and Clinical Evidence

MedComm, Volume 7, Issue 7, July 2026.
Targeted biological agents targeting VEGF, integrin, dopamine D2 receptor, ROCK, and BCL‐XL have entered the clinical trial phase and deserve particular attention. The treatment paradigm has shifted toward personalized and precision medicine, positioning optimized SML as a promising adjunctive therapy.
Xinying Hu, Zhe Cha, Ao Lu, Wuping Xu, Xiaoqing Zhang, Sheng Miao, Haiwei Xu, Xuedong Xu   +7 more
wiley   +1 more source

Aptamer‐Based Delivery Systems for VEGF and NGF Modulation in Ocular Therapies

Advanced Healthcare Materials, Volume 15, Issue 23, 19 June 2026.
Aptamer‐based delivery systems targeting NGF and VEGF hold significant potential for precise and sustained treatment of complex diseases affecting both the anterior and posterior segments of the eye. This review critically summarizes current strategies for NGF and VEGF delivery as well as VEGF sequestration, providing a clinical perspective on how ...
Nadine Best, Gizem Karabiyik, Gerd Geerling, Sarah Barbara Zwingelberg, Gregor Lang, Martin Humenik   +5 more
wiley   +1 more source