Results 181 to 190 of about 8,508 (214)

Intravitreal Injection of Corticosteroid Attenuates Leukostasis and Vascular Leakage in Experimental Diabetic Retina [PDF]

open access: yesInvestigative Opthalmology & Visual Science, 2005
Recently, intravitreal injection of corticosteroids has been in wide use as a treatment for diabetic macular edema, and the outcomes have been favorable. However, the exact mechanism remains unclear. The hypothesis for the current study was that intravitreal corticosteroids may improve diabetic retinal edema by amelioration of blood-retinal barrier ...
Hiroshi Tamura   +2 more
exaly   +3 more sources

Inhibition of Intraocular Proliferations with Intravitreal Corticosteriods

American Journal of Ophthalmology, 1980
Autotransplantation of one fourth million tissue cultured fibroblasts from rabbit rump skin into the vitreous cavity resulted in intravitreal strand formation and traction retinal detachment (27 of 47 eyes, 57%). A single intravitreal injection of 1 mg of dexamethasone alcohol inhibited fibroblast growth as judged by the significantly reduced number of
Y, Tano   +3 more
openaire   +2 more sources

Efficacy and safety of intravitreal and periocular injection of corticosteroids in noninfectious uveitis: a systematic review

Survey of Ophthalmology, 2022
Uveitis is among the leading causes of visual loss in the working age population. In noninfectious uveitis, corticosteroids are the first line therapy. We sought to review systematically the evidence regarding the regional corticosteroid delivery modalities in the treatment of noninfectious uveitis.
Rafael José-Vieira   +4 more
openaire   +2 more sources

INTRAVITREAL CORTICOSTEROIDS AS AN ADJUNCT IN THE TREATMENT OF BACTERIAL AND FUNGAL ENDOPHTHALMITIS

Retina, 1992
The use of intravitreal corticosteroids in the management of endophthalmitis remains controversial. Several clinical and experimental reports are reviewed that suggest that intravitreal corticosteroid therapy, when used in conjunction with antibiotics with and without vitrectomy, reduces the intraocular inflammatory process and secondary complications ...
J A, Schulman, G A, Peyman
openaire   +2 more sources

Corticosteroid intravitreal implants vs. ranibizumab for the treatment of vitreoretinal disease

Current Opinion in Ophthalmology, 2013
Three long-acting corticosteroid implants are now available for the treatment of retinal disease, offering control of macular edema and inflammation for between 6 months and up to 3 years. This review evaluates their efficacy and side-effect profile in comparison with the antivascular endothelial growth factor agent ranibizumab in diabetic macular ...
Oliver, Comyn   +2 more
openaire   +2 more sources

PP077 Intravitreal Corticosteroids In Macular Edema: Quality Of The Evidence

International Journal of Technology Assessment in Health Care, 2017
INTRODUCTION:Treatment options for macular edema include intravitreal corticosteroids (1). Traditionally, an injectable suspension of triamcinolone acetonide (TA) had been employed off-label (2); in recent years, authorities have approved sustained-release drug delivery systems (DDSs) for corticosteroids (3).
Marco Marchetti   +4 more
openaire   +1 more source

Corticosteroid Intravitreal Implants

2012
Intraocular implants developed for ocular inflammation which release glucocorticoids for a prolonged period within the vitreous cavity make use of either a bioerodible polymer (dexamethasone in polylactic acid-coglycolic acid matrix) or non-erodible implantable device (fluocinolone acetonide, FA, in a polyvinyl acetate/silicone laminate ...
openaire   +2 more sources

Comparative toxicity of 4 commonly used intravitreal corticosteroids on rat retina

Canadian Journal of Ophthalmology, 2009
To investigate the effects of 4 commonly used steroids (dexamethasone, triamcinolone, betamethasone, and methylprednisolone) on 50 retinas of 25 adult pigmented rats.Experimental animal study.Twenty-five pigmented Long-Evans male rats.Each steroid drug with 2 different doses (0.025 mL and 0.050 mL) was injected into the vitreous of each eye of 5 rats ...
Mehmet, Citirik   +3 more
openaire   +2 more sources

EFFECTS OF INTRAVITREAL CORTICOSTEROID IN THE TREATMENT OF STAPHYLOCOCCUS AUREUS–INDUCED EXPERIMENTAL ENDOPHTHALMITIS

Retina, 2008
To investigate whether intravitreal injection of dexamethasone in addition to antibiotics can minimize intraocular tissue injury caused by Staphylococcus aureus endophthalmitis.Albino rabbits were infected with an intravitreal injection of 1000 colony-forming units of S. aureus. The rabbits were randomized to receive no treatment (control group; n = 2),
Herminia Miño, De Kaspar   +5 more
openaire   +2 more sources

Cytomegalovirus retinitis after low-dose intravitreous triamcinolone acetonide in an immunocompetent patient: a warning for the widespread use of intravitreous corticosteroids

International Ophthalmology, 2010
We report the case of an immunocompetent 78-year-old woman who developed cytomegalovirus (CMV) retinitis after a single intravitreous injection of triamcinolone acetonide (IVTA). Review of medical records. The patient with macular edema secondary to branch retinal vein occlusion developed peripheral retinitis with hemorrhagic and inflammatory vascular ...
Dora, Vertes   +2 more
openaire   +2 more sources

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