Results 181 to 190 of about 1,540,879 (346)

Turnover of Microaneurysms After Intravitreal Injections of Faricimab for Diabetic Macular Edema

, 2023
Yoshihiro Takamura, Yutaka Yamada, Masakazu Morioka, Makoto Gozawa, Takehiro Matsumura, Masaru Inatani   +5 more
openalex   +1 more source

Thrombotic Microangiopathy and Acute Kidney Injury Induced After Intravitreal Injection of Vascular Endothelial Growth Factor Inhibitors VEGF Blockade-Related TMA After Intravitreal Use [PDF]

, 2020
Ramy M. Hanna, Ngoc-Tram Tran, Sapna S. Patel, Jean Hou, Kenar D. Jhaveri, Rushang Parikh, Umut Selamet, Lena Ghobry, Olivia Wassef, Marina Barsoum, Vanesa Bijol, Kamyar Kalantar‐Zadeh, Alex Y. Pai, Alpesh Amin, Baruch Kupperman, Ira Kurtz   +15 more
openalex   +1 more source

Outcome of intravitreal Avastin® injections in patients with macular oedema in Uganda: a cohort study [PDF]

, 2022
Rachel R. Kabunga, John Onyango, Sam Ruvuma, Simon Arunga   +3 more
openalex   +1 more source

Optimization of the Nonclinical Biological Evaluation of Medical Devices Using Toxicologic Pathology Best Practices

Advanced Healthcare Materials, Volume 15, Issue 3, 19 January 2026.
Nonclinical evaluation of biological responses to implanted medical devices and combination products in animals is required to predict possible outcomes and risks in patients. This paper describes globally accepted pathology “best practices” that 1) effectively address ISO standards and current regulatory guidance for medical device development and 2 ...
Kathleen A. Funk, JoAnn C. L. Schuh, Brad Bolon, Valerie S. Thomas, Jeffrey I. Everitt, Abraham Nyska, Jaime Paulin   +6 more
wiley   +1 more source

Methotrexate‐Loaded Liposomal Formulation Enables 6‐Week Sustained Intraocular Therapeutic Drug Release in a Porcine Model

Advanced Healthcare Materials, Volume 15, Issue 1, 9 January 2026.
A liposomal formulation for methotrexate enables minimally invasive, sustained intraocular drug delivery for over six weeks with a single injection. Developed for treating intraocular diseases like lymphoma and PVR, it offers excellent biocompatibility in vivo in a porcine model.
Maximilian Hammer, Lea Skrzypczyk, Sabrina Wohlfart, Bryan Calder Ackermann, Ludwig Geisweid, Simon William Pohl, Margarita Karaivanova, Jonathan Herth, Victor Aristide Augustin, Alexander Studier‐Fischer, Tina Sackmann, Leon Kaulen, Anna Steyer, Walter Mier, David H Steel, Kanmin Xue, Gerd Uwe Auffarth, Philipp Uhl   +17 more
wiley   +1 more source

Intravitreal injection history and cataract surgery complications: A multicenter retrospective cohort

AJO International
Purpose: To evaluate whether a recent history of intravitreal injection is associated with postoperative complications after cataract surgery in a large, real-world cohort. Design: Retrospective, propensity score–matched cohort study.
Justus Zemberi, Julian Peregoff, Matthew Santos   +2 more
doaj   +1 more source

Single‐Cell RNA Sequencing of Retina Reveals Nna1 Upregulation in Myopic Diabetic Retinopathy as a Protective Factor Against Diabetic Damage

Advanced Science, Volume 13, Issue 5, 27 January 2026.
This study investigates a schematic overview of the mechanistic pathways. The relationship between myopia and DR has long been of clinical interest. In diabetic mice, Nna1 expression is downregulated, whereas in diabetic mice with FDM, Nna1 expression is upregulated–particularly in Müller cells–accompanied by decreased vascular endothelial growth ...
Lihui Xie, Yingjun Cai, Bolin Chen, Bowen Li, Jing Zou, Huizhuo Xu   +5 more
wiley   +1 more source

Intravitreal injection of mitochondrial DNA induces cell damage and retinal dysfunction in rats [PDF]

, 2022
Yue Guo, Dekang Gan, Fangyuan Hu, Yun Cheng, Jian Yu, Boya Lei, Qinmeng Shu, Ruiping Gu, Gezhi Xu   +8 more
openalex   +1 more source

Continuous Suppression of Pathological Retinal and Choroidal Neovascularization in Cynomolgus Monkeys via Noninvasive Ophthalmic Delivery of a Novel Anti‐VEGFA Nanobody and Proprietary Penetratin Analog Formulation

Advanced Science, Volume 13, Issue 1, 5 January 2026.
Pathological retinal/choroidal neovascularization drives vision loss in DR and AMD. Current anti‐VEGF injections, while effective, require invasive, frequent administration. Pene/LQ015, is developed a novel topical anti‐VEGFA nanobody formulation achieving therapeutic intraocular levels through penetratin analog‐enhanced delivery.
Chong Chen, Min Zhu, Xingyan Fan, Kangjia Lv, Kuan Jiang, Yuchen Zhang, Haoliang Zhang, Xinming Qi, Benjamin TK Lee, Yakun Wan, Gang Wei, Kun Liu, Xun Xu   +12 more
wiley   +1 more source

Intravitreal vs. Subtenon Triamcinolone Acetonide Injection as Adjunctive for Retinal Photocoagulation in Diabetic Macular Edema [PDF]

Namir Mahmoud, Mohammed Abouelwafa, Mahmoud Namir, Mohammed   +3 more
openalex   +1 more source