Results 131 to 140 of about 31,184 (259)
Patients' tolerance of bimanual lid retraction versus a metal speculum for intravitreal injections
Clinical Ophthalmology, 2016 Khadijah Alattas Department of Ophthalmology, College of Medicine, King Abdulaziz University, Jeddah, Saudi Arabia Objective: To compare patients’ acceptance of and correlate their pain level for bimanual versus metal speculum fixation in ...
Alattas K
doaj
Humanin Mitigates Aβ‐Induced Retinal Pigment Epithelium Injury via AMPK‐Beclin1‐Dependent Mitophagy
Aging Cell, Volume 25, Issue 7, July 2026.Humanin (HN) enhanced the clearance of Aβ‐accumulated mitochondria in the RPE while preserving retinal function and RPE barrier integrity. HN activated AMP‐activated protein kinase (AMPK), leading to phosphorylation of ULK1 and Beclin1, which promoted the interaction between Beclin1 and Parkin and their translocation to mitochondria.
Ha Young Jang +7 more
wiley +1 more source
A narrative review of the psychological impact of intravitreal injections
Intravitreal injections (IVI) are a common, effective therapy for multiple retinal diseases although can be associated with significant psychological effects that reduce adherence to treatment. We reviewed the psychological impacts of IVI to characterise
Chan, WO +5 more
core +1 more source
Diabetes, Obesity and Metabolism, Volume 28, Issue 7, Page 5614-5626, July 2026.ABSTRACT Aims Diabetic retinopathy (DR) is linked to elevated risks of cerebrovascular diseases. Whether sodium‐glucose cotransporter‐2 inhibitors (SGLT2i) reduce stroke risk in patients with type 2 diabetes (T2D) and DR remains uncertain. Materials and Methods We conducted a retrospective cohort study using the TriNetX Research Network.
Kuo‐En Chen +3 more
wiley +1 more source
Feasibility of intravitreal erythropoietin injections in humans
, 2009 International audiencePreclinical data suggest that intravitreally administered erythropoietin (EPO) is both neuroprotective and safe.
Feltgen, Nicolas +4 more
core +1 more source
Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells
FEBS Open Bio, Volume 16, Issue 6, Page 1150-1165, June 2026.Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi +7 more
wiley +1 more source
Safety Evaluation of Bilateral Same-Day Intravitreal Injection of Faricimab
Ophthalmology and TherapyIntroduction Intravitreal injection of anti-vascular endothelial growth factor (VEGF) agents is the most commonly performed ophthalmic procedure. Many retinal specialists routinely perform same-day bilateral intravitreal anti-VEGF injections, in order to
Michael D. Karampelas +2 more
doaj +1 more source
Case Reports in OphthalmologyIntroduction: We report on one case of age-related macular degeneration and one case of diabetic macular edema with concomitant retinal arterial macroaneurysm (RAM) that were treated with anti-vascular endothelial growth factor (VEGF) intravitreal ...
Michiko Takamiya
doaj +1 more source
Aptamer‐Based Delivery Systems for VEGF and NGF Modulation in Ocular Therapies
Advanced Healthcare Materials, Volume 15, Issue 23, 19 June 2026.Aptamer‐based delivery systems targeting NGF and VEGF hold significant potential for precise and sustained treatment of complex diseases affecting both the anterior and posterior segments of the eye. This review critically summarizes current strategies for NGF and VEGF delivery as well as VEGF sequestration, providing a clinical perspective on how ...
Nadine Best +5 more
wiley +1 more source
, 2016 Kui Huang,1 Marla B Sultan,2 Duo Zhou,3 Charles S Tressler,4 Jingping Mo1 1Epidemiology, Worldwide Safety and Regulatory, 2Clinical Sciences, Global Innovative Products Business, 3Clinical Statistics, Global Established Pharma Business, 4Safety ...
Sultan MB +4 more
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