Results 131 to 140 of about 162,637 (248)
Kui Huang,1 Marla B Sultan,2 Duo Zhou,3 Charles S Tressler,4 Jingping Mo1 1Epidemiology, Worldwide Safety and Regulatory, 2Clinical Sciences, Global Innovative Products Business, 3Clinical Statistics, Global Established Pharma Business, 4Safety ...
Sultan MB +4 more
core
Abstract The global demand for intravitreal anti‐vascular endothelial growth factor (anti‐VEGF) therapy continues to rise, straining ophthalmic capacity worldwide. Task shifting from physicians to trained non‐physician healthcare professionals has emerged as a potential strategy to expand service delivery.
Trang Truong Laursen +4 more
wiley +1 more source
The oscillatory response of the electroretinogram and neuronal adaptation
Abstract After more than 50 years, there still remains a challenge and an interest to know more as well as extend and deepen our understanding of the small rapid wavelets, the oscillatory potentials (OPs), of the electroretinogram (ERG) and the neuronal adaptation of the retina.
Lillemor Wachtmeister, Anders Eklund
wiley +1 more source
Feasibility of intravitreal erythropoietin injections in humans
International audiencePreclinical data suggest that intravitreally administered erythropoietin (EPO) is both neuroprotective and safe.
Feltgen, Nicolas +4 more
core +1 more source
Abstract Purpose To assess in Royal College of Surgeons (RCS) rats if the combination of two previously documented neuroprotective strategies: minocycline administration and bone marrow–derived mononuclear cells (BM‐MNCs) intravitreal transplantation, offers enhanced neuroprotection compared with each treatment alone.
Alba Videla‐Ristol +6 more
wiley +1 more source
The impact of systemic long‐term medications for the development of age‐related macular degeneration
Abstract Purpose Age‐related macular degeneration (AMD) is a leading cause of central vision loss in the elderly; however, the systemic factors that modulate its incidence and progression remain unclear. We sought to determine whether long‐term use of systemic medications, including diabetes and antithrombotic medications, corticosteroids and ...
Hanna Heloterä +3 more
wiley +1 more source
Adjunctive use of intravitreal dexamethasone in presumed bacterial endophthalmitis [PDF]
Includes abstract. Includes bibliographical references (leaves 33-36)
Albrecht, Eric
core
Abstract Purpose To describe the associations of treated neovascular AMD with the risk of disability, falls, fractures and mood disorders in a large sample representative of the French population. Methods Analyses were based on 77 582 individuals belonging to the ‘Echantillon Généraliste des Bénéficiaires’, a 1/97 random sample of the French population,
Cécile Delcourt +6 more
wiley +1 more source
A narrative review of the psychological impact of intravitreal injections
Intravitreal injections (IVI) are a common, effective therapy for multiple retinal diseases although can be associated with significant psychological effects that reduce adherence to treatment. We reviewed the psychological impacts of IVI to characterise
Chan, WO +5 more
core +1 more source
Schematic workflow of the translational study. ABSTRACT Wet age‐related macular degeneration (wAMD) is a leading cause of vision loss, and human dose selection for ocular therapeutics remains a key translational challenge. We developed a physiologically based pharmacokinetic (PBPK) model for EB‐203 to guide dose selection by translating preclinical ...
Woojin Jung +7 more
wiley +1 more source

