Results 131 to 140 of about 39,591 (271)

Retinal ganglion cell function after repeated intravitreal injections of ranibizumab in patients with age-related macular degeneration

open access: yesClinical Ophthalmology, 2012
Tomoharu Nishimura, Shigeki Machida, Tomomi Harada, Daijiro KurosakaDepartment of Ophthalmology, Iwate Medical University School of Medicine, Morioka, Iwate, JapanBackground: The purpose of this study was to evaluate the safety of intravitreal ...
Nishimura T   +3 more
doaj  

Effect of intravitreal injections due to neovascular age-related macular degeneration on retinal nerve fiber layer thickness and minimum rim width: a cross sectional study

open access: yesBMC Ophthalmology
Purpose The present study tested the hypothesis that repeated anti-VEGF injections are associated with reduced retinal nerve fiber layer (RNFL) and minimum rim width (MRW) of the optic nerve head. Patients and methods Sixty-six patients with a history of
Agnes Boltz   +4 more
doaj   +1 more source

Plantar fascia thickness in type 1 diabetes mellitus patients: Clinical associations and metabolic correlates

open access: yesJournal of Diabetes Investigation, EarlyView.
Ultrasound‐measured plantar fascia thickness is associated with microvascular complications and glycemic control in individuals with type 1 diabetes, suggesting PFT as a potential non‐invasive tool for clinical assessment. In addition, improved thickness values were observed in patients using automated insulin delivery systems.
Giulia Casadei   +9 more
wiley   +1 more source

Sodium–glucose cotransporter 2 inhibition and injection burden in mild diabetic macular edema: An exploratory post hoc analysis of the COMET trial

open access: yesJournal of Diabetes Investigation, EarlyView.
Combining oral sodium‐glucose cotransporter 2 inhibitors with reduced intravitreal injections of anti‐vascular endothelial growth factor showed potential efficacy for mild diabetic macular edema. ABSTRACT Aims To investigate the potential of sodium–glucose cotransporter 2 inhibitors (SGLT2i) as a less invasive treatment option for mild diabetic macular
Yoko Takatsuna   +6 more
wiley   +1 more source

Evaluation for endotoxin in intraocular materials used during phacoemulsification surgery using a recombinant factor C assay

open access: yesVeterinary Ophthalmology, Volume 28, Issue 2, Page 481-485, March 2025.
Abstract Objective Cataract surgery remains the sole method to resolve blindness secondary to cataract formation. One complication includes fibrin web formation post‐operatively. This study aimed to investigate the presence of endotoxin within materials used during cataract surgery as a possible cause of fibrin web phenomenon. Methods Preservative‐free
Taylor A. Opgenorth   +3 more
wiley   +1 more source

Safety Evaluation of Bilateral Same-Day Intravitreal Injection of Faricimab

open access: yesOphthalmology and Therapy
Introduction Intravitreal injection of anti-vascular endothelial growth factor (VEGF) agents is the most commonly performed ophthalmic procedure. Many retinal specialists routinely perform same-day bilateral intravitreal anti-VEGF injections, in order to
Michael D. Karampelas   +2 more
doaj   +1 more source

The Management of Two Cases with Retinal Arterial Macroaneurysm by Anti-Vascular Endothelial Growth Factor

open access: yesCase Reports in Ophthalmology
Introduction: We report on one case of age-related macular degeneration and one case of diabetic macular edema with concomitant retinal arterial macroaneurysm (RAM) that were treated with anti-vascular endothelial growth factor (VEGF) intravitreal ...
Michiko Takamiya
doaj   +1 more source

Techniques for subretinal injections in animals

open access: yesVeterinary Ophthalmology, Volume 28, Issue 2, Page 506-518, March 2025.
Abstract Subretinal injections are not commonly performed during clinical treatment of animals but are frequently used in laboratory animal models to assess therapeutic efficacy and safety of gene and cell therapy products. Veterinary ophthalmologists are often employed to perform the injections in the laboratory animal setting, due to knowledge of ...
Ryan F. Boyd, Simon M. Petersen‐Jones
wiley   +1 more source

Role of additional topotecan injections (plus two) in reducing recurrence rate in retinoblastoma of group D and group E patients: a retrospective study

open access: yesBMJ Open Ophthalmology
Objective To evaluate the effectiveness of administering additional intravitreal topotecan injections (plus two) in reducing the recurrence rate in patients with advanced retinoblastoma (RB).Methods and analysis This retrospective, non-comparative and ...
Qiang Liu   +6 more
doaj   +1 more source

Visual Responses in Mice Lacking Critical Components of All Known Retinal Phototransduction Cascades [PDF]

open access: yes, 2010
The mammalian visual system relies upon light detection by outer-retinal rod/cone photoreceptors and melanopsin-expressing retinal ganglion cells. Gnat1(-/-); Cnga3(-/-); Opn4(-/-) mice lack critical elements of each of these photoreceptive mechanisms ...
Allen, AE   +4 more
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